Isn't this similar to the Nuitka project? http://nuitka.net/ Nuitka has fantastic Python 3 support (up to 3.7 currently).
Pythran main aim is to be fast, and to achieve this they're willing to only support a small subset of python.
As Nuitka's performance gets better and Pythran starts to support more and more of python, perhaps they'll converge at some point in the future.