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Nasal vaccine against Covid-19 prevents infection in mice

medicine.wustl.edu

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Re: Nasal vaccine against Covid-19 prevents infection in mice

#21

Post by solinent »

rzimmerman wrote: post #20
solinent wrote: post #19

Earlier quoted context omitted.

Yeah, definitely use salt water. I will mention that in the main post. You can get a product like the following which has a water preparation which should be safe: https://www.hydrasense.com/

Most of these products have a salt packet (you’re right - you definitely should not use fresh water - it will very likely cause damage) but you still need to start with distilled or properly filtered water.

You're right, I should mention not to use fresh water, though many people do use fresh water in India without problems.

This product I've pointed out is pre-mixed ocean water, it comes with the water, not just the salt packet. It's not nasal irrigation, just a spray. It's pretty effective for my sinus infections I've been exceptionally prone to.

You can also boil the water--it doesn't need to be distilled. I'm afraid distilled water may leak ions, probably shouldn't use just distilled water though I've done no research on the topic.

Based on my knowledge (science and tradition combined), you gotta use salt water, ideally the water is from a natural source and has been boiled. I don't know about distilled water. Indians have been doing this for millennia, there is a safe way to do it.

edit: Do you have a source for the fresh water being an issue? Is this an empirical result or just some theory without a study? I'm genuinely interested, I can't find any study of this. It should be easy to do as well, you could study populations in India.

Re: Nasal vaccine against Covid-19 prevents infection in mice

#22

Post by abeppu »

emmastory wrote: post #4

This is really interesting. Obviously evidence in mice is a long way away from demonstrated safety & efficacy in humans but I'll be curious to see where this one goes. If non-healthcare-professionals could be trained to administer a nasal vaccine (the way many non-hcps are able to carry and administer nasal naloxone in case of opiate overdose), it seems like it might potentially make vaccine adoption faster or more w…

Are there broader frameworks for considering the risks/benefits of training/encouraging non-healthcare-providers to administer healthcare interventions?

In something like administering naloxone or I suppose CPR training, or even just educating people about the Heimlich Maneuver, it seems like a key contributor is that an immediate response by someone on the scene of an emergency is critical. The expectation is "if you happen to encounter such an emergency, you're now able to do something to help". What you're suggesting seems qualitatively different -- proactively sending out non-healthcare-providers to administer something to people before they get sick.

And yet, if we want to administer it to billions of people quickly, maybe that will be necessary. I also wonder if that will be the bottleneck, or if producing/distributing everywhere it will be.

Re: Nasal vaccine against Covid-19 prevents infection in mice

#23

Post by newsbinator »

user_501238901 wrote: post #5

I'm very interesting if we switched to using nasal vaccines, would it help soothe out the rabid anti-vaxxers? A large part of the movement IMO stems from the fact that subconsciously, humans tend to associate long sharp needles = pain = bad

This week I made a Covid reporting site for all the regions in Bulgaria and started mentioning it in local Facebook groups.

It's staggering the number of expats here posting about Bill Gates, globalists, and a terrorist conspiracy to take over the planet by pretending Covid is a danger when it's not.

I don't think it's fear of needles or any logical aversion to something scary.

It's people who base their core beliefs on no evidence or tertiary sources, and therefore no evidence can be used to convince them otherwise.

I knew people like this are out there, but this has been like a gut punch.

Re: Nasal vaccine against Covid-19 prevents infection in mice

#24

Post by phaser »

user_501238901 wrote: post #5

I'm very interesting if we switched to using nasal vaccines, would it help soothe out the rabid anti-vaxxers? A large part of the movement IMO stems from the fact that subconsciously, humans tend to associate long sharp needles = pain = bad

You would think your logic makes sense in an anti-vaxxer, but there's many components to their ideology. I believe they are suspicious to anything that's mandatory. I presume this nasal vaccine will be mandatory (at least here in Chile government already determined when the vaccine arrives it will be obligation in risk groups) and would conform to their worldview of evil globalists killing the population for their kids to inherit an empty world.

Re: Nasal vaccine against Covid-19 prevents infection in mice

#25

Post by marketgod »

solinent wrote: post #15
jbd28 wrote: post #13

Earlier quoted context omitted.

That viral email was complete junk from early in the pandemic

It wasn't a viral email--it was a one hour podcast on Youtube. I can post a link if you'd like.

It would help make your argument. I'd like to hear about nasal rinse making you more healthy. All I see is a Joe Rogan podcast, if that's what you are referring to?

Re: Nasal vaccine against Covid-19 prevents infection in mice

#30

Post by solinent »

marketgod wrote: post #25
solinent wrote: post #15

Earlier quoted context omitted.

It wasn't a viral email--it was a one hour podcast on Youtube. I can post a link if you'd like.

It would help make your argument. I'd like to hear about nasal rinse making you more healthy. All I see is a Joe Rogan podcast, if that's what you are referring to?

That's the one. The nasal rinse stuff comes from studies I've read years ago, if you want I can dig them up.

Sorry, this last little week has been pretty crazy, no time to check back here.

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