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MDMA and psilocybin are approved as medicines in Australia

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Re: MDMA and psilocybin are approved as medicines in Australia

#191
post #122

Earlier quoted context omitted.

5 grams? Most people would absolutely lose their shit on that. Even an eighth of good mushrooms is enough to obliterate most people. Like complete ego death. How long do these sessions last? What are the logistics? I’m very curious.

An eighth won’t give you ego death. 5 grams is about where you start getting kaleidoscopic visuals and good hallucinations In all, the whole trip usually lasts a solid 4 hours. You’re going to be ready to pass out at the end

> An eighth won’t give you ego death. 5 grams is about where you start getting kaleidoscopic visuals and good hallucinations

This is completely dependent on the strain[1] and potency of that batch. It also will depend on the person. To make any definitive statements on what people will experience on x grams is not an informed opinion.

[1] https://leafly-cms-production.imgix.net/wp-content/uploads/2...

Re: MDMA and psilocybin are approved as medicines in Australia

#192
post #63

Earlier quoted context omitted.

recreational doses are not necessarily therapeutic doses if you are taking a psychedelic as part of some therapy regime it is not a tripping balls level dose

Everything I've learned about therapeutic psilocybin treatment is that the doses involved are actually quite a bit higher than I've ever done on a trip at home. For example for psychedelic therapy with psilocybin, you would see a therapist a few times with no psilocybin, then you would have a session where you take something like the equivalent of 1 gram of dried mushrooms, and go through that session with the therap…

> Everything I've learned about therapeutic psilocybin treatment is that the doses involved are actually quite a bit higher than I've ever done on a trip at home

Where are you getting this info? All the good data I've seen is definitely not 5 grams dried. 20-25mg seems to be the sweet spot[1][2][3][4] which is around 2 grams[5].

[1] https://www.nejm.org/doi/full/10.1056/NEJMoa2206443

[2] https://www.thelancet.com/journals/eclinm/article/PIIS2589-5...

[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751063/

[4] https://newatlas.com/johns-hopkins-psilocybin-study-finds-op...

[5] https://www.leafly.com/learn/psychedelics/how-to-dose-mushro...

Re: MDMA and psilocybin are approved as medicines in Australia

#193
post #52

Earlier quoted context omitted.

I bought it as a powder. We snorted a couple mgs. I tested it with one of the reagents and it checked out. I think I'm sensitive to vasocontriction. I'm aways freezing on psychedelics, this one was particularly bad. Shallow breaths, cold, tight chest. If I wasn't on drugs I would have gone to the hospital. Sex was intense though, and light visuals towards the end with trippy thoughts that just shut off at pretty much…

You feel freezing even in MDMA? That seems unlikely.

no, thats the not a psychedelic either

Re: MDMA and psilocybin are approved as medicines in Australia

#194

Earlier quoted context omitted.

Hasn’t been my personal, or my friends experience. Got some source ?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1071023/ > Although initially it proved difficult to find any cognitive sequelae that correlated with these changes,11 recent animal studies have shown subtle, but lasting, deficits in cognitive behaviorsthat do correlate with the levels of damage to 5-HT systems in the hippocampus. https://www.frontiersin.org/articles/10.3389/fnins.2015.0044... > In this study, we found a…

In animals ?

Re: MDMA and psilocybin are approved as medicines in Australia

#195

Earlier quoted context omitted.

Everything I've learned about therapeutic psilocybin treatment is that the doses involved are actually quite a bit higher than I've ever done on a trip at home. For example for psychedelic therapy with psilocybin, you would see a therapist a few times with no psilocybin, then you would have a session where you take something like the equivalent of 1 gram of dried mushrooms, and go through that session with the therap…

Jesus. five grams would scare me. does it just not work to use an eighth?

So in a clinical setting they actually give 20-30mg of psilocybin directly. This works out to approximately 3-5g of dried cubensis depending on their potency.

Re: MDMA and psilocybin are approved as medicines in Australia

#196
post #192

Earlier quoted context omitted.

Everything I've learned about therapeutic psilocybin treatment is that the doses involved are actually quite a bit higher than I've ever done on a trip at home. For example for psychedelic therapy with psilocybin, you would see a therapist a few times with no psilocybin, then you would have a session where you take something like the equivalent of 1 gram of dried mushrooms, and go through that session with the therap…

> Everything I've learned about therapeutic psilocybin treatment is that the doses involved are actually quite a bit higher than I've ever done on a trip at home Where are you getting this info? All the good data I've seen is definitely not 5 grams dried. 20-25mg seems to be the sweet spot[1][2][3][4] which is around 2 grams[5]. [1] https://www.nejm.org/doi/full/10.1056/NEJMoa2206443 [2] https://www.thelancet.com/jou…

Fuzzy memory from what I learned a few years ago. I guess i was really responding to the person who said “you’re not tripping balls in a therapeutic setting” - personally even 2 grams is “tripping balls” by my standards, but like I said 2 grams is the most I’ve ever done.

Re: MDMA and psilocybin are approved as medicines in Australia

#197

Earlier quoted context omitted.

We hope to be able to try it some day, since we have DID and heard that psychedelics can actually help a lot. It's a shame that we'll probably have to wait years, though... -Emily

Why you sign your comments? Just genuinely curious.

I started signing my comments after I began posting to DID subreddits about a month ago. It's because I write differently than Logan does and also don't necessarily remember everything he does anymore (and vice versa), so it can be useful for people to know who they're talking to.

It's also useful for us to keep track of who wrote each one of our comments, personally, so if Logan sees something he doesn't remember for example, he'll know who's responsible.

-Emily

Re: MDMA and psilocybin are approved as medicines in Australia

#198

Earlier quoted context omitted.

Why you sign your comments? Just genuinely curious.

Because they claim to have DID, and thus are saying that at that particular time, they are "fronting" with a persona they call Emily. FWIW, a large amount of the psychiatric establishment believes DID to not be real, per se. Instead they think it can be caused by an especially suggestible patient responding to a therapist or other psychiatric professional's coaching. Essentially playing a role in the therapy (for gen…

We're not just personas, but other than that, that is a fairly accurate description. I am indeed "fronting" right now. Logan (the holder of this account, and the username "LoganDark") is currently dormant for mental health reasons, so he's basically unconscious.

The claim is indeed just a claim at the moment, sadly, because we're not professionally diagnosed, though we are working towards a diagnosis. (Right now we're waiting for a call back from what is presumably the world's most overbooked mental health center. Only possible explanation for them taking this long.)

> FWIW, a large amount of the psychiatric establishment believes DID to not be real, per se. Instead they think it can be caused by an especially suggestible patient responding to a therapist or other psychiatric professional's coaching. Essentially playing a role in the therapy (for genuine underlying problems!) that they believe they are expected to play.

Believing DID isn't "real" (as in, is not caused by actual brain structure changes) is different than believing that it can be achieved through other means.

There are two main definitions of "DID", and it's important not to get them mixed up in cases like these: "DID the canonical disorder" (which we may or may not have), a direct consequence of certain types of structural dissociation[0], and "DID the set of symptoms" (which we definitely do have) as established in the DSM-5[1], which can apply regardless of root cause.

Some believe that "DID the canonical disorder" does not exist, and that it is akin to subconscious pretending (as you describe). Some believe that "DID the set of symptoms" can be achieved through different means than through structural dissociation in childhood. These beliefs are largely independent, although it would be weird to believe the first but not the second.

(I should add that believing you can willingly create certain specific symptoms of DID (such as plurality) is different from believing that you can create DID itself willingly. The development of DID itself must necessarily be non-willing due to its diagnosis as a disorder, but certain symptoms (such as plurality) can be developed through practice[2] without having any dissociative disorder.)

---

A lot of GPs don't even know DID exists. I once brought it up to our doctor and he had no idea what I was talking about. (I later found out that he had slipped "dissociative disorder" into our medical record. Sneaky~)

The "realness" of "DID the canonical disorder" is incredibly debatable. There is the theory of structural dissociation[0] but that only explains how it forms in the first place and not how it develops or functions over time.

Before learning of "plural" terminology[3] in the first place, for around 4 years, we simply knew ourselves as "multi-personality". We didn't appropriate anything because we had no access to that information.

But I do know for a fact that, since finding out about "plurality" and becoming much more public about it (including socializing in "plural" spaces), we have subconsciously appropriated many mechanisms as they were described to us, mainly when they were a better method of serving some function that we had to perform anyway, but also sometimes for other reasons. We've never been in therapy or even professionally diagnosed, so the development of plurality itself couldn't have been informed by medical professionals.

It was developed and strengthened through roleplay, though, as far as we know. The exact details of this are probably too anecdotal to recount in full detail, but in summary: we were allowed to express individually on a website with individual character profiles, and this is likely how we developed into our own people, or at least what prompted us to develop in this way. We didn't happen completely spontaneously, but we also didn't happen because we were shown or guided to act this way. Our brain had some sort of propensity to plurality already, before we ever knew anything about it.

[0]: https://did-research.org/origin/structural_dissociation/

[1]: No definitive source here, but try googling: DSM-5 filetype:pdf

[2]: https://tulpa.io/what-is-a-tulpa

[3]: https://morethanone.info

-Emily

Re: MDMA and psilocybin are approved as medicines in Australia

#199
post #141
post #137

I see quite a number of comments making some very wildly inaccurate statements about the pharmacological safety of MDMA. There have been a number of studies conducted about the health impact of MDMA. In monkeys, it has been shown to leave behind long-term brain damage, serotonin receptor damage for at least 7 years, etc. Personally, back at University I had some acquaintances who got quite addicted to them and appear…

Do you have sources for that comparison of Opioides with MDMA? I also couldn't find much studies on MDMA itself, as most such studies refer to some sort of pills, which are usually mixed with other drugs (e.g. Speed).

The Wikipedia article has a tonne of links to studies that link amphetamines to addiction, which is also a primary trait of opiates. Opiates also have negative side-effects with abuse, just like amphetamines.

They have many similarities.

> and extended use can also lead to addiction, memory problems, paranoia and difficulty sleeping

Etc.

Re: MDMA and psilocybin are approved as medicines in Australia

#200
post #63

Earlier quoted context omitted.

recreational doses are not necessarily therapeutic doses if you are taking a psychedelic as part of some therapy regime it is not a tripping balls level dose

A therapeutic MDMA dose is basically equivalent to a recreational dose from the literature I've read. Not sure about psilocybin. Ketamine dosage definitely leads to tripping balls.

Not at all actually. I underwent 11 weeks of ketamine therapy. No hallucinations whatsoever, and I checked with others because I thought I was missing out! I felt physically drunk, but mentally absolutely clear. You may be thinking of a higher dose taken recreationally.
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