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Prions, Nearly Indestructible and Universally Lethal, Seed the Eyes of Victims

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191–195 of 195 posts

Re: Prions, Nearly Indestructible and Universally Lethal, Seed the Eyes of Victims

#191
post #49

Earlier quoted context omitted.

Just when I thought my home state couldn't embarrass me more by being backwards... Thanks!

I've heard more about my home state's alleged consumption of squirrel brain outside the state than in it. And I have a couple kitschy KY cookbooks with recipes for burgoo, entirely rodent free. Every place will have hillbillies who eat odd game meat, if you search hard enough. KY just seems to be a popular target for this topic.

There’s a recipe in the new Appalachian cookbook by Ronnie Lundy, Victuals.

Re: Prions, Nearly Indestructible and Universally Lethal, Seed the Eyes of Victims

#192
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Re: Prions, Nearly Indestructible and Universally Lethal, Seed the Eyes of Victims

#193
post #83

Earlier quoted context omitted.

If they can replicate imperfectly, they're subject that evolutionary processes.

They don't replicate. Prions can't themselves make more prions like viruses do.

Viruses can't replicate themselves either. Cells replicate viruses. And prions replicate by deforming healthy proteins.

Whether that replication can be incorrect and produce a different kind of prion, I don't know. If it can, evolution will do its work.

Re: Prions, Nearly Indestructible and Universally Lethal, Seed the Eyes of Victims

#194
post #187

Earlier quoted context omitted.

the prevalence of the PNRP gene is much better explained by periods of time when humans were very cannibalistic. This makes more sense behaviorally as well, since humans are very difficult to program with instincts. I would bet dollars to donuts that the average hunter gatherer/early farmer had no such revulsion. Meat is meat.

Well here is the major point: there is only one prion (PRNP), for which all mammals seem to be susceptible to disease. It would be odd if deer and sheep had coevolved the same resistances and susceptibility to PRNP due to human cannibalism

prevalence is not existence.

Re: Prions, Nearly Indestructible and Universally Lethal, Seed the Eyes of Victims

#195
post #194

Earlier quoted context omitted.

Well here is the major point: there is only one prion (PRNP), for which all mammals seem to be susceptible to disease. It would be odd if deer and sheep had coevolved the same resistances and susceptibility to PRNP due to human cannibalism

prevalence is not existence.

Not sure what that means
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