181–190 of 640 posts
> When someone stops the medication, they'll usually regain the weight they lost Source? I agree that some people will regain the weight, but "usually" is an unfounded (without some data) generalization.
The problem (not new with GLP-1s) is that people lose weight, get life insurance, and then regain. The biggest part of that equation is regain part. Most people quit GLP-1s because of costs. Let's fix that.
I don't know, I tend to notice the effect wears off over time. Not sure it's a good idea to consume it permanently. Perhaps a better use would be for short periods to course correct.
Letting your weight fluctuate up and down in giant swings is, in many ways, harder on the body than just staying at a steady weight, even if it's overweight.
Predictions of when you will die need a range in order to be attached to a number like accuracy. The attached report is not about this but about population-level mortality trends.
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I'm just reporting my cached knowledge of people saying they experienced some adverse side effects. Also injections are not fun, even though they are probably a lot less annoying than they look.
A once-weekly subcutaneous injection is not a big deal for most people I think, outside of those who are very afraid of needles. It's a tiny needle and you don't even feel it. I've given injections to people who are afraid of needles, and they sometimes close their eyes in fear and are begging me to "just get it over with" without even realizing that I'm already done. Anyway, all this to say that outside of needle-ph…
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Would you say the same about blood pressure medications, diabetes medications, cholesterol medications, thyroid hormone replacement, antidepressants, mood stabilizers, antipsychotics, anti-anxiety medications, immunosuppressants, DMARDs, corticosteroids, anticonvulsants, Parkinson’s medications, multiple sclerosis treatments, blood thinners, and heart failure medications? All of them set people up for rebound failure…
I wouldn't group those together at all for the sake the argument. Take antidepressants for example. We're at the point of reexamining if we actually understand the consequences of long term usage of them. My personal experience was that my long term usage definitely came with issues and it's taken me a few years to feel like my emotional range has returned to a stabe baseline after going off them. I likely would have…
This is precisely what the FDA guidance contains: that GLP1s be mixed with lifestyle modifications.
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You’re thinking too highly about the incentives of the US healthcare system. Since insurance is tied to your employer (and therefore changing every few years), and most people die on Medicare, there’s not much incentive for insurance companies to pay for preventative care that won’t actually help you for several decades.
hmm...doesn't this possibly incentivize ozempic subsidies even more? If you know a "customer" of yours (an individual employee) is only going to be with you until they either change jobs or go on Medicare, then it seems the name of the game then is to make sure that nothing catastrophic happens to them until you can hand them off to someone else. In which case, they should definitely go on ozempic. Even if the effect…
The problem is, prediabetic and folks who may have crossed 7.0 A1C once, and just overweight folks with docs who are willing to play fast and loose are demanding it. Skipping metformin and other first line treatment options that are way cheaper. For those folks, complications might be the next guys problem.
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> admittedly, it kind of sucks in the moment to be on I don’t think that’s a typical experience for most people, other than the price
There's often side effects, including nausea, diarrhea, headaches, bloating, discomfort, etc. As far as I can tell from forums, it's not like 5% have the side effects, it's like 80-90%. But for the first time in decades, I felt full. I didn't want to finish a meal, it was too much. My body regulated my food intake in what felt like a natural way. I hadn't even realized my body had somehow lost that fundamental mechan…