Earlier quoted context omitted.
In practice probably not, as long as general population keeps it enabled. I mean, looking at effort required, it's not worth spending time exploiting spectre these days, because virtually everyone is protected. If you're not likely to be directly targeted, "herd immunity" will work.
If just visiting a webpage with some JS will let them do ACE on even 0.1% of visitors, hackers are probably still motivated enough to try it. But I vaguely remember these kinds of vulns can be patched in-browser for a perf hit instead of taking the hit system-wide, which sounds like an ok compromise. Edit: Arbitrary memory access, not ACE
The amount of actual exploit crafting that is needed to actually do something meaningful with a hack is pretty much not worth doing for any financial reason. The only time this happens now is when state funded actors or prominent groups with lots of manpower really want to take down an individual person.