I feel a lot of commenters are simply focusing on what signs can do or what sort of junction to build, rather than focus on the fact that on high speed primary country roads, bicycles shouldn't be sharing the road with the cars. In Denmark, a lot of high speed roads (excluding motorways, of course) out in the country have separate dual-way bicycle lanes near it but not attached to it. (Example: https://i.imgur.com/dS…
The drivers shouldn't be punished for bad design of the road. A separate bike road should be constructed.
The media has made a big deal about how tragic it is for the cyclists - which it is, but much less about how tragic it is for the driver. Remember, it's not like drivers want to hit cyclists or other soft traffic participants.
That's why I propose a separate bike road, even if it is quite an expensive undertaking. But it will make all the road users feel safe. Or -- at least -- safer.