Brain waves appear to wash out waste during sleep in mice

Post by karencarits » Sat, Mar 16, 2024, 7:40 PM UTC

magicalhippo wrote: post #155

robg wrote: post #87

If you have any doubts about sleep quantity and quality, worth reading about the glymphatic nervous system, which is so newly discovered likely you didn’t learn about it in school. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636982/ In short it explains, mechanistically, why poor sleep affects daily cognition, mental health, and age-related declines. Robust scientific theories explain more of the evidence. The glym…

It makes me sad as my SO struggles a lot with sleep. It's been years since she's had a good nights sleep. Sadly her issues are mostly psychologically rooted due to past trauma, while all the treatments seem to be geared towards "simple" physical issues. She's tried contacting various sleep clinics here and they've all said they can't help. She struggles a lot with falling asleep, she's exceptionally sensitive to soun…

Post by skinner927 » Sat, Mar 16, 2024, 7:40 PM UTC

FooBarWidget wrote: post #172

moffkalast wrote: post #124

Earlier quoted context omitted.

I wonder if eventually once this is more thoroughly researched there could be a way to induce constant cleaning instead of having to do it while unconscious at night? Or at least reduce the hours required. If we could solve this we could just stay awake perpetually and instantly gain a 30% longer lifespan as it were.

Philips has a headband product called DeepSleep. They claim it increases your deep sleep by playing some sort of sound during your sleep that induces more deep sleep. For some odd reason, despite being a Dutch company, the product was only sold in the US. I spent a lot of money having it imported to Netherlands. Unfortunately I can't tell whether it works. I rely on headphones and earplugs to block out sounds during…

Post by samstave » Sat, Mar 16, 2024, 7:48 PM UTC

randcraw wrote: post #178

0xFEE1DEAD wrote: post #88

Earlier quoted context omitted.

Have you seen the video on hn a couple of weeks ago about the scientist using ultrasound to halt the progression of Alzheimer’s and to treat addiction? Most fascinating video I’ve seen in a long time. Edit: If you haven’t seen it yet, I highly recommend checking it out https://youtu.be/7BGtVJ3lBdE

IIRC, the goal of that effort is simply to violate the blood brain barrier, which may have therapeutic value only under very tightly managed circumstances since violating it likely will yield at least as many demerits as merits since the BBB is essential to keep the brain free of blood-borne toxins.

Post by calibas » Sat, Mar 16, 2024, 8:08 PM UTC

feverzsj wrote: post #110

In case you didn't know, sleeping on your right side maximizes the clearance effect, while sleeping on your stomach minimizes it.

Post by scrps » Sat, Mar 16, 2024, 8:15 PM UTC

magicalhippo wrote: post #155

robg wrote: post #87

If you have any doubts about sleep quantity and quality, worth reading about the glymphatic nervous system, which is so newly discovered likely you didn’t learn about it in school. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636982/ In short it explains, mechanistically, why poor sleep affects daily cognition, mental health, and age-related declines. Robust scientific theories explain more of the evidence. The glym…

It makes me sad as my SO struggles a lot with sleep. It's been years since she's had a good nights sleep. Sadly her issues are mostly psychologically rooted due to past trauma, while all the treatments seem to be geared towards "simple" physical issues. She's tried contacting various sleep clinics here and they've all said they can't help. She struggles a lot with falling asleep, she's exceptionally sensitive to soun…