Earlier quoted context omitted.
No. The drug warriors are neither humane nor sensible. Opioids are actually not all that dangerous, but the range between high and dead is not all that great. When you know what you're getting (chronic pain patients) the problem rate is low. But with the street you get varying purity. And the drug war has caused the manufacturers to move to more concentrated products to make smuggling easier. And fentanyl has a very…
> No. The drug warriors are neither humane nor sensible. I never once advocated for the war on drugs approach, and I made that crystal clear in my comment. Proper policy != war on drugs. It means making sure that drugs get properly certified and its distribution controlled. It means focusing on treatment rather than aggressively punishing those who get addicted. It means addressing the underlying social issues that p…
Opioids are only dangerous due to variance in purity (overdoses) and availability (withdrawal-motivated crime).
Of course addiction and dependence can be exploited for profit, but how is opioid dependence different in that respect from alcohol dependence, gambling addiction, sex addiction or even TikTok?
We already know what causes compulsive behaviors linked to addictions and also how to undo them. Amphetamines, cocaine, opioids, gambling and sex have a common denominator, namely overexpression of Delta-FosB protein in the orbitofrontal cortex. Those changes can be eradicated overnight with histone deacetylase inhibitors, but this treatment is not generally available.