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#21
post #2

The repeated recommendation to use a drug which has not been properly tested by the president of the most powerful nation on this planet seems inappropriate to me.

When did Trump recommend that people self-medicate chloroquine? Even the CNN article trying to pin this on him only quoted him as saying that he was working with the FDA to make it available via prescription for this treatment.

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#22
I wasn't able to find a reliable source on short notice, but the ones I found indicate a therapeutic index of around 4-8 for chloroquine. The therapeutic index is the ratio between the dose that is effective and the lethal dose. So in this case if you take 4-8 times the dose that actually works you're in the range where it could kill you.

I'd be really interested in more robust sources on this. But from the bits I've seen so far, this drug doesn't have as much distance between the effective dose and the lethal dose as you'd like for something that people are likely to self-administer now.

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#24
post #2

The repeated recommendation to use a drug which has not been properly tested by the president of the most powerful nation on this planet seems inappropriate to me.

I'm inclined to argue about the title "most powerful nation on this planet". It's a nice tagline, but the metrics for which it applies are narrowing rapidly.

But still, let this be a lesson to those who would follow bad leaders to their own demise; or rather, let it be a lesson to their offspring who watch them follow the bad leaders.

I suspect humanity follows cycles of enlightenment, complacency, and self-destruction (or irrelevance, which is equally damning depending on the individual). We appear to be between stage 2 and 3 at this point.

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#25
A relevant data point. I don't think this is a good way to share public health information.

@realdonaldtrump 7:13 AM - 21 Mar 2020

HYDROXYCHLOROQUINE & AZITHROMYCIN, taken together, have a real chance to be one of the biggest game changers in the history of medicine. The FDA has moved mountains - Thank You! Hopefully they will BOTH (H works better with A, International Journal of Antimicrobial Agents).....

....be put in use IMMEDIATELY. PEOPLE ARE DYING, MOVE FAST, and GOD BLESS EVERYONE! @US_FDA @SteveFDA @CDCgov @DHSgov

https://twitter.com/realdonaldtrump/status/12413672399007785...

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#26
post #2

The repeated recommendation to use a drug which has not been properly tested by the president of the most powerful nation on this planet seems inappropriate to me.

[deleted]

Re: undefined

#28
A bit more info: https://www.nbcnews.com/health/health-news/man-dies-after-in...

Also happening in Nigeria: https://www.democracynow.org/2020/3/23/headlines/two_nigeria...

Note that there doesn't appear to be any evidence yet that chloroquine is effective in COVID-19 treatment. So far it has been studied only for other types of coronavirus.

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#29

Chloroquine is safe when administered by a doctor. It's also easy to overdose if you don't know what you're doing. I'd hate to see people spread information about how dangerous Chloroquine is when it may be very useful treatment during this pandemic.

From the page linked in the article: "A man has died and his wife is under critical care after the couple, both in their 60s, ingested chloroquine phosphate, an additive commonly used at aquariums to clean fish tanks.". Did he literally just consume fish tank cleaner? That seems like a really easy way to mess up dosing.

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#30
When trump was talking chloroquine, were we supposed to take him literally, or seriously? I don't know when I am supposed to do one or the other.
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