This is such mind-blowing success, it makes me contemplate switching fields. Is it reasonably feasible to switch from IT to Biotech/Medical Research in the mid thirties? I had a friend with Fukutin-related limb-girdle muscular dystrophy R13 and am wondering if CRISPR could be the solution for her.
Three people with inherited diseases successfully treated with CRISPR
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Re: Three people with inherited diseases successfully treated with CRISPR
#22Definition of disease: Resulting from a pathophysiological response to external or internal factors.
Definition of disorder: A disruption of the disease to the normal or regular functions in the body or a part of the body.
Edit: I have it myself (and my kids do too), and I often correct people on this. Since I rather have a disorder than a disease:)
Re: Three people with inherited diseases successfully treated with CRISPR
#23Re: Three people with inherited diseases successfully treated with CRISPR
#24But will the drug approval agencies allow genetically engineered therapies for anything disruptive? For example, they've been blocking the caries vaccine for decades.
Re: Three people with inherited diseases successfully treated with CRISPR
#25This is such mind-blowing success, it makes me contemplate switching fields. Is it reasonably feasible to switch from IT to Biotech/Medical Research in the mid thirties? I had a friend with Fukutin-related limb-girdle muscular dystrophy R13 and am wondering if CRISPR could be the solution for her.
Anecdotal, but my cousin did exactly this. I will note, he is probably the most exceptional person I known of, beyond those classic geniuses everyone knows.
Re: Three people with inherited diseases successfully treated with CRISPR
#26It's interesting that they did not just undo the inherited disease. I assumed that, especially with Sickle Cell where we have a good understanding of how it works, they would go into Chromosome 11 and put it back how it "should" be with CRISPR. But instead they apply a workaround, ensuring continued fetal haemoglobin production. The article does not mention whether that's because putting Chromosome 11 back with CRISP…
Re: Three people with inherited diseases successfully treated with CRISPR
#27This is such mind-blowing success, it makes me contemplate switching fields. Is it reasonably feasible to switch from IT to Biotech/Medical Research in the mid thirties? I had a friend with Fukutin-related limb-girdle muscular dystrophy R13 and am wondering if CRISPR could be the solution for her.
Anyone knows how to get into the field?
Re: Three people with inherited diseases successfully treated with CRISPR
#28Earlier quoted context omitted.
Anecdotal, but my cousin did exactly this. I will note, he is probably the most exceptional person I known of, beyond those classic geniuses everyone knows.
Interesting, can you give a bit more details what exactly his path was?
Re: Three people with inherited diseases successfully treated with CRISPR
#29Earlier quoted context omitted.
Anyone knows how to get into the field?
As an other commenter wrote, if you know some software engineering, you are already valuable to all biotech companies, so it's probably better to go there as an engineer first and pick up the biology on the side than to go back to school and waste 5 years of your life without providing real value.
Re: Three people with inherited diseases successfully treated with CRISPR
#30But will the drug approval agencies allow genetically engineered therapies for anything disruptive? For example, they've been blocking the caries vaccine for decades.
https://www.nytimes.com/2019/10/09/health/mila-makovec-drug....