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Fasting boosts stem cells’ regenerative capacity (2018)

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Re: Fasting boosts stem cells’ regenerative capacity (2018)

#171

Earlier quoted context omitted.

Not sure why I’d pass out from just not eating, I had plenty of body fat on me for the entirety of the fast. I wasn’t starving myself. Estimating by weight loss my metabolism was still burning well over 2500kcal daily at the end of the fast.

Agreed. Pretty much my numbers as well - around 300 gr weight loss a day. An example: A person with 14 % body fat and 74 kg body weight has around 10 kg fat. That is more than enough to go for about 30 days without any calorie intake.

Yeah, my weight loss was around 1.3 lbs or 600 grams daily. I'm a large human though.

Re: Fasting boosts stem cells’ regenerative capacity (2018)

#172
post #22

It's such a shame that there isn't more research in this area. There are so many seemingly wondrous effects on human health that would need thourugh testing. Apart from physiological benefits though, the mental aspect of fasting from my own experience can be quite exciting as well. A 7 day fast was the longest I did so far, but 72h really hit the sweet spot for me. It was like a journey through my mind, I got challen…

I really think a 7 day fast should be 'mandatory reading' as far as life experience goes. You learn a lot about yourself. Also echo the mental clarity side of fasting. The weight loss was great, but how I felt was even better. The crazy thing is, if you can get to 7 days, anything past that is just mental and you can go as long as you have the body fat to sustain the fast, provided you're keeping an eye on your elect…

I would say there are some things to watch for if doing long term fasts, one is salt and potassium levels to prevent heart attacks, especailly true for those of us who are on the larger side, and especially as one get's closer to say the 20 day mark. A week or two probably wouldn't kill anyone if they have the fat stores, but a heart attack prompted by lack of salts is a potential concern.

Re: Fasting boosts stem cells’ regenerative capacity (2018)

#173
post #22

It's such a shame that there isn't more research in this area. There are so many seemingly wondrous effects on human health that would need thourugh testing. Apart from physiological benefits though, the mental aspect of fasting from my own experience can be quite exciting as well. A 7 day fast was the longest I did so far, but 72h really hit the sweet spot for me. It was like a journey through my mind, I got challen…

>It's such a shame that there isn't more research in this area. From what I've seen there is actually research into it and the weight loss/fitness benefits don't seem to be any better than any other calorie restriction when equating calories (slightly worse for muscle mass when combined with exercise in one study IIRC), and other claims seem overblown. Layne Norton has a couple of good study reviews (eg. https://www.…

You're right, the weight loss per calorie restricted is about the same. That's not the point, it's about feeling better, being healthier and for IF, the lifestyle makes it easier to manage your sugar intake, calorie intake and overall health.

Re: Fasting boosts stem cells’ regenerative capacity (2018)

#174
post #28

Earlier quoted context omitted.

I did a 7 day fast, and I mostly ended up losing fat. While I did not do any scientific measurement, i was able to exercise the same post the 7 day fast and my belly fat came down big time. Maybe body builders lose lean body mass when they fast, but it does not seem to hold true for the average human.

You have mostly lost water to be precise. As well as muscle. You need an expensive Dual-energy X-ray absorptiometry scan in order to precisely tell the body mass composition.

If you can't get a DEXA scan there is an equation published in December of 2021 which approximates it well:

The new equation [%BFNew = 6.083 + (0.143 × SSnew) - (12.058 × sex) - (0.150 × age) - (0.233 × body mass index) + (0.256 × waist) + (0.162 × sex × age)] explained a significant proportion of variance in %BF5C (R2 = 0.775, SEE = 4.0%). Predictors included sum of skinfolds (SSnew, midaxillary, triceps, and thigh) and waist circumference. The new equation cross-validated well against %BF5C when compared with other existing equations, producing a large intraclass correlation coefficient (0.90), small mean bias and limits of agreement (0.4% ± 8.6%), and small measures of error (SEE = 2.5%).

Generalized Equations for Predicting Percent Body Fat from Anthropometric Measures Using a Criterion Five-Compartment Model Zackary S Cicone, Brett S Nickerson 1, Youn-Jeng Choi 2, Clifton J Holmes 3, Bjoern Hornikel 4, Michael V Fedewa 4, Michael R Esco 4 Affiliations expand PMID: 34310492 PMCID: PMC8785250 (available on 2022-12-01) DOI: 10.1249/MSS.0000000000002754

https://pubmed.ncbi.nlm.nih.gov/34310492/

Re: Fasting boosts stem cells’ regenerative capacity (2018)

#175
post #173

Earlier quoted context omitted.

>It's such a shame that there isn't more research in this area. From what I've seen there is actually research into it and the weight loss/fitness benefits don't seem to be any better than any other calorie restriction when equating calories (slightly worse for muscle mass when combined with exercise in one study IIRC), and other claims seem overblown. Layne Norton has a couple of good study reviews (eg. https://www.…

You're right, the weight loss per calorie restricted is about the same. That's not the point, it's about feeling better, being healthier and for IF, the lifestyle makes it easier to manage your sugar intake, calorie intake and overall health.

Sure, but I think there were some studies that looked at adherence and it didn't seem different to other diets there as well - but I could be misremembering.

That being said - this is highly individual stuff - even if something doesn't work for 99% of people - it doesn't matter if it works for you - and it's easy to try.

It's just important to have realistic expectations about these things, because overhyping tends to lead to motivation spikes - you get enthusiastic and then you get disappointed and crash to 0.

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