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Ozempic linked to lower Alzheimer's risk in people with Type 2 diabetes

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Re: Ozempic linked to lower Alzheimer's risk in people with Type 2 diabetes

#191

Post by cthalupa »

cynicalpeace wrote: post #189
cthalupa wrote: post #182

Earlier quoted context omitted.

Where? In Japan, obesity among men has increased by 1.5x over the past several decades. It remains quite low, but the rate is still increasing year over year (slower with women). Vietnam, a country with one of the lowest obesity rates in the world is seeing an increase - the overweight and obesity rate has basically tripled since the early 2000s.

Huntington, West Virginia: https://www.advisory.com/daily-briefing/2020/01/27/fattest-c... The solution involved exercise and diet, surprise surprise. It's not magic or some law of nature that people will only get more fat and unhealthy. If we think that way, then it will surely happen though.

Alright - so whole community intervention, including literal celebrity chefs appearing and building out menus, can improve the situation.

Yes, if we remove all of the modern, processed, high calorie, energy dense, sugar heavy foods out of a place we can improve the obesity rate.

I hope you understand why individuals are going to take things into their own hands vs. waiting for massive societal change. I thought you were referring to whole cultures or countries making significant change here, not small communities.

Re: Ozempic linked to lower Alzheimer's risk in people with Type 2 diabetes

#192

Post by AStonesThrow »

Someone1234 wrote: post #20
AStonesThrow wrote: post #10

Earlier quoted context omitted.

My PCP agrees that the great results I'm getting on Fen-Phen mean I won't need to switch!

GLP-1 have already been on the mass market longer than Fen-Phen (7-years for Fen-Phen Vs. 15+ years, even just Semaglutide has been available longer than Fen-Phen now, and Semaglutide is a third-gen GLP-1). Honestly, this retort can be made about any/all new drugs entering the market. If you had a legitimate retort/critique I'm sure you would have presented it, but this is all we get. This is what happens when you st…

I mean it's literally as if people don't understand how drugs work, or what drugs actually do to human bodies.

It is as if those who do not remember the past are repeating it, already.

So many shills are singing the praises of this wonder drug.

  In India we're all the rave
  Discovered that it's great as aftershave, oh-ho
  Dropped in the sea just off Japan
  Swapped twenty bottles for an aqua-walkman, oh
  Immunity from ridicule
  Improves your brains if you're a fool, oh-ho
  And I read in the Middle East
  Traded some for a hostage release
  Now if you're bald it'll give you hair
  If you've got straight trousers it'll give you flares
  Feeling up you'll get depressed
  Out of style here's a brand new dress, oh
  It was really vile weather
  When we got tarred and feathered
  You could hear the six-guns sound
  As they chased us out of town

Re: Ozempic linked to lower Alzheimer's risk in people with Type 2 diabetes

#193

Post by thefz »

cthalupa wrote: post #178
thefz wrote: post #172

Earlier quoted context omitted.

I don't care obesity is rising here and there, the fact that it is culturally induced remains, as it remains that a change lifestyle is the largest defense against obesity. Enjoy the magic pill for the rest of your life.

I'm fairly confident in my ability to get back in the same routine I had in my 20s and take myself off of it, but if staying on it is what it takes for me to remain fit and eating well, then sure. I don't mind giving myself an injection twice a week in exchange for good health. If not needing it makes you feel superior, I'm glad you've found a source of self validation.

Imagine your reaction if smokers were to make the same point and voila, this is how ridiculous it sounds.

Re: Ozempic linked to lower Alzheimer's risk in people with Type 2 diabetes

#194

Post by thefz »

cthalupa wrote: post #191
cynicalpeace wrote: post #189

Earlier quoted context omitted.

Huntington, West Virginia: https://www.advisory.com/daily-briefing/2020/01/27/fattest-c... The solution involved exercise and diet, surprise surprise. It's not magic or some law of nature that people will only get more fat and unhealthy. If we think that way, then it will surely happen though.

Alright - so whole community intervention, including literal celebrity chefs appearing and building out menus, can improve the situation. Yes, if we remove all of the modern, processed, high calorie, energy dense, sugar heavy foods out of a place we can improve the obesity rate. I hope you understand why individuals are going to take things into their own hands vs. waiting for massive societal change. I thought you w…

So you are going to take the drug and keep on eating the same modern, processed, high calorie, energy dense, sugar heavy foods?

Re: Ozempic linked to lower Alzheimer's risk in people with Type 2 diabetes

#195

Post by cynicalpeace »

cthalupa wrote: post #191
cynicalpeace wrote: post #189

Earlier quoted context omitted.

Huntington, West Virginia: https://www.advisory.com/daily-briefing/2020/01/27/fattest-c... The solution involved exercise and diet, surprise surprise. It's not magic or some law of nature that people will only get more fat and unhealthy. If we think that way, then it will surely happen though.

Alright - so whole community intervention, including literal celebrity chefs appearing and building out menus, can improve the situation. Yes, if we remove all of the modern, processed, high calorie, energy dense, sugar heavy foods out of a place we can improve the obesity rate. I hope you understand why individuals are going to take things into their own hands vs. waiting for massive societal change. I thought you w…

My entire point is that individuals should take things into their own hands. By exercising and eating whole foods, not depending on the pharmaceutical system for a panacea that may or may not have long term side effects.

And if enough people do it, we have a healthy culture again.

Re: Ozempic linked to lower Alzheimer's risk in people with Type 2 diabetes

#196

Post by consteval »

cynicalpeace wrote: post #177
consteval wrote: post #156

Earlier quoted context omitted.

> good diet, exercise, sleep and stress management The problem is these are individual solutions. We have a societal-wide problem. These solutions are therefore useless. You can't solve societal problems with individual solutions. For example, I can't say "people shouldn't steal because it's immoral". It's true, and for me or you that might be enough to keep us from stealing. This is an individual solution. The socie…

Culture definitely changes, or else there would be no different cultures. I like bottom-up way to approach it, rather than only top-down via policy. Be healthy yourself and hopefully that bleeds out to your family and friends. If enough people do it, you have a different culture. Certainly possible given all the cultures that do prioritize these things.

> If enough people do it, you have a different culture

This just straight up does not work. I will be blunt - you are not suggesting a solution, you're suggesting a delusion.

This "do nothing and hope it works" approach is not novel. It has been our one singular approach to the obesity epidemic. Has it been working? We have many decades of evidence now. No, it hasn't.

I could maybe see your perspective better if what you're suggesting is not already tried and tested. When you do something for decades at a time and the problem doesn't improve, but in fact gets worse, you have to face the reality that what you're doing just doesn't work.

> Certainly possible given all the cultures that do prioritize these things

They really don't. They just have less access to food.

Some, like Japan, get around obesity by instead having some of the highest tobacco use in the world in combination with a stressed-out population.

As fun as it sounds to reintroduce smoking culture to offset obesity, I think it might make more sense to give people access to safe drugs that help regulate their propensity for overconsumption.

Re: Ozempic linked to lower Alzheimer's risk in people with Type 2 diabetes

#197

Post by amenhotep »

cthalupa wrote: post #106
sandworm101 wrote: post #42

Earlier quoted context omitted.

>> being obese is basically the worst possible thing you can do to yourself Lol. I can think of dozens of worse things. Drinking. Cocaine addiction. Meth. Winding up in prison for some reason. Riding a motorcycle without a proper helmet. Getting into a plane flown by Harrison Ford. Even simple unprotected sex can lead to massive medical problems. Ever looked up the average life expectancy of professional athletes, es…

> Drinking Being obese is probably worse for you. NAFLD has long eclipsed alcohol related liver issues. > Even simple unprotected sex can lead to massive medical problems Even treated HIV is probably less of a risk to your long term health than obesity, but I'm not a doctor. > Cocaine addiction. Meth OK, yes, there are illegal drugs that are going to be worse for you than being fat. I'll rephrase: Being obese is basi…

I like how the implicit sorting at the end here suggests Harrison Ford is ferrying around more people than there are professional athletes. Busy fella!

Re: Ozempic linked to lower Alzheimer's risk in people with Type 2 diabetes

#198

Post by cthalupa »

thefz wrote: post #194
cthalupa wrote: post #191

Earlier quoted context omitted.

Alright - so whole community intervention, including literal celebrity chefs appearing and building out menus, can improve the situation. Yes, if we remove all of the modern, processed, high calorie, energy dense, sugar heavy foods out of a place we can improve the obesity rate. I hope you understand why individuals are going to take things into their own hands vs. waiting for massive societal change. I thought you w…

So you are going to take the drug and keep on eating the same modern, processed, high calorie, energy dense, sugar heavy foods?

No. Where did I ever say that? I take the drug and it makes it significantly easier for me to eat healthy foods and in healthy quantities.

I'm someone who has spent many years of their life fit. I'm also someone who has spent many years of their life fat. I can tell you that when I was fit, I did not suffer from the sort of constant hunger I did before I was fat. It didn't take any sort of willpower or discipline on my part - I just wasn't hungry nearly as often, healthy food was satiating, and things were easy. Lifting weights multiple days a week took a bit of discipline, but it wasn't the reason I was eating healthy - I was doing that before I ever got particularly into exercise.

But I got busy with other aspects of my life and it became easier and easier to just grab some fast food, or order uber eats during the pandemic. But this was just laziness - I didn't have constant hunger or cravings. But before I knew it, I had gained significant weight, and then I did have constant hunger and cravings, and it became a tremendously difficult task for me. Losing weight by sticking to healthy food in healthy quantities required significant willpower, and shoving that hunger down had impact on my mood, ability to concentrate, etc. I struggled to make it past 6 months before some other event in my life would require me put my focus towards it, and I wouldn't have the capacity to deal with both things, so I'd go back to eating poorly.

Tirzepatide puts my relationship with food and hunger back to where it was before I had gotten fat in the first place.

Re: Ozempic linked to lower Alzheimer's risk in people with Type 2 diabetes

#199

Post by cthalupa »

cynicalpeace wrote: post #195
cthalupa wrote: post #191

Earlier quoted context omitted.

Alright - so whole community intervention, including literal celebrity chefs appearing and building out menus, can improve the situation. Yes, if we remove all of the modern, processed, high calorie, energy dense, sugar heavy foods out of a place we can improve the obesity rate. I hope you understand why individuals are going to take things into their own hands vs. waiting for massive societal change. I thought you w…

My entire point is that individuals should take things into their own hands. By exercising and eating whole foods, not depending on the pharmaceutical system for a panacea that may or may not have long term side effects. And if enough people do it, we have a healthy culture again.

If it was that easy, then 'eating better and exercising regularly' wouldn't be the most prescribed and least successful treatment for obesity.

There's countless comments in here from many people explaining why this is the case. If you don't get it by now, I doubt you ever will.

Re: Ozempic linked to lower Alzheimer's risk in people with Type 2 diabetes

#200

Post by cthalupa »

thefz wrote: post #193
cthalupa wrote: post #178

Earlier quoted context omitted.

I'm fairly confident in my ability to get back in the same routine I had in my 20s and take myself off of it, but if staying on it is what it takes for me to remain fit and eating well, then sure. I don't mind giving myself an injection twice a week in exchange for good health. If not needing it makes you feel superior, I'm glad you've found a source of self validation.

Imagine your reaction if smokers were to make the same point and voila, this is how ridiculous it sounds.

I don't begrudge smokers any of the tools they have their disposal for cessation. So yes, they're certainly welcome to make the same point. If using nicotine patches or gum indefinitely is what it takes someone to stop smoking cigarettes, then sure, go for it. It's a hell of a lot less harmful than continuing to smoke two packs of cigarettes a day.

It's quite obvious that you think anyone who is incapable of just willpowering through things is lesser for it. And that's fine - you're allowed to hold whatever opinion you want. Thankfully, neither of us are forced to interact with each other in any real manner.

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