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Seattle police use family DNA, latest science to identify killer 52 years later

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Re: Seattle police use family DNA, latest science to identify killer 52 years later

#181
post #178

Earlier quoted context omitted.

It is seriously not ok to be this aggressive or post personal attacks to HN. What incentive does anyone have to participate here if they're going to be harangued like this? Most people have genuine knowledge about the field in which they work, so harassing them about their employer is particularly counterproductive. If we allow commenters to disincentivize that, this place gets less interesting. Please review the gui…

Hey Dan. Do you agree that Anne Wojcicki is a very close personal friend of Sam Altman? What issues I have been discussing with my long time personal friend David here are inappropriate? Is ycombinator just a sham site to push BS and ban legitimate questions and calling out of scams, all in the service of market manipulation and PR? Please ban me Dan. It is long overdue and completely in line with Sam's agenda.

I don't know who Sam's friends are or how that would be relevant here.

If dahinds is your friend and I misread friendly banter as aggression, that's...far from what I was expecting to hear. But in that case your comments should include enough information to make it clear that they aren't the egregious violations of the site guidelines that they sounded like.

I don't want to ban you; I'd much rather persuade you to use HN in the spirit that it's intended. You've also posted some great comments, so that shouldn't be hard.

https://news.ycombinator.com/newsguidelines.html

Re: Seattle police use family DNA, latest science to identify killer 52 years later

#182
post #181

Earlier quoted context omitted.

Hey Dan. Do you agree that Anne Wojcicki is a very close personal friend of Sam Altman? What issues I have been discussing with my long time personal friend David here are inappropriate? Is ycombinator just a sham site to push BS and ban legitimate questions and calling out of scams, all in the service of market manipulation and PR? Please ban me Dan. It is long overdue and completely in line with Sam's agenda.

I don't know who Sam's friends are or how that would be relevant here. If dahinds is your friend and I misread friendly banter as aggression, that's...far from what I was expecting to hear. But in that case your comments should include enough information to make it clear that they aren't the egregious violations of the site guidelines that they sounded like. I don't want to ban you; I'd much rather persuade you to us…

As far as I know it wasn't friendly banter

Re: Seattle police use family DNA, latest science to identify killer 52 years later

#183

Earlier quoted context omitted.

You keep doubling down on this? The article says that DNA from the clothing sample was sent to Parabon for analysis in July of 2016, and was used in a GEDmatch search at that time. There's nothing remarkable about my claim, it is right there in the article. Also it simply isn't possible to submit a CODIS profile to GEDmatch, they only accept SNP array data, the matching algorithms only work for dense SNP array data,…

> specifically what it is you think 23andMe is doing that is improper 23andMe acquires, analyzes, stores, and trades in private medical data and does not comply with HIPAA in any way when doing so. We both know that the DNA data you have is personal medical data. You have a PhD and are an executive at one of the largest companies in the world that is trading in DNA data so we both know you are very aware this is true…

I don't really think you're trying to engage in a good faith discussion, but in case you are:

Lots of companies that handle medical information are exempt from HIPAA. "Many organizations that use, collect, access, and disclose individually identifiable health information will not be covered entities, and thus, will not have to comply with the Privacy Rule."[1] Generally many of our practices meet or exceed HIPAA requirements, either because we're complying with some other rule (like GDPR, or Common Rule for protection of subjects in research), or because we think we should.

You also still haven't given a specific example of something you think we're doing that you don't like. For example acquiring, analyzing and storing medical data is sort of required in order to provide our service to our customers so unless you think DTC genomics is fundamentally without merit this doesn't seem objectionable. If your concern is the "trades in" I think you may not understand exactly how we operate. Our privacy statement says we won't share even de-identified individual-level data without obtaining consent to do so. We rarely do that, for nearly all of our work, we only share statistical results from pooling information from thousands of individuals, where there is no way to extract data about any individual that contributed to the analysis.

As for the original article, I'll stake my professional experience that it's simply not technically possible to do a GEDmatch lookup using "reformatted" CODIS data from 2002. The article says that DNA was submitted to Parabon, not a CODIS profile, Parabon uses SNP arrays, GEDmatch uses SNP arrays, and if you think somehow they didn't in this instance you're frankly delusional.

There certainly are issues with testing old DNA samples and I'm not arguing about any of the difficulties with establishing chain of custody for old evidence, the complexity of statistics for CODIS matching, asserting guilt without a trial, etc. I haven't made any statements about any of that.

[1] https://privacyruleandresearch.nih.gov/pr_06.asp

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