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Room temperature quantum transfer in biological systems

nature.com

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Re: Room temperature quantum transfer in biological systems

#21
post #9

Earlier quoted context omitted.

That work is highly speculative (I've studied, but not as my primary work, enzyme kinetics and reaction mechanisms). Finding holes in transition state theory isn't hard and I don't see that it's necessary to invoke tunneling protons to come up with better theories. Even the physical experiments cited in the Ball article, are pretty speculative, and aren't accepted by the mainstream. I find it pretty amusing, because…

The ammonia maser uses proton tunnelling.. the guy who invented that also got "laughed out of the room". Well, it's probably a different pressure / temperature than enzyme kinetics, but those physicists, they like to own the quantum and not let anyone else have it. :-)

When I studied undergraduate quantum mechanics (physics dept, many years ago) one of our homework problems involved oscillation of the ammonia atom. Ie, the three hydrogen atoms form a triangle, and the nitrogen atom is in a superposition of states above or below the hydrogen plane.

Iirc, given some estimate of the relative potential energy barrier formed by the hydrogen atoms, we showed that the nitrogen atom would effectively oscillate between the up and down states and calculated the frequency of oscillation.

Re: Room temperature quantum transfer in biological systems

#22
post #2

You should watch this before looking at the article: http://www.ted.com/talks/jim_al_khalili_how_quantum_biology_...

Brilliant talk, more:

Jim Al-Khalili's Quantum Biology Conference, Videos of talks, IAS Surrey 2012

http://www.ias.surrey.ac.uk/workshops/quantumbiology/

BBC 4 is currently airing Jim's 4 part Science Documentary on Biology exploiting Quantum Weirdness.

http://www.bbc.co.uk/iplayer/episode/b04v85cj/the-secrets-of...

Re: Room temperature quantum transfer in biological systems

#23
post #9

Earlier quoted context omitted.

That work is highly speculative (I've studied, but not as my primary work, enzyme kinetics and reaction mechanisms). Finding holes in transition state theory isn't hard and I don't see that it's necessary to invoke tunneling protons to come up with better theories. Even the physical experiments cited in the Ball article, are pretty speculative, and aren't accepted by the mainstream. I find it pretty amusing, because…

And i had a committee member forbid me from including quantum effects in the modeling of my enzyme. He said it was "too speculative". All science is speculative, until it isn't. You would be well served to reduce your "highly speculative" filters. That is, continue to propose your interesting new chains of causation. If there were braver people than me (which shouldn't be hard) then perhaps understanding enzyme mecha…

Roger Scrunton, Manchester Uni, Quantum Effects in Biological Catalysis

https://www.youtube.com/watch?v=SnxmHlbtJDI

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