Live data from Hacker News

Severe brain injury and paralysis temporarily reversed with a sleeping pill

sciencedirect.com

21–30 of 187 posts

Re: Severe brain injury and paralysis temporarily reversed with a sleeping pill

#21
post #9

Things like these makes me realize how little we know about the functioning of brain. Manipulating brain digitally would be perhaps one of the biggest technological revolution after industrial revolution.

Sometimes I wish I was smart enough to have gotten involved with things like neuroscience. I watched part of a lecture on certain brain functions a good while back, regarding the mechanics of various mental illnesses, and it was incredibly fascinating. Such a powerful organ that we simply can't understand well enough.

Re: Severe brain injury and paralysis temporarily reversed with a sleeping pill

#22
post #17

Earlier quoted context omitted.

You could phrase this much more kindly.

I believe it would be on you to interpret it more charitably. I'm unsure how you've found a way to take offense with words that aren't readily associated with malice.

Your bizarre use of "malice" explains a lot about why you don't see how "slither" and "come back to life" are plainly uncharitable phraseology to associate with people dealing with tbi. If you can't figure that out, buddy, I don't know what to tell ya.

Re: Severe brain injury and paralysis temporarily reversed with a sleeping pill

#23
post #11

Zolpidem, I use this pill to sleep and works fantastic for me. My MD told me that regular use could lead to dementia and the risk for addiction is considerable. I've tried antidepressants to sleep but always wake up with a headache, the feeling of it it's not great either. But with this one, never had an issue.

Dementia as a side effect? Aren’t you scared of that?

Check this out:

Zolpidem may cause serious or possibly life-threatening sleep behaviors. Some people who took zolpidem got out of bed and drove their cars, prepared and ate food, had sex, made phone calls, sleep-walked, or were involved in other activities while not fully awake. After they woke up, these people were unable to remember what they had done. Tell your doctor if you have ever had an unusual sleep behavior while taking zolpidem. Be sure that your family or caregiver are aware that these symptoms are serious and to call your doctor if they occur. Stop taking zolpidem and call your doctor right away if you find out that you have been driving or doing anything else unusual while you were sleeping.

https://medlineplus.gov/druginfo/meds/a693025.html

Re: Severe brain injury and paralysis temporarily reversed with a sleeping pill

#24
post #9

Things like these makes me realize how little we know about the functioning of brain. Manipulating brain digitally would be perhaps one of the biggest technological revolution after industrial revolution.

Sometimes I wish I was smart enough to have gotten involved with things like neuroscience. I watched part of a lecture on certain brain functions a good while back, regarding the mechanics of various mental illnesses, and it was incredibly fascinating. Such a powerful organ that we simply can't understand well enough.

You probably are smart enough. It’s never to late to learn and contribute.

Re: Severe brain injury and paralysis temporarily reversed with a sleeping pill

#25
post #17

Earlier quoted context omitted.

I believe it would be on you to interpret it more charitably. I'm unsure how you've found a way to take offense with words that aren't readily associated with malice.

Your bizarre use of "malice" explains a lot about why you don't see how "slither" and "come back to life" are plainly uncharitable phraseology to associate with people dealing with tbi. If you can't figure that out, buddy, I don't know what to tell ya.

I think you are off base here. OP’s comment isn’t malicious.

Re: Severe brain injury and paralysis temporarily reversed with a sleeping pill

#26
post #11

Zolpidem, I use this pill to sleep and works fantastic for me. My MD told me that regular use could lead to dementia and the risk for addiction is considerable. I've tried antidepressants to sleep but always wake up with a headache, the feeling of it it's not great either. But with this one, never had an issue.

Dementia as a side effect? Aren’t you scared of that?

It’s a crap calculation but dementia years away is better than a life without proper sleep. You might not make it to those dementia years or skip it through some other process-like not triggering it. I’ve accepted similar trade offs with medication for chronic migraine (as in literally every day sometimes multiples per day). Functioning today definitely matters more than decades down the road if that’s what it truly takes.

Re: Severe brain injury and paralysis temporarily reversed with a sleeping pill

#27
post #13

Reading the HN title, I was immediately reminded of the Oliver Sacks book Awakenings[1]. He discovered that the drug L-DOPA could temporarily awaken encephalitis patients from a coma-like state. I wonder if the article's title "Awakening after a sleeping pill" is a reference to that book. 1. https://en.wikipedia.org/wiki/Awakenings_(book)

There's a House M.D. episode about this. It's one of my favourite episodes, but if you weren't already following the show it wouldn't be the best one to start on, as it involved Wilson doing a lot of analysis on House's way of thinking which you'd lack context on.

https://en.m.wikipedia.org/wiki/Son_of_Coma_Guy

Re: Severe brain injury and paralysis temporarily reversed with a sleeping pill

#28

Zolpidem is famous for this, although it’s raised more questions than answers. This particular phenomenon has been known since the early 2000s; NYT has a good write up about it: https://www.nytimes.com/2011/12/04/magazine/can-ambien-wake-...

After taking it for sleep, I think it should be researched for way more. It’s clearly rewiring things.

Re: Severe brain injury and paralysis temporarily reversed with a sleeping pill

#30
post #11

Zolpidem, I use this pill to sleep and works fantastic for me. My MD told me that regular use could lead to dementia and the risk for addiction is considerable. I've tried antidepressants to sleep but always wake up with a headache, the feeling of it it's not great either. But with this one, never had an issue.

Dementia as a side effect? Aren’t you scared of that?

I take medication that results in Parkinsonism Syndrome to some extent. It sucks, and it's very frustrating when it manifests.

That said, without the medication I'd be miserable and might not even be alive.

One of these is better than the other, so it's the choice I make.

Post reply on HN