This is the email version of when Telemarketers call me and ask to "speak with someone in the house between the ages for x-y" to which I say, "sure just a sec", then put the phone down on the desk and walk away.
One other thing I did was ported my landline over to callcentric.com, where for $3.50/month or so, I can 'firewall' all calls coming to that number, making it safe to give out to anyone. Their call treatments allow me to, by specific number or patterns (800*), drop, send to voicemail, play the "number disconnected" tone, forward, etc. It's great - no more calls I don't want.