191–200 of 289 posts
> Malaria strains found on the Cambodia–Thailand border are resistant to combination therapies that include artemisinins, and may, therefore, be untreatable.
Having a vaccine as effective as this new one would save many lives.
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I grew up in Africa. We weren't as scared of Ebola, as we were, of good old Malaria. It's also the gift that keeps on giving. Once you get it, it does a reunion tour, every now and then, for the rest of your life. At the dinner table, we (expats) used to have a bowl of quinine tablets, set out like a condiment. I really hope this works out, because, thanks to climate change, the lower 48 may get a chance to find some…
> Once you get it, it does a reunion tour, every now and then, for the rest of your life. Maybe only certain strains of malaria do that? I had malaria many years ago. It was a very unpleasant experience, but I recovered in a couple of weeks with no lingering effects. Growing up in India, malaria was common. But I don't recall anyone living in terror of it. Mosquito nets, mosquito repellent incense, repellent cream, t…
The way it was explained to me, is that it's a parasitic disease, and the parasites would embed eggs in tissues, with the possibility of the eggs (or whatever they are -spores?) being re-released in the future.
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> Malaria used to be common in the US until the 1950s or so. I had no idea of that, as I suspect many given the time past if you wasn't around then. Did a little digging and nicely covered here: https://www.cdc.gov/malaria/about/history/index.html Which makes me wonder - what the cost of malaria drugs are and how much would it cost to eradicate it. Equally have the true environmental and ecological aspects of eradica…
Afaik mosquitoes don’t really contribute ecologically. They are just nuisance.
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I've used throwaway accounts here for a decade, since I post infrequently and don't care about karma, and it's never been a problem. Further, my comment wasn't flamebait (or anything otherwise objectionable) and shouldn't have been flagged. While I have you, dang: the flagging on this site is out of control. Why do you allow users to so easily hide from others comments they dislike? The downvoting, I don't care about…
Although I turned off the flags on your comment, I don't agree that it wasn't flamebait. It was off-topic, generic, and provocative. It was even name-calling too ("ghastly"). That's a flamebait cocktail. Creating accounts for every few comments you post is a problem for the reason I just explained. Doing it for a decade doesn't make it ok. It makes it worse! In a way, this is a freeloader problem. The richness of the…
That's a perfectly apt description of someone who desires the death of others, especially the death (by extension) of their own parents and grandparents in the name of some vague notion of "progress." And many of these same people then laud a vaccine that will increase the life expectancy and reduce the suffering of millions of people, oblivious to the contradiction.
>In a way, this is a freeloader problem. The richness of the community here comes from people interacting and relating with each other over time. On HN people are welcome to do that anonymously (pseudonymously, for those who speak pedantic), but still need some identity for others to relate to. If you don't contribute that, you're freeloading in the sense that you're benefiting from what other people are giving, without giving anything comparable of yourself.
Dang, as far as I'm concerned, I'm the one who's contributed and asked for nothing in return. I never asked for points (karma), or the ability to censor (flag) others' posts I dislike, or the ability to de-emphasize those posts (downvote). Meanwhile, I routinely see "uberusers" here get leeway, not just from you, but from the flag- and downvote-happy users, that anonymous users like me do not get.
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Although I turned off the flags on your comment, I don't agree that it wasn't flamebait. It was off-topic, generic, and provocative. It was even name-calling too ("ghastly"). That's a flamebait cocktail. Creating accounts for every few comments you post is a problem for the reason I just explained. Doing it for a decade doesn't make it ok. It makes it worse! In a way, this is a freeloader problem. The richness of the…
>ghastly That's a perfectly apt description of someone who desires the death of others, especially the death (by extension) of their own parents and grandparents in the name of some vague notion of "progress." And many of these same people then laud a vaccine that will increase the life expectancy and reduce the suffering of millions of people, oblivious to the contradiction. >In a way, this is a freeloader problem.…
What blows me away is in a study group of 734 infants, which benefited from maternal antibodies against malaria, 717 were infected by malaria in the first year of their life. That's nearly 100%, in the first year since birth. That's devastating. The vaccine is showing 77% efficacy in trials in Burkina Faso. That's an ongoing pandemic that makes covid-19 look like a case of the sniffles. Malaria deaths peaked around 9…
malaria vector is mosquitoes, which are particularly devastating in tropical areas with rainy seasons that end up with numerous stillwater deposits. Stillwater deposits (i.e. no fish) are the perfect breeding grounds for mosquitoes. If you have a very wide area with poor transportation infrastructure, or if you don't have funds to fumigate for mosquitoes...you are toast. The incidence rate should not be surprising fo…
It's interesting how everyone in this thread (rightly) views this as a promising development, yet whenever articles are posted discussing longevity research, you see ghastly comments like this: https://news.ycombinator.com/item?id=26211722 Isn't that hypocritical?
I'm one of the people who agrees with both sentiments. I think decreasing child mortality is great and that humanity needs people to eventually die. Dying in itself is not an issue. Early mortality is an issue. Give everyone the chance to live a full life.
People will eventually die with or without aging. Consider accidents, suicides, homicides, or other non-age related illnesses.
Do you think humanity needs billions of people to eventually develop Alzheimer's or other terminal late-life dementias?
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Not sure why you were downvoted down much but here’s my 2 cents. I first started taking anti-malarial medicine as a child. My entire life I’ve been hearing of resistance to one drug and then another drug, and then another. Also, whenever we took chloroquine or any other drugs on a regular basis, we were well aware that having the medicine in our body would not prevent malaria—-we took it just to help reduce the sever…
Thats a weird argument. "Lets not give the medicine that might help as that might also encourage mutations." --> basically you are saying let's deny it to the many dying today in order to ensure the few (that can afford it) can still use it in the future. A deeply immoral and selfish perspective if spelled out this way. The only solution then is rapid and large-scale intervention. Massive use of the most effective/le…