One application comes to mind for this: watch for new screenshots (assuming they automatically get put into a directory for Fallout 4 screenshots) and add the in-world coordinates to the EXIF data.
- a fitbit (pipbit?) for Fallout, track how many km/miles ran/walked, how many km while carrying how much kg of equipment, theoretical calories lost
- since it seems to synchronize stats and inventory, you can map where the player killed most enemies/took most stimpaks so you can get a heatmap of enemy-rich zones and rank them by difficulty - divide killed enemies by health lost (or used stimpaks)
- there are sites like fallout4map.com which track the location of unique and hardcoded items, you can automate this now