Earlier quoted context omitted.
To make a generation ship work you have to build a self-contained ecology that is stable and self-repairing, inside mechanical and software systems that are fault tolerant and either extremely redundant or self-repairing, run by a political and social system that is also fault-tolerant and self-repairing. We know how to do exactly zero of those things.
There's a CRPG I've been meaning to play where this is basically the plot; there was a generation ship, it was heading towards some planet or another, but the social and political structure on the ship broke down at some point and now there's no one actually in charge, the ship is getting run down, and they probably blew past their destination a hundred years ago if they were even still on course at all. I remember s…
That isn't really different from the way things are now. We are, in fact, traveling through the galaxy for many generations and none of us signed up for it. We just happen to be on a largeish ship and have no destination.