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Magic mushrooms found to lift severe depression in clinical trial

theguardian.com

21–30 of 173 posts

Re: Magic mushrooms found to lift severe depression in clinical trial

#21

It's great to see the advances in research that are being done around Psilocybin, MDMA, and Ketamine as the results that are coming out look incredibly promising. That being said, godDAMN how in the hell is anyone ever going to take studies like this seriously when they're being reported as "Magic Mushrooms" in Scientific American of all places? This isn't raver kiddies eating dried who-knows-what out of ziplock bags…

A return to alchemy...

Re: Magic mushrooms found to lift severe depression in clinical trial

#22
post #14
post #12

Says more about how poorly the brain is understood than anything else. Also, very possible that the measures that were take to keep people "safe" were a factor. Anyone know if there was a control group given the same treatment (double blind) - but with a placebo? __________ EDIT: Direct link to the related research paper: Psilocybin for treatment-resistant depression: a feasibility study http://www.thelancet.com/pb/a…

I wonder what could be given as placebo tho. It is not like you do not notice you are tripping.

> I wonder what could be given as placebo tho.

I don't know about this trial specifically, but they usually use something like methylphenidate or nicotene.

Re: Magic mushrooms found to lift severe depression in clinical trial

#23

When I am finishing a mushroom experience I usually have overwhelming feelings of love and am excited to start the next day. My brain is racing with all the possibilities of life and ways I can make things better for myself. People should be coached in how to have a good mushroom experience and what to expect. Nature + fresh fruit + good music + comfy place to sleep has always been a winning combination for me.

That's interesting. I've had the opposite experience when ending my psychedelic experiences. I find that I get overly critical in my introspection and pick apart every perceived flaw, leaving me in a raw and negative mental state.

Instead of leaving me feeling refreshed I am drained and dread the idea of going back to being "normal" where I become blind to those obvious flaws and complacent with living a sub-par life.

Re: Magic mushrooms found to lift severe depression in clinical trial

#24
post #14
post #12

Says more about how poorly the brain is understood than anything else. Also, very possible that the measures that were take to keep people "safe" were a factor. Anyone know if there was a control group given the same treatment (double blind) - but with a placebo? __________ EDIT: Direct link to the related research paper: Psilocybin for treatment-resistant depression: a feasibility study http://www.thelancet.com/pb/a…

I wonder what could be given as placebo tho. It is not like you do not notice you are tripping.

Not true, you'd be surprised what the mind is able to do on its own. Besides both groups should be exposed to "trippy" stimulus, which for the naive would be enough. Seen non-alcoholic experiments where the unknowning participants showed ALL the signs of having had alcohol; that is until they were told they were not drinking alcohol.

Re: Magic mushrooms found to lift severe depression in clinical trial

#25
> It took 32 months between having the grant awarded and dosing the first patient, says Nutt. By comparison, it took six months “to get through the machinations” for his team’s previous studies using the equally illegal drugs LSD and MDMA, he says.

I thought we were making progress...

Re: Magic mushrooms found to lift severe depression in clinical trial

#27

It's great to see the advances in research that are being done around Psilocybin, MDMA, and Ketamine as the results that are coming out look incredibly promising. That being said, godDAMN how in the hell is anyone ever going to take studies like this seriously when they're being reported as "Magic Mushrooms" in Scientific American of all places? This isn't raver kiddies eating dried who-knows-what out of ziplock bags…

Whenever pot-culture words come up in "reporting" about medical treatments I immediately tune out. That's not to say there aren't any potential health benefits but "toking herb" (or whatever) isn't the best way to present them to people who still demonize it.

Re: Magic mushrooms found to lift severe depression in clinical trial

#28

When I am finishing a mushroom experience I usually have overwhelming feelings of love and am excited to start the next day. My brain is racing with all the possibilities of life and ways I can make things better for myself. People should be coached in how to have a good mushroom experience and what to expect. Nature + fresh fruit + good music + comfy place to sleep has always been a winning combination for me.

I recommend a shaman to guide you through the journey. Someone who has been there before. Otherwise, you'll spend way too much time looping around one topic or idea. let them give you the hints to jump loops and go beyond.

<3

Re: Magic mushrooms found to lift severe depression in clinical trial

#29

When I am finishing a mushroom experience I usually have overwhelming feelings of love and am excited to start the next day. My brain is racing with all the possibilities of life and ways I can make things better for myself. People should be coached in how to have a good mushroom experience and what to expect. Nature + fresh fruit + good music + comfy place to sleep has always been a winning combination for me.

I'd definitely recommend doing this only with someone who has experience and is reasonable. On one of my last camping trips I saw two girls doing mushrooms which ended with one of them running around naked for hours screaming for help and attacking people she thought were demons. This only ended when a park ranger arrested her after a chase through the bushes. Her friend was just watching and smiling.

I am not opposed to drugs but you should know what you are getting into.

Re: Magic mushrooms found to lift severe depression in clinical trial

#30

It's great to see the advances in research that are being done around Psilocybin, MDMA, and Ketamine as the results that are coming out look incredibly promising. That being said, godDAMN how in the hell is anyone ever going to take studies like this seriously when they're being reported as "Magic Mushrooms" in Scientific American of all places? This isn't raver kiddies eating dried who-knows-what out of ziplock bags…

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