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Alarming surge in drug-resistant HIV uncovered

nature.com

21–30 of 237 posts

Re: Alarming surge in drug-resistant HIV uncovered

#21
post #5

Earlier quoted context omitted.

It’s insane that it is $1400/month out of pocket, and if you have a high deductible plan you’d still be paying $6k+ potentially before it’s covered.

WHAT!? Here in Germany, my PrEP costs me €40 per month, and I only have to pay that because it’s one of the rare things that insurance doesn’t cover here.

In Australia its around $40 a month, so slightly less. Worth it!!! Still, too expensive for some people. Should be free.

Re: Alarming surge in drug-resistant HIV uncovered

#23
post #22

Probably because homosexuality doesn't fit their 19th century worldview

Or some people take it and engage in risky sexual behavior because they're now on it. I know more than a few people like that. Not everyone is a backwards hick, you're just virtue signalling.

Re: Alarming surge in drug-resistant HIV uncovered

#24
post #22

Probably because homosexuality doesn't fit their 19th century worldview

Or some people take it and engage in risky sexual behavior because they're now on it. I know more than a few people like that. Not everyone is a backwards hick, you're just virtue signalling.

UpToDate.com:

STI incidence among MSM using PrEP Men who have sex with men (MSM), particularly those who have indications for pre-exposure prophylaxis against HIV (PrEP), are at high risk for sexually transmitted infections (STI). In a study of nearly 3000 MSM in Australia who were initiating PrEP, the incidence of new chlamydia, gonorrhea, or syphilis over the subsequent year was 92 cases per 100 person-years [2]. Nearly half of the participants were diagnosed with an STI during the study period, with 25 percent of participants accounting for 75 percent of all STIs diagnosed; the risk of STI was proportional to the number of sexual partners and frequency of group sex. These data highlight the importance of frequent STI screening for MSM using PrEP.

2. Traeger MW, Cornelisse VJ, Asselin J, et al. Association of HIV Preexposure Prophylaxis With Incidence of Sexually Transmitted Infections Among Individuals at High Risk of HIV Infection. JAMA 2019; 321:1380.

Re: Alarming surge in drug-resistant HIV uncovered

#25
post #22

Probably because homosexuality doesn't fit their 19th century worldview

Or some people take it and engage in risky sexual behavior because they're now on it. I know more than a few people like that. Not everyone is a backwards hick, you're just virtue signalling.

Oh - thanks! I’m glad someone from the 19th century is here to explain the worldview in question.

Re: Alarming surge in drug-resistant HIV uncovered

#26
post #10

I always felt like the only way you can eliminate the spread of a highly adaptive std is to develop a low barrier on-the-spot test administered just before intercourse at the latest or some point reasonably earlier in a date or whatever. This would still fail under the dormancy period viruses assume but it should improve the odds I'd imagine for those connected in one way or another to promiscuous sexual networks.

That's not a bad idea, but how does liability play out on a defective test, or a test used in a manner other than directed? Would you bet the rest of your life on a casual test like that?

>Would you bet the rest of your life on a casual test like that?

On an individual level, this doesn't guarantee much, but on a population level this could provide a huge benefit. You yourself might not feel confident based on the test, but it would likely severely limit the spread of STDs (as long as treatment is available and accessible).

Re: Alarming surge in drug-resistant HIV uncovered

#27
post #18
post #14

Earlier quoted context omitted.

PrEP is hard to get, my doctor outright refused to prescribe it to me, they said they were not comfortable doing so

Did they give a reason for their discomfort?

Lack of familiarity with the drugs mostly.

Re: Alarming surge in drug-resistant HIV uncovered

#28
post #14

Earlier quoted context omitted.

PrEP is hard to get, my doctor outright refused to prescribe it to me, they said they were not comfortable doing so

The get a new doctor, one who values your health more than their antiquated morals.

Getting a doctor takes time, something I'm woefully short on.

Re: Alarming surge in drug-resistant HIV uncovered

#29
post #5

Earlier quoted context omitted.

It’s insane that it is $1400/month out of pocket, and if you have a high deductible plan you’d still be paying $6k+ potentially before it’s covered.

WHAT!? Here in Germany, my PrEP costs me €40 per month, and I only have to pay that because it’s one of the rare things that insurance doesn’t cover here.

yeah, shocking. if you have diabetes or a thyroid issue or hiv or really any chronic disease that requires medication you are out 12k a year easy, 6 for your insurance premiums and 6 for the deductible and copays. if you are broke there are some provisions, but if you are above the poverty line you gotta pay.

Re: Alarming surge in drug-resistant HIV uncovered

#30

Earlier quoted context omitted.

That's not a bad idea, but how does liability play out on a defective test, or a test used in a manner other than directed? Would you bet the rest of your life on a casual test like that?

> Would you bet the rest of your life on a casual test like that? On an individual level, this doesn't guarantee much, but on a population level this could provide a huge benefit. You yourself might not feel confident based on the test, but it would likely severely limit the spread of STDs (as long as treatment is available and accessible).

Even if treatment isn't available.

The main benifit of a bed-side test isn't that it informs the person who is infected. It is that it informs the person who is not infected.

Currently, most people who ask about STD status just take their partners word. Maybe a particuarly paranoid person will ask to see actual lab results, which could reasonably be months or years old at best (how often do you expect people to get tested?) or maliciously forged at worst (hopefully rare enough to be irrelevant at the population level).

With a bedside test, you get up to date information (subject to the quality of the test) on if you are about to get exposed, and can avoid the exposure if necessary.

There is still the cultural issue of needing to test your partner before an interaction, would might come across as prohibitively offensive.

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