Earlier quoted context omitted.
Yeah, I see the word "DX'ed" and immediately think of getting clotheslined by Triple H.
Now I'm even more confused. I can read every word in that sentence but I have no idea what it means.
Fecal transplants for autism deliver success in clinical trials (2019)
171–180 of 250 posts
Re: Fecal transplants for autism deliver success in clinical trials (2019)
#172Earlier quoted context omitted.
Study completed in 2022, but still no results posted or study published.
I've never really thought about this but, could it be because they don't want people to "try this at home"? Either because of safety issues, or my actual hypothesis, because they want to keep their possible pool of candidates as big as possible?
From the comments in the article above, it sounds like it may have failed it's primary outcome (autism symptoms). They only say there was significant benefit for "average of all symptoms", but it isn't clear if that is the same thing.
Re: Fecal transplants for autism deliver success in clinical trials (2019)
#173Many autistic children have extremely limited diets. For example, a geneticist friend of mine saw a case where an autistic child had been referred for genetic testing because of horrific, chronic, spontaneous wounds on gums and skin. Turned out to be scurvy, because he had exclusively eaten Wheat Thins for the last 3-4 years, which aren’t fortified with vitamin C. I would fully expect that a monotonous diet leads to…
Just to play devil’s advocate, isn’t it also possible that the preference for a monotonous diet is driven by gut makeup?
Re: Fecal transplants for autism deliver success in clinical trials (2019)
#174Earlier quoted context omitted.
Yeah, I see the word "DX'ed" and immediately think of getting clotheslined by Triple H.
Now I'm even more confused. I can read every word in that sentence but I have no idea what it means.
Re: Fecal transplants for autism deliver success in clinical trials (2019)
#175> Prior to the study, 83% of participants had "severe" autism. Two years later, only 17% were rated as severe, 39% as mild or moderate, and incredibly, 44% were below the cut-off for mild ASD. Pretty incredible if true!
I think the terminology of "incredible" is the operative word but I agree, if it could help, great. But I'm very skeptical. I find it hard to think that your gut biome can affect your brain so much that you struggle with social queues but are able to have an amazing memory. But then I've met people not on "the spectrum" who have an amazing memory, such as a professor I recently met with who could remember the page nu…
Maybe think of this as removing a long-standing distraction or irritant. Like turning down the music from 120 decibels to 80 while you're trying to work.
Re: Fecal transplants for autism deliver success in clinical trials (2019)
#176Many autistic children have extremely limited diets. For example, a geneticist friend of mine saw a case where an autistic child had been referred for genetic testing because of horrific, chronic, spontaneous wounds on gums and skin. Turned out to be scurvy, because he had exclusively eaten Wheat Thins for the last 3-4 years, which aren’t fortified with vitamin C. I would fully expect that a monotonous diet leads to…
Just to play devil’s advocate, isn’t it also possible that the preference for a monotonous diet is driven by gut makeup?
Re: Fecal transplants for autism deliver success in clinical trials (2019)
#177> my deepest fantasy is that one day I'll be in the hospital for some random thing, they'll take blood for some test, and then when they read the results, their eyes will go wide and they'll call for a consult. The other doctor will read the results and say "you don't have the nutrient?! How do you live? You're so brave". They give me a shot, and just like that, I'm able to conduct myself in society, understand social cues, hold my attention on anything i want for any length of time, etc
... so perhaps the Nutrient is a product of a gut bacterium.
Re: Fecal transplants for autism deliver success in clinical trials (2019)
#178Re: Fecal transplants for autism deliver success in clinical trials (2019)
#179Earlier quoted context omitted.
I think the terminology of "incredible" is the operative word but I agree, if it could help, great. But I'm very skeptical. I find it hard to think that your gut biome can affect your brain so much that you struggle with social queues but are able to have an amazing memory. But then I've met people not on "the spectrum" who have an amazing memory, such as a professor I recently met with who could remember the page nu…
You should read up - you're pretty obviously misunderstanding the diagnosis. Maybe think of this as removing a long-standing distraction or irritant. Like turning down the music from 120 decibels to 80 while you're trying to work.
I'm struck by this quote, which I'd be surprised if they could be explained fully by the distraction-reduction mentioned:
> "Evaluation of symptoms on the Parent Global Impressions found that the treatment group at the end of part 2 improved more than the placebo group in part 1 on nearly all symptoms, with statistically significant improvements in GI, receptive language, and average of all symptoms. There were also marginally significant improvements in tantrums, stimming/perseveration, and cognition."
Re: Fecal transplants for autism deliver success in clinical trials (2019)
#180Many autistic children have extremely limited diets. For example, a geneticist friend of mine saw a case where an autistic child had been referred for genetic testing because of horrific, chronic, spontaneous wounds on gums and skin. Turned out to be scurvy, because he had exclusively eaten Wheat Thins for the last 3-4 years, which aren’t fortified with vitamin C. I would fully expect that a monotonous diet leads to…
Just to play devil’s advocate, isn’t it also possible that the preference for a monotonous diet is driven by gut makeup?
just to play devil's advocate that it isn't an opposing possibility