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Medications that change who we are

bbc.com

21–30 of 289 posts

Re: Medications that change who we are

#22

Medication is just a tool, it must be used with care and intelligence.

it is a tool. i don’t believe it’s a matter of care or intelligence. it’s just hard to synthesize something that targets one thing we don’t like (cholesterol in this case). sometimes it goes as far as not really understanding the underlying mechanism through which the drug actually works - i would say most times the full interaction of the drugs are not fully understood. if you add the desire to take a pill and just fix whatever issue you have i can see how, on a large scale, this can be problematic

Re: Medications that change who we are

#23
“Then one day, she was chatting to a cholesterol expert about the potential link in the hallway at her work, when he brushed it off as obviously nonsense. “And I said ‘how do we know that?’,” she says.”

These are our “experts”, brushing off things about which they have no clue.

“How are all these medications affecting our brains? And should there be warnings on packets?”

Yet another warning in a list that makes people's eyes glaze over is not going to do much good. Additionally, people have a difficult time relating to just how bad these effects can really be. People also tend to overestimate their abilities to perceive the effects and endeavor to address them.

“But Golomb’s most unsettling discovery isn’t so much the impact that ordinary drugs can have on who we are – it’s the lack of interest in uncovering it. “There’s much more of an emphasis on things that doctors can easily measure,” she says,”

And what is it about medications that makes people willing to connect these dots? Money and a willingness to not want to know and even to deny what is known. The chemical industry is very good at this and we've known about that for a very long time. There are numerous studies that have found these same associations with various chemical products from artificial food colorings to laundry chemicals and more, with effects that include anxiety, depression, and rage. The ubiquity of chemicals with unknown physiological and psychological is staggering. It's gotten to the point where we can barely socialize without being inundated with the 21st version of passive smoking. People and places can't exist without dousing themselves and their spaces with chemical crap that also includes air "fresheners", candles, essential oils, etc. Road rage, infertility, anxiety, depression . . . all these psychological phenomena that have risen along with the public test lab that is our world. And chemical companies are using the tobacco industry's template of doubt and denial along with decades of honing the craft.

“But in order to minimise any undesirable effects and get the most out of the staggering quantities of medications that we all take each day, Mischkowski reiterates that we need to know more. Because at the moment, he says, how they are affecting the behaviour of individuals – and even entire societies – is largely a mystery.”

It's true. And if it's a problem for medications that are presumably scrutinized, what do we think is the case with the 10s of thousands of chemicals that are basically tested using the “honor system” of industry testing its own products for safety? These chemicals are not tested singly, nevermind in the near limitless combinations in which they exist in our daily lives.

“At this point it’s worth pointing out that no one is arguing that people should stop taking their medication. Despite their subtle effects on the brain, antidepressants have been shown to help prevent suicides, cholesterol-lowering drugs save tens of thousands of lives every year, and paracetamol is on the World Health Organisation’s list of essential drugs because of its ability to relieve pain. But it is important that people are informed about any potential psychological side-effects.”

And every one of these articles will include this boilerplate rationalization that's a lot more complicated – and different – than this.

Re: Medications that change who we are

#24
post #8

Probably all that's going through the stomach has one effect or another... Ever watched kids behaviour before and after sugary and non-sugary meals?

https://www.livescience.com/55754-does-sugar-make-kids-hyper... There seem to be a bunch of studies indicating that it is not the sugar that affects the behavior

That link does little to disprove that sugar isn't the culprit.

And anecdotally, both my partner and I can recognize adverse psychological effects in myself after I consume too many high-glycemic carbs (ie, sugar).

Re: Medications that change who we are

#25

An easy but not glamorous course of action to prevent this from happening on a large scale is flushing the notion that taking a pill for everything everytime is A-OK out of Western culture. The average American is on ~1 prescribed pain killer and usually has access to several other over the counter opioids. People take incredibly potent whatevers against the mildest allergies to prevent having reddish eyes. A pill to…

What "other over the counter opioids"?

Re: Medications that change who we are

#26

I am happy to accept that mass prescription of drugs will have unexpected side-effects, and the cholesterol/ anger / violence link seems plausible. My question is has anyone studied voting intentions with this as well?

You mean studied whether mass prescription of drugs has an effect on how the people taking them vote?

Re: Medications that change who we are

#27

Tangentially (and anecdotally), not long ago I seem to have contracted what seems like a flu (or the like), and I remember feeling very healthy, social and unusually well—almost high—most of the day right until my brain went foggy and fever started. In hindsight, I did not behave quite like myself that day, especially considering I felt somewhat overworked the preceding week. This prompted me to first draw the analog…

A month ago I had an especially good workout then a few hours later the dengue fever that was incubating hit.

Re: Medications that change who we are

#28
post #2

I’d be curious to hear the experiences of people who take/have taken some of these drugs such as L-dopa. With alcohol, I feel different but I don’t feel like a different person. Is it like that, or is there a larger feeing of difference?

For a lot of folks with epilepsy, this is nothing new. Plenty of medications that treat epilepsy are known to induce changes in mood, mental state, etc.

Probably the biggest one is levetiracetam (also known as Keppra). If you read the warning label, it says it can induce "mood changes", which is a euphemistic way of saying "it can turn you into an uncontrollable rage monster".

I've been there. Whatever you think you know about getting ticked off, you haven't felt angry until you've felt it on Keppra. There is no gradation of anger-- no "subtly annoyed", no "getting ticked off", no "this is really getting me angry". Just "zero" and "Incredible Hulk on a bad day". The stuff that annoys you may not be anything that annoyed you in the past, but now it's something that makes you want to bash somebody's skull against the pavement until it goes soft. And there is no warning, no ramp-up-- you just suddenly find yourself enraged beyond all human comprehension, and you're doing everything you can just to restrict yourself to yelling incoherently instead of resorting to physical violence.

There's even a cute nickname for this whole horror show: "Kepprage".

I'm off levetiracetam now (onto lamotrigine, which is also prescribed as an antidepressant). But it scared me pretty badly. I genuinely fear getting angry now-- because I worry that I'm going to wind up back where I was. I was single when I was on Keppra, but I'm in a relationship now-- it scares me to think what I might do if I ever get back to Kepprage levels of anger, because it could easily cost me my partner.

So, to your question: was I a different person on Keppra? I mean, I still responded to my name and worked the same job and had the same favorite foods and such. But I was a lot angrier, I was getting angry all the time, and there was no off switch. It's a valid philosophical question as to whether that makes me a "a different person". Looking to your example, consider that feeling that you have on alcohol, and its assorted side effects and behavioral changes. Now imagine that you were stuck in that mode, 24/7. Would you be "a different person"?

Re: Medications that change who we are

#29

An easy but not glamorous course of action to prevent this from happening on a large scale is flushing the notion that taking a pill for everything everytime is A-OK out of Western culture. The average American is on ~1 prescribed pain killer and usually has access to several other over the counter opioids. People take incredibly potent whatevers against the mildest allergies to prevent having reddish eyes. A pill to…

That's not Western, but American. In Europe much weaker painkillers are prescribed due to risk of addiction, and in places like germany a lot of placebo (= overpriced homeopatic bullshit)

Re: Medications that change who we are

#30

Tangentially (and anecdotally), not long ago I seem to have contracted what seems like a flu (or the like), and I remember feeling very healthy, social and unusually well—almost high—most of the day right until my brain went foggy and fever started. In hindsight, I did not behave quite like myself that day, especially considering I felt somewhat overworked the preceding week. This prompted me to first draw the analog…

A month ago I had an especially good workout then a few hours later the dengue fever that was incubating hit.

Similarly, I've learned to avoid running when I begin to feel any symptoms of a sinus infection or head cold.

Time and time again, I wake the next day will the full-blown illness.

Instead, a little rest goes a long way in letting my body heal itself.

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