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Pfizer submits Covid vaccine to FDA for approval, to distribute in December

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Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#171

Post by peteradio »

ghaff wrote: post #97
solarhoma wrote: post #44

Earlier quoted context omitted.

Do you think private companies will require vaccination to return to work? *Here is an article I found on the subject. Essentially stating in general employers could require vaccination. https://www.usatoday.com/story/money/2020/08/26/coronavirus-...

I fully expect that once it is widely available (major caveat), many workplaces and schools will require it absent medical exceptions. Certainly, most schools require vaccinations today and I don't expect there will be a lot of sympathy for those that want to hold off.

Most schools require vaccines which have been in circulation for a long long time and presumably whose long term risks are well understood. I think it would be pretty stupid to force mass vaccinate such a rushed vaccine, don't you think?

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#172

Post by anonuser123456 »

gvv wrote: post #29

Well just like I don't immediately update to the latest OS I think I'll wait for the beta testing to happen :)

On a risk basis, it’s clearly better to get the shot than COVID. But you aren’t wrong in you belief the vaccine may have unknown side effects. The trails were not powered to find the 1 in 10000 side effects that pop up. We won’t know those for months.

Not that you’ll be able to get the vaccine for months anyway, unless you work in healthcare.

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#173

Post by kilbuz »

koalala wrote: post #116
refurb wrote: post #61

Earlier quoted context omitted.

As someone who has some experience with clinical trials and drug approvals, I'd be quite comfortable taking the vaccine. A clinical trial size of 40,000 (20,000 receiving the vaccine) is way larger than a lot of other drugs that people are comfortable taking. Is there zero risk of serious side effects? Of course not, there never is. But the trial gives enough data to say the risk is worth the benefit. Edit: The FDA h…

can you give an example of popular drugs that have been approved with smaller trials?

I have never personally seen a randomized study with anywhere near 40k+ participants for any cardiology or cancer-related treatment. Recruitment for this vaccine trial is much easier than studies with specific conditions like heart attack, stroke, or cancers, simply due to their incidence rates. In cardiology, a 20k subject study is massive in scale.

All this to say that for the pivotal phase 3 trials submitted to FDA for approval, I would suppose almost all existing drugs had much fewer than 40k participants.

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#174

Post by singemonkey »

lmilcin wrote: post #88
iakh wrote: post #79

Earlier quoted context omitted.

[flagged]

Hey. I am not anti vaccine. Your comment is uninformed in that you did not read my comment with comprehension and that you don't understand what stupid stuff anti-vaxxers are serving. My kids are all vaccinated and so am I and I don't suggest to people to not vaccinate. I am just trying to cool down the too happy thinking that the vaccine is some magical tool that automatically causes problems to go away with no risk…

Thea audacity of over-confident ignorance never fails to surprise me.

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#175

Post by bluGill »

fairity wrote: post #105
amelius wrote: post #70

Did they publish the mRNA code?

Isn’t it pretty easy to sequence anyways? Assuming you can get a hold of a vaccine sample.

Probably, but why bother. If you have the ability to do that, you also have the Covid DNA sequence, and probably the ability to make your own mRNA vaccine. The only thing your vaccine would be lacking is the safety trials which you probably also have the ability to run, and you have already started them (if you haven't why not, and why would you care to start now).

There is the possibility that you have the ability to manufacture mRNA in your factory but didn't have the idea to start making your own vaccine until late enough that it wasn't worth trying to make your own. In this case you may want to talk to Pfizer about licensing their (but you have probably been in those talks for months and are just waiting for the right time to publicly announce the deal with production already started)

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#177

Post by [deleted] »

jdndbfbf wrote: post #169
bluGill wrote: post #154

Earlier quoted context omitted.

I'll take my chances. My sister-in-law is dead. A brother-in-law is still unsure if we can talk across a room without fainting (6 months ago he was running several miles a day). This is just in my tiny circle of close family. Thousands in a much larger sample of had the vaccine with no side effects anywhere near that bad.

n=1 is irrelevant I don't care about one persons experiences.

[deleted]

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#178

Post by splaytreemap »

jbd28 wrote: post #22
qwerty456127 wrote: post #16

Earlier quoted context omitted.

Despite being extremely pro-vac I'm going to postpone getting vaccinated with this for as long as possible (at least a couple of years hopefully). Even if they would disallow me to travel abroad I would rather stay in my home country. I've heard about a guy who volunteered to try the Russian vaccine - he got extremely sick and almost died from inflammatory cardiomyopathy as the result. So I want to see thousands of p…

This isn’t a mid 2000s windows OS update. Don’t be part of the problem, take the shot and grow up

Implying people are children for holding different views than you is way less persuasive than you seem to think it is.

Re: Pfizer submits Covid vaccine to FDA for approval, to distribute in December

#180

Post by hobby-coder-guy »

jdndbfbf wrote: post #169
bluGill wrote: post #154

Earlier quoted context omitted.

I'll take my chances. My sister-in-law is dead. A brother-in-law is still unsure if we can talk across a room without fainting (6 months ago he was running several miles a day). This is just in my tiny circle of close family. Thousands in a much larger sample of had the vaccine with no side effects anywhere near that bad.

n=1 is irrelevant I don't care about one persons experiences.

Why are you a dickhead?
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