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Pfizer submits Covid vaccine to FDA for approval, to distribute in December

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Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#191

Post by joaomacp »

tjpnz wrote: post #176

How would one explain to a Facebook addict why they should get the vaccine and that it's not a Bill Gates/NWO conspiracy to sterilise them?

Don't try to convince them forcefully, or else you will strengthen their belief in brainwashing. Explain rationally why YOU believe the vaccine works, and the evidence as to why you are convinced, and accept if they don't change their beliefs.

From experience, sometimes people are very refusing when arguing in person, but over time they think it over and might change their mind.

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#192

Post by prh8 »

qwerty456127 wrote: post #16
DSingularity wrote: post #3

Does this feel rushed to anyone? Why don’t they stagger the release? Why jump from initial trials involving thousands to widespread distribution involving millions?

Despite being extremely pro-vac I'm going to postpone getting vaccinated with this for as long as possible (at least a couple of years hopefully). Even if they would disallow me to travel abroad I would rather stay in my home country. I've heard about a guy who volunteered to try the Russian vaccine - he got extremely sick and almost died from inflammatory cardiomyopathy as the result. So I want to see thousands of p…

So....don't take the Russian vaccine?

Maybe take notice the of 20k in each trial who have received the vaccine?

Or maybe just go get Covid and trust those results?

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#193

Post by White_Wolf »

aviraldg wrote: post #106
White_Wolf wrote: post #90

Earlier quoted context omitted.

2009-2010 GSK H1N1 - settled by the gov of multiple EU countries https://www.cdc.gov/vaccinesafety/concerns/history/narcoleps...

> In 2018, a study team including CDC scientists analyzed and published vaccine safety data on adjuvanted pH1N1 vaccines (arenaprix-AS03, Focetria-MF59, and Pandemrix-AS03) from 10 global study sites. Researchers did not detect any associations between the vaccines and narcolepsy.

tbh I had the vaccine back then and am still fine(or I'm dreaming right now). That doesn't mean I'm for or against this new vaccine. I'll draw my conclusion when I see enough data. At the end of the day it's my choice if I do it or not since if you take the jab you should be safe either way.

That being said: shutting down discourse I'm always against. Dumb or not everyone should be able to have their say as long as they don't preach violence in any way.

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#194

Post by [deleted] »

jdndbfbf wrote: post #169
bluGill wrote: post #154

Earlier quoted context omitted.

I'll take my chances. My sister-in-law is dead. A brother-in-law is still unsure if we can talk across a room without fainting (6 months ago he was running several miles a day). This is just in my tiny circle of close family. Thousands in a much larger sample of had the vaccine with no side effects anywhere near that bad.

n=1 is irrelevant I don't care about one persons experiences.

[deleted]

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#195

Post by lfuller »

xiphias2 wrote: post #89
refurb wrote: post #61

Earlier quoted context omitted.

As someone who has some experience with clinical trials and drug approvals, I'd be quite comfortable taking the vaccine. A clinical trial size of 40,000 (20,000 receiving the vaccine) is way larger than a lot of other drugs that people are comfortable taking. Is there zero risk of serious side effects? Of course not, there never is. But the trial gives enough data to say the risk is worth the benefit. Edit: The FDA h…

It also depends on the known safety profile. With AstraZeneca some people already have to take pain medications after taking the vaccine...I wouldn't be comfortable putting using that vaccine without much wider testing. Fortunately I don't need to though, because soon we'll probably have 2 great vaccines to choose from.

Is that not a common side effect of all vaccines? I can't think of a time when I haven't had to take Advil for a couple days after getting the flu shot due to body aches.

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#196

Post by Mordisquitos »

jdndbfbf wrote: post #169
bluGill wrote: post #154

Earlier quoted context omitted.

I'll take my chances. My sister-in-law is dead. A brother-in-law is still unsure if we can talk across a room without fainting (6 months ago he was running several miles a day). This is just in my tiny circle of close family. Thousands in a much larger sample of had the vaccine with no side effects anywhere near that bad.

n=1 is irrelevant I don't care about one persons experiences.

What about 35% of respondents in n=292 (https://www.cdc.gov/mmwr/volumes/69/wr/mm6930e1.htm?s_cid=mm...)?

"Interviews were conducted 14–21 days after the test date. [...] Among 292 respondents, 94% (274) reported experiencing one or more symptoms at the time of testing; 35% of these symptomatic respondents reported not having returned to their usual state of health by the date of the interview (median = 16 days from testing date), including 26% among those aged 18–34 years, 32% among those aged 35–49 years, and 47% among those aged ≥50 years. Among respondents reporting cough, fatigue, or shortness of breath at the time of testing, 43%, 35%, and 29%, respectively, continued to experience these symptoms at the time of the interview. These findings indicate that COVID-19 can result in prolonged illness even among persons with milder outpatient illness, including young adults."

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#197

Post by coldcode »

paulie_a wrote: post #170
thinkingemote wrote: post #125

Earlier quoted context omitted.

Its likely, that, like the flu jab, those most at risk will get it first. The vast majority of diligent users here will not be beta testers. Depending on how it works that is. It might be more effective to jab those most likely to transmit the disease first. (E.g. medical workers, children before Christmas meeting the family) or it might be better to jab those most at risk first.

I am one of those most at risk people and like hell am I going to get it first. It looks like it will be safe but I can weather a few more months self isolation while it is adopted on a more massive scale.

Me too, give my issues with asthma/age and not having a family to support me if I get ill, I am ready right now. If other people choose to wait 10 years that is their option.

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#199

Post by anonuser123456 »

bluGill wrote: post #134
unnouinceput wrote: post #117

Earlier quoted context omitted.

Why would you be upset for? It's their life, not yours. Once you get vaccinated, ideally, you get immune to the virus. You neither can develop the disease nor spread it. It's the same as saying you don't want to work with people who didn't got vaccinated by any other number of vaccines (let you search wiki for full list as exercise) and I'm pretty sure it already happened.

Because it is only 95% effective. If everyone around me is also vaccinated it is likely that even if my vaccine doesn't work I'm still protected. This is what herd immunity is about. Note that we don't know if vaccinated people can spread covid or not. It seems unlikely, but if it turns out being vaccinated means you become a non-symptomatic super spreader I reserve the right to change my stance based on that informa…

The 95% effective is not a cliff function. The 5% that ‘get it’ have mild symptoms. We won’t know how effective it at preventing serious disease until millions have been inoculated, but it will likely be 99%+ effective with that outcome.

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#200

Post by coldcode »

dragonwriter wrote: post #152
sekai wrote: post #103

Earlier quoted context omitted.

Few key facts: • In the entire history of vaccines, only one has been recalled because the vaccine itself caused long term side effects (a rotavirus vaccine that had rare complications and no deaths for those under 1yr). If you can't find any papers about it, that's why. It's like finding a paper on death by lava lamp explosions. It's happened ( https://www.latimes.com/archives/la-xpm-2004-dec-01-na-brief... .), but…

> These studies were larger than usual to make up for the decreased time Larger studies don't make up for decreased time in either identifying long term effectiveness or identifying delayed effects.

If you want to wait a lifetime to see if there are any issues you have that choice. But vaccines, even mRNA ones, are unlikely to have any long term effects worse than the disease itself.
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