191–200 of 228 posts
I'm a month into taking rapa and already I feel like it's having a noticeable effect. I'm curious what others on this threads dosage looks like. If you prefer to keep it private, you can email me directly (my email is on my profile). I'm currently taking 2mg once a week on my rest day; I started with 1mg and after 1 month added another MG. I'll continue each month until I reach 8MG once a week, which is the dosage th…
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Depending on where you are, everything can cause cancer. This website is known to the State of California to cause cancer.
One of the additives I work with in pottery is labeled with a prop 65 warning. The only ingredient is silicon dioxide, aka sand.
Before you take any drug chronically - particularly something KNOWN to block a gene cascade receptor - be sure there are good studies (sufficiently powered, peer-reviewed, phase-III studies in humans with actual endpoints and significant positive results).
And be sure the "researchers" you're relying are not just PhD's or retired doctors regurgitating dubious studies.
Remember: the essence of a good scam is that it is partly true.
Readers will get more longevity from walking instead of reading these studies. Avoiding toenail fungus will improve your lives more. Those have real data behind them.
genuine question: why would someone want to live longer than the average? Edit: I ask because I personally don't see a reason to stay alive while people I love are dying, I don't see a reason to stay alive in an already fucked up planet, while we empty all the resources, etc. But you guys are so smart, intelligent and clever, why even bother.
I'd like to be healthy enough to help them when they are dying.
This part sounds familiar: "One step closer to applications"
I know and agree with this sentiment. However, you can take Rapamycin now. It is an existing drug.
No: your doctor can prescribe it for you if it's indicated, or when there's good evidence that you need what it can do more than the side effects you'll suffer.
It's just like a gun: useful in some situations. But unlike guns, it's not you who decides.
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Your concern is correct. Suppressing the immune system is a 2-edged sword - a little suppression in the right setting, is extremely beneficial, but go overboard and it is harmful. That's why in a perfect world, we would have large human trials with different dosages and iterate until we can get the maximum benefit and the least harm. The problem is, no one wants to do those trials because rapamycin is cheap and gener…
> The problem is, no one wants to do those trials because rapamycin is cheap and generic. Why would Pharma spend money on something that they can't patent? Same issue with psychedelics. However, they are so useful that people in the medical/therapeutic/academic fields are doing tons of research anyway. Apparently big pharma is also trying to create their own psychedelics (there was an article about it on the front pa…
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Anything David Sinclair has endorsed should be considered with at least double the normal skeptical scrutiny.
Lol, why do say that? I had the same impression of him. It appears that people fall for his niceness is my theory about him. And no doubt he is a nice guy. It's just that his explanations lacked the rigor I generally look for.