FWIW It seems to published in a journal with a company that also publishes studies showing how music can help Alzheimer's etc. Not a particularly reputable source.
Is music helping Alzheimer's patients considered implausible?
Vitamin D Supplementation Improves Cognitive Function: 12-month RCT
21–30 of 198 posts
Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT
#22It's worth noting that vitamin D has a lot of high-confidence but low-effect results going for it, including a lot of strong meta-analysis over many health outcomes. What I mean by this is that it usually seems to conclusively either do something beneficial, but minor, almost nothing in the case of many studies, and in the case of some others, something very beneficial (as we've seen a few of in relation to covid rec…
> and almost no risks
This isn't true--especially for Vitamin D. We have several doctors at this point who deal with cases where too much Vitamin D causes Calcium uptake issues and affects cognition and heart function.
Vitamin D is NOT something like Vitamin C. Your body easily dumps excessive Vitamin C so you can take fairly massive doses with no real ill effects.
Your body has a much tougher time excreting Vitamin D--so large doses of Vitamin D can cause issues and accumulate.
Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT
#23It's worth noting that vitamin D has a lot of high-confidence but low-effect results going for it, including a lot of strong meta-analysis over many health outcomes. What I mean by this is that it usually seems to conclusively either do something beneficial, but minor, almost nothing in the case of many studies, and in the case of some others, something very beneficial (as we've seen a few of in relation to covid rec…
It is fat soluble. You can develop toxicity, and the effects are not trivial: https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-h...
It seems based on casual reading of research that more people are deficient than not and dosing to toxic levels is unlikely. But it's not a bad idea to do this under the care of a doctor.
Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT
#24It's worth noting that vitamin D has a lot of high-confidence but low-effect results going for it, including a lot of strong meta-analysis over many health outcomes. What I mean by this is that it usually seems to conclusively either do something beneficial, but minor, almost nothing in the case of many studies, and in the case of some others, something very beneficial (as we've seen a few of in relation to covid rec…
almost no risks or real costs I worry a little about risk compensation, or whatever the equivalent is for diet. That is to say, if I feel like I'm all set on vitamins & minerals via pills, maybe I don't need to try so hard to eat my fruits & vegetables anymore...
Worth noting that the above mostly talks above Vitamin D specifically, not multivitamins. D is the only one you do not naturally get from food (ignoring fortified food), and it also as mentioned above one of the cheaper ones. Multivitamins are far more expensive in general.
Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT
#25Funny -- I was just digesting a competing study released recently[0] which showed little-to-no benefit from vitamin D, Omega 3 fatty acids, and exercise (either alone or in combinations). That study used 5X the daily vitamin D as this one. So I guess the jury's still out and I may choose to continue to err on the side of supplementing vitamin D. [0] https://www.upi.com/Health_News/2020/11/10/Study-Little-bene...
One important factor in vitamin studies is the prevalence of vitamin deficiency in a particular population. E.g. vitamin D in the US might not be as effective because it is already added into many food products, e.g. milk, which is not the case for other countries.
Even within a population, vitamin D deficiency will vary by lifestyle, skin tone, and climate. All three of which vary a lot in the US.
Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT
#26Milk and sunshine probably cheaper
Vit. D supplementation is dirt cheap. Like $15 for a years worth. That’s a lot cheaper than milk.
Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT
#27Milk and sunshine probably cheaper
Milk contains 100 IU vitamin D per cup in the US. A typical supplement dose is 2000 IU.
Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT
#28Earlier quoted context omitted.
Or just get some sunshine! It's likely there are other benefits, besides just the vitamin D.
Sure, but the winter climates in many geographical regions don’t provide adequate sunlight during winter.
I was pretty amazed to Discover that Spirit Airlines is doing round trip flights for $75 to Orlando from my local airport. If you’re in the Midwest in a midsized city that’s cold and dreary in winter there’s a good chance you can find a similar deal.
Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT
#29Funny -- I was just digesting a competing study released recently[0] which showed little-to-no benefit from vitamin D, Omega 3 fatty acids, and exercise (either alone or in combinations). That study used 5X the daily vitamin D as this one. So I guess the jury's still out and I may choose to continue to err on the side of supplementing vitamin D. [0] https://www.upi.com/Health_News/2020/11/10/Study-Little-bene...
> 40.7% of participants had 25(OH)D levels of less than 20 ng/mL at baseline, and according to current guidelines, all were allowed to take 800 IU/d of supplemental vitamin D outside the study medication.
So, even the controls were given D3 supplements if they were deficient. That kind of throws the whole study into question.
Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT
#30Earlier quoted context omitted.
Sure, but the winter climates in many geographical regions don’t provide adequate sunlight during winter.
I was pretty amazed to Discover that Spirit Airlines is doing round trip flights for $75 to Orlando from my local airport. If you’re in the Midwest in a midsized city that’s cold and dreary in winter there’s a good chance you can find a similar deal.
A lot of this interest in vitamin D is motivated by the desire to not die from getting infected with sars-cov-2. Or not dying in general. Travel like that is counter-productive currently.