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Ibuprofen alters human testicular physiology

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Re: Ibuprofen alters human testicular physiology

#191

Post by saurik »

randallsquared wrote: post #173
rconti wrote: post #109

Earlier quoted context omitted.

Yup; after seeing my mom be recommended 3-4 pills every 6 hours as needed for knee pain, I sure don't bother with just 2 pills as a 200# male if I "need" ibuprofen. I either take 3, or I take nothing. Fortunately I have no chronic issues, rarely need ibuprofen (in fact I'm paranoid about taking it for muscle aches as I've always felt it must harm muscle development, which seems to be catching traction as a theory), a…

TIL that my pain is weak and mild, even when I think I'm in a lot of pain. I'm well over 200 lbs (still), but 200mg of ibuprofen usually eradicates whatever pain I have. If it's really bad pain, then I take 400mg.

TIL I have only experienced pain a few times in my life, and this apparently doesn't even include when I have had extensive dental work done as I don't let them give me any novocaine and don't mind them drilling into my teeth or cord packing my gums.

I am really hoping that it isn't just that you all are like, five years older than I am, and so I have to expect that I am going to just end up in pain a lot soon :/.

Re: Ibuprofen alters human testicular physiology

#192

Post by pennaMan »

toomanybeersies wrote: post #80
ribosometronome wrote: post #45

Earlier quoted context omitted.

> marijuana Unless that makes you anxious.

In that case, use ketamine? In all seriousness though, there is research being done and evidence to suggest that ketamine can be used for pain management. Most of it seems to be about using it synergistically with opioids, to reduce the amount of opioids required.

sadly ketamine has severe side effects https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678404/

Re: Ibuprofen alters human testicular physiology

#194

Post by 52-6F-62 »

disconnected wrote: post #27
MollyR wrote: post #3

It would be mind boggling if pain killers were connected to dropping male fertility. It might even explain why so many cultures had rites to male adulthood involving extreme pain.

> It might even explain why so many cultures had rites to male adulthood involving extreme pain. Right. And a notable trend among those cultures is that they are all nearly extinct. So much for their fertility. Of course this observation could biased due to my own ignorance. I only remember, like, 3 such cultures, and they were your typical African/Amazonian/Aboriginal tribes that still live in near-neolithic conditi…

Clearly your father wasn't Scots

Re: Ibuprofen alters human testicular physiology

#195

Post by Toast_25 »

dzhiurgis wrote: post #159
darpa_escapee wrote: post #149

Earlier quoted context omitted.

I use CBD infrequently for pain. Chronic high CBD usage will result in withdrawal upon cessation. The 5HT1A agonism aspect of CBD makes for a particularly bleak and anxiety ridden withdrawal.

Not sure if it's CBD or THC, but coming off pot makes you realise how madly your REM sleep was disturbed (or basically non existent). Part of smoking pot I enjoy initially is amazingly deep sleep, but that can't be good in the long term.

Actually, you don't get REM when you smoke. That's why you don't dream and it's why it comes back full-swing when you stop. I occasionally smoke and drink (alcohol also disturbs REM quite a bit), but I try and do it early in the day so I can get quality sleep.

Re: Ibuprofen alters human testicular physiology

#196

Post by 52-6F-62 »

sreaching wrote: post #190
cookiecaper wrote: post #61

Earlier quoted context omitted.

Where can I read about "dropping male fertility" as a medical thing? Just taking a blind guess, as someone who doesn't follow the medical field, I would suggest that increases in "infertility" are much more likely to be caused by the older age at which people are becoming interested in "fertilization" than environmental factors causing biological malfunctions. In other words, it's not that reproductive systems are br…

testosterone levels have declined in most developed countries when comparing similar age cohorts over time. See the following studies: from Finland - https://www.ncbi.nlm.nih.gov/pubmed/23161753 . from USA - https://academic.oup.com/jcem/article/92/1/196/2598434 it is a bit of a medical mystery because the trend cannot be fully explained by lifestyle factors like weight gain.

This discussion came up sometime within the past few months. It was really interesting.

I recall mentioning some research into the effects of food/organics preservatives (namely Parabens) and low testosterone: https://www.ncbi.nlm.nih.gov/pubmed/12419695

Re: Ibuprofen alters human testicular physiology

#198

Post by Toast_25 »

bluedevil2k wrote: post #103
ardit33 wrote: post #23

If you hang around bodybuilding forums you will hear to avoid Ibuprofens as they hurt your ‘gains’ Perhaps bro-science was right in this case

Bodybuilders tend to not rely on their testes for testosterone production though

Not all bodybuilders juice, and even when they do, there's a wide variety of ways to increase your gains without straight up shooting testosterone.

Re: Ibuprofen alters human testicular physiology

#199

Post by Toast_25 »

saurik wrote: post #191
randallsquared wrote: post #173

Earlier quoted context omitted.

TIL that my pain is weak and mild, even when I think I'm in a lot of pain. I'm well over 200 lbs (still), but 200mg of ibuprofen usually eradicates whatever pain I have. If it's really bad pain, then I take 400mg.

TIL I have only experienced pain a few times in my life, and this apparently doesn't even include when I have had extensive dental work done as I don't let them give me any novocaine and don't mind them drilling into my teeth or cord packing my gums. I am really hoping that it isn't just that you all are like, five years older than I am, and so I have to expect that I am going to just end up in pain a lot soon :/.

I think it depends on the person, a friend of mine would act out WWE type stunts: jumping on a trampoline full of tacks, getting hit with a chair in the head and bleeding all over... He says the pain tolerance has stayed with him through the years.
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