191–200 of 456 posts
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> We all know about opiates No, I do not think we do, because it causes none of the side-effects associated with NSAIDs, and it is even safer than acetaminophen, i.e. there is no risk of hepatotoxicity whatsoever. The only side-effect is euphoria. Please do not mention respiratory depression here, that is a non-issue, it matters as so much as liver failure matters with acetaminophen overdoses. Opiates are safer than…
They do cause constipation
ugh, i am allergic to ibuprofen and aspirin (all NSAIDs to be precise). tylenol is my only OTC option.
You’re not going to become autistic all of sudden after taking Tylenol. The claim is that it effects the fetus during pregnancy
More likely to take painkillers + more likely to get your child assessed for autism = observed (tiny) correlation, even in the absence of any causation.
There is research correlating autism and mothers taking certain medications (painkillers, antidepressants). Since autism is hereditary, there is a significant chance that these mothers are autistic too. Autistic people have a vastly high risk of depression, and often have unusual pain thresholds, requiring more painkillers. I would not be surprised of the correlation was real, but the direction of action was reversed…
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Stresses the liver, also if its used frequently for mild inconveniences you should maybe go to the doctor, as frequent headaches or stuff like that can hint to more severe stuff.
What makes you think people who take a painkiller for chronic pain generally don't report it to their doctor?
2. They may be so used to pain they don't think to mention it.
3. A lot of people lie to their doctors for one reason or another.
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Yeah my wife is also pregnant and sometimes it is really tough on her but she doesn't use any medication other than baby aspirin for blood pressure. The alternative is exercise, anti-inflammatory foods, and also realizing that it isn't just your body anymore and you can't hurt somebody else's chances for a very small amount of pain relief.
> Yeah my wife is also pregnant and sometimes it is really tough on her but she doesn't use any medication other than baby aspirin for blood pressure. The alternative is exercise, anti-inflammatory foods, and also realizing that it isn't just your body anymore and you can't hurt somebody else's chances for a very small amount of pain relief. It very much is still your wife's body - what other sentient entity is avail…
There really are risks. It's just not worth it during pregnancy. The pain killing effects of tylenol aren't worth the potential risks during pregnancy. https://www.mountsinai.org/about/newsroom/2025/mount-sinai-s...
There are also real risks to ignoring pain and the destructive effects it has to quality of life and mental well being, all of which can have effects on the mother's and the fetus's health. What is a pregnant person with debilitating pain such as a migraine supposed to do?
There is research correlating autism and mothers taking certain medications (painkillers, antidepressants). Since autism is hereditary, there is a significant chance that these mothers are autistic too. Autistic people have a vastly high risk of depression, and often have unusual pain thresholds, requiring more painkillers. I would not be surprised of the correlation was real, but the direction of action was reversed…
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The fact that we haven't identified candidate genes for autism and a bunch of other mental health issues doesn't mean these aren't hereditary or have hereditary triggers that make outbreaks easier.
> if anything it is epigenetic caused by environmental pollutants and hormone exposure
Doubtful. The difference to older times is, we now properly diagnose mental health issues instead of just labeling affected people as "loons", locking them away in institutions or, like it happened with witch-burnings and in the NS Aktion T4, outright murder them.
It is the safest painkiller currently available. Ibuprofen can cause gut bleeding and renal issues if overdosed on. We all know about opiates. Some facts - typical adult dose is 1g. Max suggested cap on the drug label is 3g per day (about 6 pills at usual 500mg dose). You need to take 10g (20 pills) to be at real risk of hepatotoxicity. So 10 times the typical dose is when you have overdose effects. (basically 20 pil…
> We all know about opiates No, I do not think we do, because it causes none of the side-effects associated with NSAIDs, and it is even safer than acetaminophen, i.e. there is no risk of hepatotoxicity whatsoever. The only side-effect is euphoria. Please do not mention respiratory depression here, that is a non-issue, it matters as so much as liver failure matters with acetaminophen overdoses. Opiates are safer than…
That second part "people misusing/abusing them" is a lot bigger than you're letting on. People can get hooked on opiates easily - a quick trip to Wikipedia turns up: "Long-term opioid use occurs in about 4% of people following their use for trauma or surgery-related pain" [1]. That's a pretty big knock-on effect! If you're prescribed opiates you're rolling the dice, and if you have the right mix of brain chemistry and genetics, you might be screwed.
It is the safest painkiller currently available. Ibuprofen can cause gut bleeding and renal issues if overdosed on. We all know about opiates. Some facts - typical adult dose is 1g. Max suggested cap on the drug label is 3g per day (about 6 pills at usual 500mg dose). You need to take 10g (20 pills) to be at real risk of hepatotoxicity. So 10 times the typical dose is when you have overdose effects. (basically 20 pil…
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Research to develop more effective countermeasures should continue of course, precisely because current vaccines aren’t a full solution. I keep hoping to hear good news about those inhaled vaccines that’ve been in development.
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They do cause constipation
The silent killer