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Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

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Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#191

Post by mikeyouse »

swader999 wrote: post #188
mikeyouse wrote: post #183

Earlier quoted context omitted.

Sometimes the timing is just great -- how about the fact that the protocol was designed by several grifters selling fraudulent "long Covid" tests and charging people thousands of dollars for tele-health visits where they then lie about lab tests and prescribe drugs that don't remotely work. Just published now: https://www.motherjones.com/politics/2022/01/desperate-patie... These people should be in prison.

I didn't suggest anyone use IncellDX or covid long haulers.com. Just because Bruce Patterson had his name associated with the flccc doesn't prove anything about it's viability. Keep trying.

If the fact that fraudulent grifters developed the treatment protocol you're advocating for, I'm not sure where to go from there. (Not just Patterson, but Yogendra too -- it's not just "his name associated" with flccc -- he and yogendera are two of the primary authors of the protocol!)

And if I understand your timeline right --- you think a single dose of the vaccine gave you "long covid" symptoms? So you're going to rely on the long-covid treatment path, even though you've never had the virus? Yikes man..

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#192

Post by swayvil »

SketchySeaBeast wrote: post #163
swayvil wrote: post #161

Earlier quoted context omitted.

Well if they have no symptoms then they aren't really diseases, right? And there are a thousand species of varmint that inhabit our body without helping or hurting anyway. So yes, massive unhealth can definitely spell the difference there.

I'm not following. For some people a cold can have basically no symptoms and can even spread asymptomatically, and for most people it's just an irritation, but for the especially vulnerable it can kill. Would you argue that the common cold is also not a disease?

The key word here is "for some". If nobody gets a symptom then it isn't a disease. If only a very few get a symptom then maybe we call it a disease and maybe we call it something else.

A disease requires some minimum proportion of the infected to feel it. Otherwise it's just commensalism or something.

Therefore, as the general health shifts, so does what we call our relationship with that varmint.

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#193

Post by [deleted] »

swader999 wrote: post #188
mikeyouse wrote: post #183

Earlier quoted context omitted.

Sometimes the timing is just great -- how about the fact that the protocol was designed by several grifters selling fraudulent "long Covid" tests and charging people thousands of dollars for tele-health visits where they then lie about lab tests and prescribe drugs that don't remotely work. Just published now: https://www.motherjones.com/politics/2022/01/desperate-patie... These people should be in prison.

I didn't suggest anyone use IncellDX or covid long haulers.com. Just because Bruce Patterson had his name associated with the flccc doesn't prove anything about it's viability. Keep trying.

[deleted]

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#194

Post by surgeryres »

Very interesting study.

I am an expert in the field of clotting mechanics (US NIH funded research / vascular surgery fellow). Not sure why they chose TEG to monitor coagulation status - it does not reflect well changes from any of the drugs used in the study.

It would be interesting to see the results broken down by gender - females respond much differently to aspirin and have less of a survival benefit than males (don’t get me started, many of the initial trials in the 60’s with aspirin were done with mostly males).

Also, in my own research - we have found that aspirin “softens” clots which allows platelets to squeeze pathological clots to smaller sizes, which allows more recannalization of thrombosed vessels and thus less ischemia - would be interesting to see if that same MOA happens here.

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#195

Post by swader999 »

mikeyouse wrote: post #191
swader999 wrote: post #188

Earlier quoted context omitted.

I didn't suggest anyone use IncellDX or covid long haulers.com. Just because Bruce Patterson had his name associated with the flccc doesn't prove anything about it's viability. Keep trying.

If the fact that fraudulent grifters developed the treatment protocol you're advocating for, I'm not sure where to go from there. (Not just Patterson, but Yogendra too -- it's not just "his name associated" with flccc -- he and yogendera are two of the primary authors of the protocol!) And if I understand your timeline right --- you think a single dose of the vaccine gave you "long covid" symptoms? So you're going to…

Yikes man indeed. Hard to describe how desperate I was back then. If you read the protocol, you'd see where they describe how a subset of vaccine injury and long covid essential present and are treated identically.

My story: got all the long covid symptoms, started eight hours after the AZ vaccine. Tested negative twice on pcr. 3.5 months with little improvement. Optometrist noted blood heme in eye, had a clot removed from forehead vein recently. Both of those noted within a week or three of vaccine date. At the 3.5 month date I started that protocol, first with ivermectin. Within five hours I felt better than I had in the past three months and then in five days brain fog, sob, headaches, extreme fatigue, heart issues, high blood pressure all resolved. I quit the daily dose of ivm then and started prednisone for remaining lung inflammation. (Describe this like extreme asthma, any deep inhalation would trigger coughing). That worked. I still have a bit of a dry like congestion that lingers (8 months since vax).

Maybe I caught covid same time frame as vax but the two negative tests seem to not support that. The symptoms certainly presented right after the shot. They very clearly resolved a few hours after the ivermectin. It was like a light switch. My wife noticed improvement in my color even.

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#196

Post by hackerfromthefu »

lmkg wrote: post #100
nradov wrote: post #86

Earlier quoted context omitted.

None of that implies that COVID was the cause. It could just be a coincidence.

> Correlation doesn't imply causation, but it does waggle its eyebrows suggestively and gesture furtively while mouthing 'look over there'. Randall Munroe, https://xkcd.com/552/ (mouseover text)

Imply != Prove

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#197

Post by SketchySeaBeast »

swayvil wrote: post #192
SketchySeaBeast wrote: post #163

Earlier quoted context omitted.

I'm not following. For some people a cold can have basically no symptoms and can even spread asymptomatically, and for most people it's just an irritation, but for the especially vulnerable it can kill. Would you argue that the common cold is also not a disease?

The key word here is "for some". If nobody gets a symptom then it isn't a disease. If only a very few get a symptom then maybe we call it a disease and maybe we call it something else. A disease requires some minimum proportion of the infected to feel it. Otherwise it's just commensalism or something. Therefore, as the general health shifts, so does what we call our relationship with that varmint.

I'm still confused, because I don't know how that connects to your question "Could covid not actually be just a disease?", because it clearly is as it's affecting people. If we assume that the cold is a disease so is COVID, by the same criteria. Is the cold not just a disease? If so, what is just a disease?

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#198

Post by senectus1 »

wantsanagent wrote: post #44

This is a big hammer. Please note this section: "A proton pump inhibitor (PPI) pantoprazole 40 mg/day was also prescribed for gastric protection. Such a regime must only be followed under strict and qualified medical guidance to obviate any dangers, especially haemorrhagic bleeding, and of the therapy as a whole." Induced hemophilia is no joke.

yikes, PPI's. As a GERD sufferer thats come off PPI's after years of use, I wonder if non GERD sufferers will get the "kick back" when they come off the PPI's.

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#199

Post by swayvil »

SketchySeaBeast wrote: post #197
swayvil wrote: post #192

Earlier quoted context omitted.

The key word here is "for some". If nobody gets a symptom then it isn't a disease. If only a very few get a symptom then maybe we call it a disease and maybe we call it something else. A disease requires some minimum proportion of the infected to feel it. Otherwise it's just commensalism or something. Therefore, as the general health shifts, so does what we call our relationship with that varmint.

I'm still confused, because I don't know how that connects to your question "Could covid not actually be just a disease?", because it clearly is as it's affecting people. If we assume that the cold is a disease so is COVID, by the same criteria. Is the cold not just a disease? If so, what is just a disease?

It's a pretty simple idea. I'm having doubts about this "confusion".

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#200

Post by LinuxBender »

sithadmin wrote: post #99
LinuxBender wrote: post #40

Earlier quoted context omitted.

Absolutely not anti-coagulants. They work in conjunction with them to break up clots and absolutely have many different mechanisms. I use six of those mechanisms for controlling blood pressure. The article topic covers fibrin amyloid microclots which is precisely what many surgeons have used these enzymes for in addition to removing scar tissue from the vasculature. On a side note this is a very divided and heated to…

You're specifically using compounds like nattokinase to control blood pressure? Would be interested in hearing what your approach here is, or any literature you could share.

You're specifically using compounds like nattokinase to control blood pressure?

Correct.

Here [1] is one of the studies though there are quite a few on nih.gov that vary in results and P-value. In full disclosure I use much higher FU's than what is used in their test and have been using it for a long time building up to those levels so my risks are lower. I use this in combination with vascular de-calcification methods and other molecules that break down plaques.

I don't have any of them handy but you can also find some videos that talk about the different mechanisms that Natto interact with that affect BP. It is surprisingly not what one might expect. While it does bind to ACE2 that has a very insignificant role in BP. The biggest effect comes from how it changes a feedback mechanism in a peptide chain. I was taken aback when I learned how many roles peptides play in mammals well beyond tissue repair.

On a fun side note Natto also has an effect on von Willebrand factor which is also plays a significant role in covid.

I should of course add that I am not a doctor and this is not medical advise. Enzymes can break down scar tissue, plaques and more. These come with some risk of bleeding and stroke - one must study the risks and discuss with their doctors that will likely give them blank stares until they say "orally bioavailable tissue plasminogen activator" which is not entirely correct but it will help them understand the intent and might tickle their curiosity.

[1] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066864/

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