Live data from Hacker News

Evaluating necessity of Covid-19 vaccination in previously infected individuals

medrxiv.org

171–180 of 361 posts

Re: Evaluating necessity of Covid-19 vaccination in previously infected individuals

#171
post #166
post #149

Earlier quoted context omitted.

That does not conflict with being unbiased towards evidence that our immune systems are effective against covid.

As long as the initial infection didn’t kill or incapacitate you. Edit: most bubonic plague infections didn’t kill so I don’t know what the point of “most people survive” is. The problem is that some don’t.

Which is most of covid infections.

Re: Evaluating necessity of Covid-19 vaccination in previously infected individuals

#172
post #137

This is really good news. Whenever I see people talking about if previously infected people should be vaccinated, they always mention how we don't know how long protection lasts for previously infected people. This study includes this section: Duration of protection This study was not specifically designed to determine the duration of protection afforded by natural infection, but for the previously infected subjects…

Most “previously infected” people were absolutely not infected at all. If this study involved self-reported previously infected and not confirmed PCR, the results would be very different.

Re: Evaluating necessity of Covid-19 vaccination in previously infected individuals

#173

Punchline: “The cumulative incidence of SARS-CoV-2 infection remained almost zero among previously infected unvaccinated subjects, previously infected subjects who were vaccinated, and previously uninfected subjects who were vaccinated, compared with a steady increase in cumulative incidence among previously uninfected subjects who remained unvaccinated. Not one of the 1359 previously infected subjects who remained u…

It’s really, really problematic this study used a hospital database of PCR test results, instead of self-reporting. This study will go viral and every yokel who was on the fence but had flu symptoms back in July will decide they don’t need the vaccine.

Re: Evaluating necessity of Covid-19 vaccination in previously infected individuals

#174
post #28

Earlier quoted context omitted.

That's encouraging! I got COVID a few months ago and got vaccinated recently, seems like I should be unstoppable now.

Hey I'm curious, if you don't mind sharing, how do you think you got it? Throughout this whole pandemic, I'm still kind of amazed how people are getting it

I caught it from sharing a thirty minute meal with an in-law who didn't divulge that she had attended a party and had woken up coughing that day.

Re: Evaluating necessity of Covid-19 vaccination in previously infected individuals

#175
post #65
post #57

Earlier quoted context omitted.

> I don't see how public health would benefit from not recommending shots to everyone as there is no downside. You'd get all the never infected people vaccinated sooner; so 'everyone' (except anti-vax not infected prior to effective 'herd immunity') would be immune sooner.

Yeah, in theory that would be the obvious advantage. In practice, don't underestimate how much more inefficient or troublesome a seemingly simple additional rule or exception might be to administer... :P

This guy secures.

Re: Evaluating necessity of Covid-19 vaccination in previously infected individuals

#176

Earlier quoted context omitted.

Because openly stating this obvious fact would get you downvoted on here a few months ago.

> Because openly stating this obvious fact would get you downvoted on here a few months ago. Attempting to discuss it here will still commonly get you downvoted. HN is not a particularly rational forum. People make the mistake of thinking it is because a lot of engineers hang out here. Engineers are not especially rational, that's a common myth derived from failing to understand the way people mentally compartmentali…

I’d love to see real numbers of how many people have been infected, but I have no idea how you would get them. Do you have any suggestions?

Re: Evaluating necessity of Covid-19 vaccination in previously infected individuals

#177
post #28

Earlier quoted context omitted.

That's encouraging! I got COVID a few months ago and got vaccinated recently, seems like I should be unstoppable now.

Hey I'm curious, if you don't mind sharing, how do you think you got it? Throughout this whole pandemic, I'm still kind of amazed how people are getting it

I caught it when I got my car’s oil changed.

Re: Evaluating necessity of Covid-19 vaccination in previously infected individuals

#178
post #21

Any other result would have been surprising. Why is this interesting, beyond just confirming what we were already 99.99% certain we knew? -- biochemist

Most authorities are downplaying natural immunity, despite evidence like this. The more widely this spreads, the more people will realize it's ok to rely on natural immunity, and to not blanket demonize those who are unvaccinated.

I can imagine it being downplayed out of fear that it could slow down the vaccination program by pushing people over the edge that were hesitant to get vaccinated and possibly questioning covid-19 in the first place.

Re: Evaluating necessity of Covid-19 vaccination in previously infected individuals

#179

I did have covid (not diagnosed while active but shown in antibody test), and I got vaccinated significantly later. This was not driven by belief in medical need, but by social/rules need. You get no "points" for being recovered like you do for a proof of vaccination.

Same. Covid in January, J&J a few weeks ago. I don't really think it was necessary, but the risk of taking it balanced out the risk of reinfection, both of which seemed really low.

Re: Evaluating necessity of Covid-19 vaccination in previously infected individuals

#180

Earlier quoted context omitted.

Most authorities are downplaying natural immunity, despite evidence like this. The more widely this spreads, the more people will realize it's ok to rely on natural immunity, and to not blanket demonize those who are unvaccinated.

The unvaccinated are still vectors for the infection of those who cannot be vaccinated, such as the immunocompromised. I personally don't think in terms of "blanked demonizing" people, but neither am I going to blanket-absolve all the unvaccinated — especially willful anti-vaxxers. Regardless, this study is good news — because it means that every person who is infected and then recovers contributes towards herd immun…

> The unvaccinated are still vectors for the infection of those who cannot be vaccinated, such as the immunocompromised

Is it actually the case that immunocompromised people cannot be vaccinated? The ones that I know have been; as far as I know, the mRNA vaccines by virtue of not being based on live virus are not dangerous to those with weakened immune systems.

Post reply on HN