171–180 of 700 posts
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They'd be so much more successful, if "Install" button did not have this: wget https://cloudron.io/cloudron-setup chmod +x ./cloudron-setup ./cloudron-setup --provider [digitalocean,ec2,generic,ovh,...]
Is that any less secure than “sudo dpkg -i foo.deb”?
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I want to believe... I always thought WebAssembly had a lot of potential, however, in practice it doesn't seem to have turned out that way. I remember the first Unity demos appearing on these orange pages at least 4 or 5 years ago, and promptly blowing me away. But, after an eternity in JavaScript years, I still dont know what the killer app is, technically or business wise. (Side note - I encourage people to prove m…
> I'd love to see examples of what WebAssembly makes possible that wouldn't exist without it. I've been playing with WebAssembly lately and the moment where it clicked for me how powerful it was was building an in-browser crossword filler ( https://crossword.paulbutler.org/ ). I didn't write a JS version for comparison, but a lot of the speed I got out of it was from doing zero memory allocation during the backtracki…
I recently wondered if you can take your saliva, or blood, and get a diffraction scan of it. Kind of like a spectrograph. You’d feed this into a machine learning system, and it would match up your pattern against a known dataset. This might allow for faster identification and recognition, of known viruses and diseases. Especially if the technology can identify the virus from just your spit.
Current methods can pretty easily identify the virus from just your spit (in fact, that's a protocol that is pretty widely used for different applications). The biggest problem is that normally you need to concentrate the virus in order to get detectable range for earlier days of infection. Seems like the range is approximately ~2 days earlier with concentrating vs spit only, which is actually significant. All diseas…
But then for most things .. the problem is the prep, not just because the whole portability thing goes for a toss. Yay, great the sequencer is the size of a USB drive, but the rest of the lab isn't :/
More worryingly the biggest and most stubborn cost is now the prep, not the sequencing.
As you correctly pointed out - need to find a way around amplification - then both of these problems above go away if you can do direct PCR free sequencing.
The other less mentioned problem related to the above is also the need for parallelisation - some of those ultra low costs you read about can only be realised when you sufficiently multiplex your samples. For instance, its about 100 USD per reaction for ligation (last step of prep before the sequencing starts), you generally wait till you're sequencing atleast 12 samples in the same reaction so that you're paying <10$ per sample, not 100$ per sample, which is obviously insane.
Things like
- When will this company raise the next round? - What is the net worth of ? - What is the probability that this investor will invest in you? (given your sector, founder age, pedigree, gender, market conditions, do you have an MVP or not etc.) - A bunch of other complicated stuff I didn't really understand
Definitely worth keeping an eye on if you're into this kinda stuff: https://coscout.com/
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That potentiality has been there for many many years, I don't see 'the thing' that provides the critical mass necessary to make it work in reality. Web Assembly is one of the more misunderstood technologies in terms of it's real, practical application. At its core, it crunches numbers, in limited memory space. So this can provide some 'performance enhancements' possibly for running some kinds of algorithms. It means…
I think you're underestimating WASI. Projects like cloudABI, where an existing app is compiled against a libc with strong sandboxing, really cool things happen.
For 5 years we've been hearing about how great they are, except nobody is really using them.
So now, it's 'the next thing' that will make it great? Except that next thing isn't there, not agreed upon or implemented, we don't know so many things about it?
Like I say, this is textbook example of tech-hype for things probably not as valuable as they appear.
If (huge if) WASI were 'great, functional, widespread, smoothly integrated' - I do agree there's more potential. But that this will really happen is questionable, and that even if it does happen, it will be valuable, is questionable.
Web Assembly It's interesting in a bunch of ways, and I think it might end up having a wider impact than anyone has really realized yet. It's an ISA that looks set to be adopted in a pretty wide range of applications, web browsers, sandboxed and cross platform applications, embedded (into other programs) scripting, cryptocurrencies, and so on. It looks like it's going to enable a wider variety of languages on the web…
Even if it were, there is an extremely high bar to meet for actual new ISAs/cores. There is no chance for Wasm to compete with RISC-V, Arm or x86.
NextDNS (nextdns.io) is a genius idea that I very much wish I had thought of. I am a paying customer as of this past week and am integrating it in all the places I always meant to put a pihole ...