Live data from Hacker News

Neural correlates of the DMT experience assessed with multivariate EEG

nature.com

21–30 of 206 posts

Re: Neural correlates of the DMT experience assessed with multivariate EEG

#21

Earlier quoted context omitted.

Agreed that it's interesting nonetheless. I've been "joking" with my friends that I want to take a trip to Costa Rica to do Ayahuasca with them. The "story" of how Ayahuasca came to be is quite fascinating: Ayahuasca, the drink, is actually comprised of two plant-based ingredients. One of the ingredients supplies the "DMT" portion, but the effects would last a very short time (something like 20 seconds to a couple mi…

I heard an alternative is "yopo" where they blow it up each others nose via a straw and I don't think that needs an MAOI.

DMT can also be smoked or injected, the reason why oral consumption requires the MAOI is because it prevents an enzyme in your liver* from destroying the DMT.

The effects of smoking it are only ~15 minutes long from what I've heard. Blowing it up each others nose can't be that common recreationally at least given that there's much easier ways to consume it (smoking it).

Re: Neural correlates of the DMT experience assessed with multivariate EEG

#23

> The present study’s findings significantly advance our understanding of the brain basis of one of the most unusual and intense altered states of consciousness known – previously likened to dreaming... This study does not "find that DMT produces a dream-like state"; that was already well established. This study identifies the subtle brain activity that differentiates the hallucinations from dreaming. > This experien…

I've tried explaining this to people who've never tried psychedelics. It is unlike any other substance I've ever tried (a lot of them, FWIW) in that it leaves you with lasting impressions. Some things I gleaned tripping have stuck with me to this day. It has changed me for the better.

Re: Neural correlates of the DMT experience assessed with multivariate EEG

#24

I really want to try DMT but terrified to do that without professional help nearby e.g. on an Ayahuasca retreat. I have experienced both LSD and shrooms but have heard DMT is on another level.

I don't see how DMT can be on another level. LSD is already in another dimension. How much more freaky can it get?

Re: Neural correlates of the DMT experience assessed with multivariate EEG

#25

Has anyone ever tripped on Ayahuasca/DMT and afterwards embraced the thought that everything they experienced was simply a hallucination or dream that they cannot actually integrate back into their regular, sober, waking life?

Who's to say that waking consciousness isn't just a hallucination or dream that can't be integrated into their actual, transcendent, spiritual life?

Re: Neural correlates of the DMT experience assessed with multivariate EEG

#26
post #5

Earlier quoted context omitted.

“My brain is only a receiver, in the Universe there is a core from which we obtain knowledge, strength and inspiration. I have not penetrated into the secrets of this core, but I know that it exists.” -Nikola Tesla

Brilliant man, but he also believed in the luminiferous aether.

so did Plato and Aristotle, so why the "but"

Re: Neural correlates of the DMT experience assessed with multivariate EEG

#27

I really want to try DMT but terrified to do that without professional help nearby e.g. on an Ayahuasca retreat. I have experienced both LSD and shrooms but have heard DMT is on another level.

Depends on the dose. Personally I've had stronger trips with LSD and mushrooms. Also in all ceremonies I've participated you get to drink ayahuasca a number of times so you can judge if you want more or not.

In a ceremony I saw a woman drink ayahuasca just once and she had a much stronger trip that the rest of us, but this is uncommon.

Re: Neural correlates of the DMT experience assessed with multivariate EEG

#29
post #7

Title is inaccurate, this study used intravenous DMT, as opposed to Ayahuasca which is a oral concoction of DMT and an MAOI. Interesting nonetheless.

Agreed that it's interesting nonetheless. I've been "joking" with my friends that I want to take a trip to Costa Rica to do Ayahuasca with them. The "story" of how Ayahuasca came to be is quite fascinating: Ayahuasca, the drink, is actually comprised of two plant-based ingredients. One of the ingredients supplies the "DMT" portion, but the effects would last a very short time (something like 20 seconds to a couple mi…

My guess is they already knew about the MAOI to at least some degree and noticed that the effects of other plants were amplified when combining them. So when they found the DMT plant, someone figured it'd be worth seeing what happens when they combine them.

If it's true that the DMT plant has no psychoactive effects when taken alone, maybe someone had already had a routine of taking the MAOI and just eating most plants they came across, to see what would happen.

Re: Neural correlates of the DMT experience assessed with multivariate EEG

#30

> The present study’s findings significantly advance our understanding of the brain basis of one of the most unusual and intense altered states of consciousness known – previously likened to dreaming... This study does not "find that DMT produces a dream-like state"; that was already well established. This study identifies the subtle brain activity that differentiates the hallucinations from dreaming. > This experien…

Contrary to popular opinion I haven't found DMT to be that much different than any other psychedelic drug when comparing equivalent doses. Sure it's true that while high on the drug it creates experiences that feel real, but that's true of dreaming too, isn't it? It's not obvious that it wasn't real until it's over. And similarly I have had the same feeling from high doses of "plain old" psychedelics.
Post reply on HN