Detroit: High crime, cold weather, ridiculous tax structure inside city limits, no outdoor activities... just pick some podunk town in Texas, you'll be better off all around.
Great - where else? If we're going to pick our ideal city, what should it be? Maybe podunk Texas isn't going to have the best internet service. Who does, within the list of economically thirsty locations? That's the underlying question: What city has cheap housing, good infrastructure and is friendly to tech startups?
Pittsburgh is pretty much all of those. Insanely cheap housing (I pay $400 for a 2br - with no roommate, just me.) Access to the best young talent around (Pitt, Carnegie Mellon, + numerous other schools). Relatively low crime rate, and it's named the best city to live in fairly often.
The only downside is the weather, which isn't that bad in the winter -- certainly much better than Detroit or Boston.