For IDE support, I'm totally in love with PyCharm and been using it for years, first community and then I upgraded to Pro for Cython support. PyCharm Pro has syntax highlighting and does inspections (linting) on Cython code, so it's a wonderful tool, totally worth its price.
Can't really recommend any other IDE because I haven't used another one for over 4 years, though a friend uses (loves) Sublime Text and has high praise for it too. It has Cython syntax support, but there's really no linter for Cython -- what's more, you may have to turn off warnings if you're using a Python linter because it'll complain about cdefs and such.
As for the day to day use, I don't do that much Cython really, ocassionally to speed things up. I start from a Python function, then make a .pyx (or bunch of .pyxes) files and replicate what's needed. Compile, load both versions (Py and Cy) and compare outputs and speed from IPython or with benchmark scripts.
I did use a lot the Cython functionality to create the HTML view of the source source at the beggnining, though you get the hang of what transpiles well with time and use it less and less. Still, sometimes it's useful.