I’m currently studying ion channels from a biophysical perspective for my PhD. Beyond their fascinating role in neuronal physiology, check out the incredible chemistry and biophysics! A great introduction is MacKinnon’s Nobel lecture: https://www.nobelprize.org/uploads/2018/06/mackinnon-lecture...
The magic of ion channels in the neurons
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Re: The magic of ion channels in the neurons
#22For the Nobel winning work on this from long ago, I heartily recommend: Hodgkin, A. L. (1958). The Croonian Lecture: Ionic Movements and Electrical Activity in Giant Nerve Fibres. Biological Sciences, 148(930), 1–37. Retrieved from http://www.jstor.org/stable/83088 This contains my absolute favorite figure caption ever: A fresh and lively squid was taken out of the aquarium and immobilized by cutting the nerves conne…
Poor squid. :(
Wir müssen wissen – wir werden wissen. - Epitaph of David Hilbert
We do what we want, because we can. - GLaDOS
Take your pick of rationales, it's not gonna end well for Mr. Squid.
Re: The magic of ion channels in the neurons
#23I’m currently studying ion channels from a biophysical perspective for my PhD. Beyond their fascinating role in neuronal physiology, check out the incredible chemistry and biophysics! A great introduction is MacKinnon’s Nobel lecture: https://www.nobelprize.org/uploads/2018/06/mackinnon-lecture...
Hate to be the guy to ask this but I like to dig into conspiracy shit like: “5G is bad for our health”.
One of the theories is 4G & 5G cause mess with the electrochemical gradient and voltage gated ion channels. Given you are studying them, whats your opinions on this even being possible?
Re: The magic of ion channels in the neurons
#24Earlier quoted context omitted.
Poor squid. :(
Wir müssen wissen – wir werden wissen. - Epitaph of David Hilbert We do what we want, because we can. - GLaDOS Take your pick of rationales, it's not gonna end well for Mr. Squid.
Interestingly, the experiment in Figure 2 was to demonstrate that action potentials could be generated from isolated neurons in buffer solution just as well as they could from an exposed neuron in situ -- so the squid still dies, but it's not tortured to death.
Re: The magic of ion channels in the neurons
#25For the Nobel winning work on this from long ago, I heartily recommend: Hodgkin, A. L. (1958). The Croonian Lecture: Ionic Movements and Electrical Activity in Giant Nerve Fibres. Biological Sciences, 148(930), 1–37. Retrieved from http://www.jstor.org/stable/83088 This contains my absolute favorite figure caption ever: A fresh and lively squid was taken out of the aquarium and immobilized by cutting the nerves conne…
Somewhere in the multiverse, a scientifically curious Heptapod takes a fresh and lively humanoid from its terrarium and immobilizes it by cutting the nerves connecting the stellate ganglion...
Ender's Game series comes to mind.