Lots of people have a lot of negative stuff to say, but my take is: if you do psychedelics, you need to do the work and you need a firm ground before that. We have research that it might help with PTSD, depression, etc. but it's not like you just take it and you're done. It's a powerful substance and with power comes responsibility. I like to think of it more as an enhancer as to what's inside your head anyways. If that's fucked already, how are psychedelics gonna help you?
Psilocybin desynchronizes the human brain
181–190 of 276 posts
Re: Psilocybin desynchronizes the human brain
#182Lots of people have a lot of negative stuff to say, but my take is: if you do psychedelics, you need to do the work and you need a firm ground before that. We have research that it might help with PTSD, depression, etc. but it's not like you just take it and you're done. It's a powerful substance and with power comes responsibility. I like to think of it more as an enhancer as to what's inside your head anyways. If t…
> We have research that it might help with PTSD, depression, etc. but it's not like you just take it and you're done.
Worth noting the research is on psilocybin with supportive psychotherapy, not just take some mushrooms you got from a guy and have at it.
https://www.hopkinsmedicine.org/news/newsroom/news-releases/...
Re: Psilocybin desynchronizes the human brain
#183It's interesting that brain hypersynchronicity is a known source of epileptic seizures (among other things). This potentially could be a treatment for this specific problem. See e.g. * https://www.sciencedirect.com/science/article/pii/S089662731930964X * https://onlinelibrary.wiley.com/doi/full/10.1111/j.1528-1167.2010.02805.x
Doubtful. Shrooms cause seizures.
So do a lot of anti-epileptic drugs
Re: Psilocybin desynchronizes the human brain
#184Lots of people have a lot of negative stuff to say, but my take is: if you do psychedelics, you need to do the work and you need a firm ground before that. We have research that it might help with PTSD, depression, etc. but it's not like you just take it and you're done. It's a powerful substance and with power comes responsibility. I like to think of it more as an enhancer as to what's inside your head anyways. If t…
> We have research that it might help with PTSD, depression, etc. but it's not like you just take it and you're done. Worth noting the research is on psilocybin with supportive psychotherapy, not just take some mushrooms you got from a guy and have at it. https://www.hopkinsmedicine.org/news/newsroom/news-releases/...
Exactly what I was thinking about! There are some nice studies being done in Switzerland with a trip + 7 (I believe) sessions before and after
Re: Psilocybin desynchronizes the human brain
#185This is an interesting combination with this post from yesterday (Study reveals how anesthesia drug propofol induces unconsciousness): https://news.ycombinator.com/item?id=40981421
Their conclusion in that paper is that Propofol derails the brain’s normal balance between stability and excitability, which induces unconsciousness.
Re: Psilocybin desynchronizes the human brain
#186Earlier quoted context omitted.
I have a better idea: not even once.
I’ll back you up but having done shrooms about a dozen times decades ago, you’re really missing out on a truly out of this world experience.
Betting your life to get a hallucination is not worth it even at 1:10000 odds.
Guess what - you're missing out on a fentanyl high, so awesome that people sell all they have to get more!
Re: Psilocybin desynchronizes the human brain
#187Earlier quoted context omitted.
My brother has this permanently, though whether a delayed reaction to the booster or from when he got COVID itself (a relatively mild case) not long after, there's no way to know. It has been a major detriment to his day to day life though. Any physically involved hobbies are impossible; just walking up a flight or two of stairs now leaves him completely winded for several minutes, as his heart rate also takes longer…
Maybe it's running at high rate to compensate for some issue? An issue that could be found and resolved?
He's seen all the specialists. I think they ultimately came down on neurological damage, and tried a battery of drugs until they found some that slightly mitigated the problem. Last we talked about it, though, it hasn't been fully resolved.
Re: Psilocybin desynchronizes the human brain
#188Earlier quoted context omitted.
> I took a Pfizer COVID booster vaccine and saw my heart rate go up to resting above 100 Temporarily or permanently?
My brother has this permanently, though whether a delayed reaction to the booster or from when he got COVID itself (a relatively mild case) not long after, there's no way to know. It has been a major detriment to his day to day life though. Any physically involved hobbies are impossible; just walking up a flight or two of stairs now leaves him completely winded for several minutes, as his heart rate also takes longer…
That sounds like a relatively common Covid side effect.
Re: Psilocybin desynchronizes the human brain
#189Earlier quoted context omitted.
A user named observationist made a response to this post, but they responded to a troll, whose comment was nuked which removed their very valuable comment (I was responding to them at the time so I happened to have both in cache). observationist https://news.ycombinator.com/user?id=observationist original comment: Around 1% of people have schizophrenia. This holds over a lifetime - there's a structural, unavoidable c…
Isn't asking an LLM to find links that support an assertion equivalent to cherry picking sources? Also, just from a quick scan of some of these, it is apparent that the citations are not completely accurate. IMO, this is kind of asymmetric lazy commenting that wastes other peoples' time. If you want to share something, just link to a article, and leave the LLM bullshit out of it.
I appreciate the pushback on this process, it made me think.
I actually asked the LLM for supporting or refuting sources. I didn’t think I was cherry picking. Looking at its response… maybe CharGPT didn’t pick up on the “refuting” detail, or maybe observationist was correct. So maybe next time a prompt “find supporting” and another prompt “find refuting” would be useful to ensure coverage of both sides.
My value add in the human+AI workflow was to check the links. They seem high quality and directly applicable to statements made. I took pressure off observationist to go find directly applicable links (and I saved time by not googling for each separate fact). That being said, I probably didn’t need to requote ChatGPT in full. I liked the full answer because it assured me ChatGPT was responding on each claim but the important thing was the links. So, more efficiency was possible in my yc comment.
Re: Psilocybin desynchronizes the human brain
#190Earlier quoted context omitted.
Thanks for sharing. Not sure if the guidance to do shrooms in an appropriate setting and with an appropriate mindset ("set and setting") would have helped, but certainly that guidance is no joke! And we should absolutely continue research to learn more about the adverse effects. Obviously they help a lot of people, but must be done with care and seem not to be helpful for every person. We must learn more about these…
Whenever I read about shroom usage in ancient times, it almost always has some type of guidance and ceremony associated with it. The laws have turned it into something taboo and then people often start consuming psychedelics in a weird and suspicious way to begin with...because it's not legal potentially leading to more and more bad trips. Meditation is similar, often seemed to be associated with guidance from someon…
What is the name of the book?