Alt -> Control
Windows-key and Menu Key -> Alt
Control keys -> Windows key
So without having ever seen a Symbolics keyboard and without knowing the history behind emacs keyboard layout I remapped my keyboard so that I had very quick access to Control and Alt (= Meta) keys.
On my Macbook it's not that easy. I could remap the Command key to become a Control key, but many Mac shortcuts heavily rely on the Command key. So that's no option.