Live data from Hacker News

MDMA and psilocybin are approved as medicines in Australia

wired.com

181–190 of 208 posts

Re: MDMA and psilocybin are approved as medicines in Australia

#181

Earlier quoted context omitted.

Why you sign your comments? Just genuinely curious.

Because they claim to have DID, and thus are saying that at that particular time, they are "fronting" with a persona they call Emily. FWIW, a large amount of the psychiatric establishment believes DID to not be real, per se. Instead they think it can be caused by an especially suggestible patient responding to a therapist or other psychiatric professional's coaching. Essentially playing a role in the therapy (for gen…

A number of studies indicate the prevalence of DID to be about 1% in the general population.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296396/#!po=1....

Re: MDMA and psilocybin are approved as medicines in Australia

#182
post #132
post #120

Earlier quoted context omitted.

Why wait til your older for those experiences? Those are wonderful ways to experience these drugs.

My life is not in order right now to make the best of those experiences. I'm working on it.

I feel you. More on the tea while camping… I found that a lovely afternoon in the park works too. It’s not the same as being in the woods, but it’s not like I feel like hiking while under the influence either. It’s fun to see other human in the distance, and when it winds down you can just go home walking. Nobody is the wiser, logistically easy.

Re: MDMA and psilocybin are approved as medicines in Australia

#183

This is fantastic! I am generally very pro-psychadelic - they seem like they can offer unique aid to people and they are not very prone to abuse. The only "downside" is that, because outcomes vary widely (though are generally not negative, simply unhelpful), it's hard to call them "medicine" in the way that, say, asprin is medicine. However, with the proper understanding, I'm hopeful they can be a really helpful tool…

There is already a proper understanding of them - they are pharmacologicaly super safe. Beyond that, they should be available for anyone to try, whether you "need" them or not, in non hero dose amounts, in therapy settings.

Yes that is what I am saying.

Re: MDMA and psilocybin are approved as medicines in Australia

#184

Earlier quoted context omitted.

Everything I've learned about therapeutic psilocybin treatment is that the doses involved are actually quite a bit higher than I've ever done on a trip at home. For example for psychedelic therapy with psilocybin, you would see a therapist a few times with no psilocybin, then you would have a session where you take something like the equivalent of 1 gram of dried mushrooms, and go through that session with the therap…

I've done a heroic dose without help, and it is very hard to describe. However, I'll describe one part: I went to the church of engineering and saw the manifest glory of all levels of abstraction that I understand and leverage to build _all_ at ONCE. I saw what I have been building in a new light ( https://www.adama-platform.com/ ). The absolute beauty of mathematics made me cry. Ever since this event, I have been...…

Yeah the experience I have with heroic doses of psilocybin and LSD have been both the most challenging and the most transformative. People are scared by the idea of a bad (scary/unpleasant) trip, but it's important to remember that the drugs will wear off, and you can often take some deep learnings about yourself from that unpleasantness.

Re: MDMA and psilocybin are approved as medicines in Australia

#185
post #122

Earlier quoted context omitted.

Everything I've learned about therapeutic psilocybin treatment is that the doses involved are actually quite a bit higher than I've ever done on a trip at home. For example for psychedelic therapy with psilocybin, you would see a therapist a few times with no psilocybin, then you would have a session where you take something like the equivalent of 1 gram of dried mushrooms, and go through that session with the therap…

5 grams? Most people would absolutely lose their shit on that. Even an eighth of good mushrooms is enough to obliterate most people. Like complete ego death. How long do these sessions last? What are the logistics? I’m very curious.

5g wet (fresh) of P. cubensis is totally doable. The same mass of dry *P. semilanceata* on the other hand...

Re: MDMA and psilocybin are approved as medicines in Australia

#186

Earlier quoted context omitted.

Because they claim to have DID, and thus are saying that at that particular time, they are "fronting" with a persona they call Emily. FWIW, a large amount of the psychiatric establishment believes DID to not be real, per se. Instead they think it can be caused by an especially suggestible patient responding to a therapist or other psychiatric professional's coaching. Essentially playing a role in the therapy (for gen…

A number of studies indicate the prevalence of DID to be about 1% in the general population. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296396/#!po=1....

Dissociative disorders in general, not DID in particular.

Re: MDMA and psilocybin are approved as medicines in Australia

#187

I still wouldn’t risk obtaining them legally, discretion is paramount for controversial medicine. One tiny data leak and your reputation is tarnished in certain circles, and that doesn’t even get into why the government knowing about it could be risky.

How could one possibly harm their reputation by using a legal medication

the most obvious example is people who still think it should be illegal and would look down on you for using it, it was never about the legality for them, the legality was just a side effect of their stance

Re: MDMA and psilocybin are approved as medicines in Australia

#188
post #122

Earlier quoted context omitted.

Everything I've learned about therapeutic psilocybin treatment is that the doses involved are actually quite a bit higher than I've ever done on a trip at home. For example for psychedelic therapy with psilocybin, you would see a therapist a few times with no psilocybin, then you would have a session where you take something like the equivalent of 1 gram of dried mushrooms, and go through that session with the therap…

5 grams? Most people would absolutely lose their shit on that. Even an eighth of good mushrooms is enough to obliterate most people. Like complete ego death. How long do these sessions last? What are the logistics? I’m very curious.

Yes my understanding was a that ego death is the goal, and this is done in a controlled setting with a trusted therapist.

I have no experience with these dosage levels but what I have heard is that some people don’t experience the full ego death at 3.5 grams but most people do at 5 grams, and I have also heard that there isn’t much additional effect from higher doses. So the thinking is to make sure to get everyone over that edge.

However there are other forms of treatment and I’m only talking about what I learned a few years ago, I’ve not studied the latest work and I am not a medical professional at all.

I did a quick google search to find more info for you and it seems there’s a lot of new work being done. I didn’t find any convenient link with the answer to your question though.

Re: MDMA and psilocybin are approved as medicines in Australia

#189

This is fantastic! I am generally very pro-psychadelic - they seem like they can offer unique aid to people and they are not very prone to abuse. The only "downside" is that, because outcomes vary widely (though are generally not negative, simply unhelpful), it's hard to call them "medicine" in the way that, say, asprin is medicine. However, with the proper understanding, I'm hopeful they can be a really helpful tool…

Um. No. Outcomes don’t “vary widely” Studies of Psilocybin treatments for depression show remarkable success rates. In some cases a single dose paired with one session of talk therapy provides relief for 3 months. Compared to the next most viable treatment SSRIs that take 3 weeks to start working and come with danger of opposite effects if the treatment is stopped. Studies using MDMA to treat PTSD work surprisingly well.

The few studies done on using those two drugs in psychiatric settings show phenomenally positive results. I don’t know where you’re getting your information from but it’s not by reading the scientific studies.

Re: MDMA and psilocybin are approved as medicines in Australia

#190

Earlier quoted context omitted.

A number of studies indicate the prevalence of DID to be about 1% in the general population. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296396/#!po=1....

Dissociative disorders in general, not DID in particular.

DID in particular is sampled at about 1%. I’ve included an excerpt from the previous link that states this. That paper seems to align with clinical perspective, as it’s the same number that McLean Hospital uses in their public communication. McLean is a psychiatric teaching hospital as part of Harvard Medical. It is one of the few organizations in the country that specializes in treating severe trauma disorders.

https://www.mcleanhospital.org/essential/did#:~:text=Myth%3A....

“Random samples of the general population in Canada and Turkey (female sample, 50% of whom were illiterate) found a life-time prevalence of DD of 12.2% and 18.3% respectively. A general population study in New York State found a 1-year prevalence of 9.1% for the DD.2,32,39 In Canada and New York, prevalence of DID was 1.3% and 1.5% of the population. In Turkey, the lifetime prevalence of DID was 1.1%”

Post reply on HN