Is there a reason why the file size has exploded? react.min.js is now 145.4kb. For comparioson, angular.min.js is 155.2kb. One of React's biggest selling points was that it was much smaller than Angular/Ember/Backbone etc, but I'm not sure that argument can be leveraged anymore. I think React is a culmination of some great ideas, but in my view this is a big step back. Especially since Angular/Ember/etc. offer a lot…
(Also note that growing framework code can reduce your app code size overall; I don't want to make specific claims about React but at Facebook we often see code size increase when 10 people all try to avoid importing the same module and end up reimplementing 20% of it 10 times and increasing the overall size.)
I haven't looked lately at the biggest contributors to React's file size. We're certainly willing to try to modularize more when it makes sense, but we do that more with an eye towards developer flexibility rather than runtime efficiency.