Earlier quoted context omitted.
There will still exist a fascinating dichotomy, up until we can predict result without either simulation or animal models. An ideal engineered organism would be a delightfully weird homunculus, and a sufficiently advanced simulation could be deemed to be a living creature too. Perhaps it is best to make sure that lab technicians feel a great deal of empathy for the animals they work with.
Have to be careful, though. Too much empathy and you'll quit your job.
The lab technicians will after all be the experts on the subject; not academics on an ethics board.