About the name: Feluda is a famous detective character [1] created by the director Satyajit Ray [2]:
India's new paper Covid-19 test
21–30 of 31 posts
Re: India's new paper Covid-19 test
#22TL;DR:
Cost: $7
Results: 1 hour
Sensitivity: 96%
Specificity: 98%
Re: India's new paper Covid-19 test
#23$6.75 seems pretty expensive for a "ground-breaking" low cost test kit. What's the scaled cost of current tests without profit and overhead?
I don't know how much it costs in India, but I have paid around 75 Euros in France, and I think it's around 50 Euros in Germany. All of these prices which I cited for France/Germany are for those who don't have any health insurance. So reduction of cost by 8-10 times should be commended.
But for a poor Indian, 7$ is still a substantial amount of money. For a middle class Indian, it's quite affordable though.
Re: India's new paper Covid-19 test
#24Earlier quoted context omitted.
In the UK, only 2.7% of tests are returning positive results. At the end of July, this figure was 0.4%, which puts a floor on the specificity of the existing testing technology at 99.6%. If a test with only 98% specificity were used in the UK, the test would have a positive predictive value (the chance that the positive test represents a true positive result) of about 50%, far worse than existing technology.
WHere are you getting 2.7% from. In the last 24 hours in Scotland 12.8% of people tested were positive. It's been above 10%, I think, now for over two weeks.
UK wise there's about 10,000 positive cases a day from 250,000 PCR tests
E.g.
01-10-2020: 255,915 PCR tests processed, 11,988 cases dated then
Obviously the testing cockup hasn't helped, but we're still on the order of 4% of tests coming back positive
Scotland specifically hasn't had the cockup, Oct 1st was 762 cases (668 reported) from 14,316 cases, or about 5%.
Re: India's new paper Covid-19 test
#25Earlier quoted context omitted.
In the UK, only 2.7% of tests are returning positive results. At the end of July, this figure was 0.4%, which puts a floor on the specificity of the existing testing technology at 99.6%. If a test with only 98% specificity were used in the UK, the test would have a positive predictive value (the chance that the positive test represents a true positive result) of about 50%, far worse than existing technology.
WHere are you getting 2.7% from. In the last 24 hours in Scotland 12.8% of people tested were positive. It's been above 10%, I think, now for over two weeks.
https://ourworldindata.org/coronavirus-data-explorer?zoomToS...
Where are you getting 10% from???
Re: India's new paper Covid-19 test
#26Michael Mina [1] has promoted [2] the idea of $1 antigen tests as a screening tool. The idea is not that these are diagnostic (medical) tools, rather they are tools to use in schools, workplaces, sporting events. A positive antigen test would be followed up by a PCR test. The "This week in Virology" hosts had Mina on their podcast [3] and fully buy this argument for cheap tests for screening
It seems to me that this test from India is going in the same direction, though it's not clear why it's so much more expensive than what Mina describes.
[1] https://twitter.com/michaelmina_lab
Re: India's new paper Covid-19 test
#27Michael Mina [1] has promoted [2] the idea of $1 antigen tests as a screening tool. The idea is not that these are diagnostic (medical) tools, rather they are tools to use in schools, workplaces, sporting events. A positive antigen test would be followed up by a PCR test. The "This week in Virology" hosts had Mina on their podcast [3] and fully buy this argument for cheap tests for screening It seems to me that this…
> It seems to me that this test from India is going in the same direction [as the antigen rapid tests]
I think the FELUDA CRISPR/Cas9 test is more of an alternative to PCR with the potential for significantly reduced price per test. Michael Mina's $1 Lick-a-Stick self-administered rapid test is much more of a game changer. The BBC article said that "...the new test had 96% sensitivity and 98% specificity." The fact that we are talking about sensitivity without specifying the viral concentration of the test sample means that Mina's message is not getting through.
We need rapid tests that target infectious viral loads, that is, equivalent to PCR Cycle Threshold (CT) of 24 or less.
EDIT: changed $5 Lick-a-Stick to $1 - the Abbott BinaxNOW test is $5
Re: India's new paper Covid-19 test
#28Earlier quoted context omitted.
WHere are you getting 2.7% from. In the last 24 hours in Scotland 12.8% of people tested were positive. It's been above 10%, I think, now for over two weeks.
https://ourworldindata.org/coronavirus-data-explorer?zoomToS... Where are you getting 10% from???
Today's numbers from the government. They release daily.
https://www.gov.scot/publications/coronavirus-covid-19-daily...
> 697 new cases of COVID-19 reported; this is 12.8% of newly tested individuals
Is There a difference between number of people tested and number of tests carried out? Ie, do some get multiple tests?
Re: India's new paper Covid-19 test
#29Earlier quoted context omitted.
WHere are you getting 2.7% from. In the last 24 hours in Scotland 12.8% of people tested were positive. It's been above 10%, I think, now for over two weeks.
UK wise there's about 10,000 positive cases a day from 250,000 PCR tests E.g. 01-10-2020: 255,915 PCR tests processed, 11,988 cases dated then Obviously the testing cockup hasn't helped, but we're still on the order of 4% of tests coming back positive Scotland specifically hasn't had the cockup, Oct 1st was 762 cases (668 reported) from 14,316 cases, or about 5%.
See here:
https://www.gov.scot/publications/coronavirus-covid-19-daily...
697 new cases of COVID-19 reported; this is 12.8% of newly tested individuals. Are some people tested multiple times and not a their tests come back positive?
Re: India's new paper Covid-19 test
#30TL;DR: Cost: $7 Results: 1 hour Sensitivity: 96% Specificity: 98%
If these numbers hold up, this could be a game changer.