Psilocybin found safe for consumption in largest ever controlled study • Hacker News Board

Re: Psilocybin found safe for consumption in largest ever controlled study

#171

Post by semi-extrinsic » Fri, Jan 03, 2020, 7:37 AM UTC

dmurray wrote: post #72

semi-extrinsic wrote: post #54

Earlier quoted context omitted.

Why shouldn't there be a placebo effect? It's well documented for basically any drug, even for alcohol. Serve people non-alcoholic drinks but tell them otherwise, and they get drunk.

Because the trial wasn't about finding the expected effect (drunkenness) but the secondary effects. People don't get heart disease or cirrhosis from non-alcoholic drinks, or at least, I'd be interested in reading the study where they do.

No, but they can get short-term secondary effects such as nausea, headaches the next day, etc. Probably this category of things is what they want to control for.

Re: Psilocybin found safe for consumption in largest ever controlled study

#172

Post by malux85 » Fri, Jan 03, 2020, 7:43 AM UTC

loeg wrote: post #159

coffeemug wrote: post #130

Counter-anecdote: I've experimented with this stuff extensively in various settings and have known many other people who did, and in my experience it's unequivocally bullshit. Here's what happens. First, any given trip alleviates depression for about a month or two. That makes sense to me in a sense that the word "trip" isn't a coincidence-- a really fun intense vacation in a foreign country also alleviates depressio…

That's a hell of a generalization from an anecdote.

I know right - it's an epic extrapolation.

I drank a beer 20 years ago and now BAM, cancer. We should ban all this cancer causing beer.

Re: Psilocybin found safe for consumption in largest ever controlled study

#173

Post by taurath » Fri, Jan 03, 2020, 9:08 AM UTC

shlant wrote: post #150

chronofar wrote: post #148

Earlier quoted context omitted.

First of all, there is a wide delta of difference between taking these substances recreationally and in a clinical setting. Any clinician involved with these trials is not going to equivocate their use in treating depression with your weekend in the woods with your friends. Second if we are talking recreationally I have met many, many people on a third path there: the understanding that psychedelics offer a beautiful…

> "I believe your cynicism has sliced off only a portion of the truth here and tilted focus in the wrong directions." I think his cynicism is completely warranted considering how many people are starting to view psychedelics as a panacea. Do psychedelics offer an experience that could be part of, or even a spark a greater shift? Sure. Could psychedelics provide temporary relief from things like depression and anxiety…

I haven't heard almost anyone say its a panacea, but are still advocating for their consideration as there's plenty of people who will advocate its always a bad idea.

Re: Psilocybin found safe for consumption in largest ever controlled study

#174

Post by lowdose » Fri, Jan 03, 2020, 9:10 AM UTC

malux85 wrote: post #167

coffeemug wrote: post #130

Counter-anecdote: I've experimented with this stuff extensively in various settings and have known many other people who did, and in my experience it's unequivocally bullshit. Here's what happens. First, any given trip alleviates depression for about a month or two. That makes sense to me in a sense that the word "trip" isn't a coincidence-- a really fun intense vacation in a foreign country also alleviates depressio…

No, your conclusion is bullshit. > First, any given trip alleviates depression for about a month or two. That makes sense to me in a sense that the word "trip" isn't a coincidence-- a really fun intense vacation in a foreign country also alleviates depression for a month or two. You swear that when you come back things will be different, but then you have to answer slack messages at 9pm, and your project is slipping…

Brutal honesty at its best. If everyone had the guts to talk this tone to their boss the world would look a lot better.

Re: Psilocybin found safe for consumption in largest ever controlled study

#175

Post by uyuioi » Fri, Jan 03, 2020, 9:20 AM UTC

Always safe. Only it can’t be patented is why you never got it!

Re: Psilocybin found safe for consumption in largest ever controlled study

#176

Post by mda » Fri, Jan 03, 2020, 9:25 AM UTC

lowdose wrote: post #174

malux85 wrote: post #167

Earlier quoted context omitted.

No, your conclusion is bullshit. > First, any given trip alleviates depression for about a month or two. That makes sense to me in a sense that the word "trip" isn't a coincidence-- a really fun intense vacation in a foreign country also alleviates depression for a month or two. You swear that when you come back things will be different, but then you have to answer slack messages at 9pm, and your project is slipping…

Brutal honesty at its best. If everyone had the guts to talk this tone to their boss the world would look a lot better.

Well there is a saying "It is easy for a single man to divorce a wife". I am not sure his suggestion is practical also tone is terrible. I hope they can cope with other people who are being "brutally honest" with them being a jerk in real life.

Re: Psilocybin found safe for consumption in largest ever controlled study

#177

Post by lowdose » Fri, Jan 03, 2020, 9:30 AM UTC

mda wrote: post #176

lowdose wrote: post #174

Earlier quoted context omitted.

Brutal honesty at its best. If everyone had the guts to talk this tone to their boss the world would look a lot better.

Well there is a saying "It is easy for a single man to divorce a wife". I am not sure his suggestion is practical also tone is terrible. I hope they can cope with other people who are being "brutally honest" with them being a jerk in real life.

I read love your wife more in the morning because her soliciting other guys in front of you is the most obvious sign she will give before filing for a divorce herself.

If no one tells you this , you can't solve problem number one. Problem number one always results in no sex followed by a system break down hence the princess comment. In the western society women initiate 2/3 of the divorces.

GP is nuanced giving a helicopter view on the personal projection at hand so it doesn't dilute the actual news brought here to light . If this tone sounds offensive we could ask HN to introduce emojis.

Someone once said something about a hammer the same applies for the mushroom.

Edit: your original comment included in Turkey we have a saying.

Re: Psilocybin found safe for consumption in largest ever controlled study

#178

Post by karpodiem » Fri, Jan 03, 2020, 9:33 AM UTC

coffeemug wrote: post #130

Counter-anecdote: I've experimented with this stuff extensively in various settings and have known many other people who did, and in my experience it's unequivocally bullshit. Here's what happens. First, any given trip alleviates depression for about a month or two. That makes sense to me in a sense that the word "trip" isn't a coincidence-- a really fun intense vacation in a foreign country also alleviates depressio…

Take the red pill - go to the gym and get jacked. It will solve many of your problems.

Re: Psilocybin found safe for consumption in largest ever controlled study

#179

Post by Fnoord » Fri, Jan 03, 2020, 9:37 AM UTC

mothsonasloth wrote: post #35

ianai wrote: post #21

Earlier quoted context omitted.

I’d steer you toward kava kava as a legal and otc way to change your mind and emotions for the better or more open. Also St. John’s wort.

After googling, it appears that kava causes liver damage, thanks but no thanks

1 minute on Wikipedia told me it is only the root which is edible, the rest is extremely toxic and causes liver damage.

Re: Psilocybin found safe for consumption in largest ever controlled study

#180

Post by Erlich_Bachman » Fri, Jan 03, 2020, 9:43 AM UTC

01100011 wrote: post #163

coffeemug wrote: post #130

Counter-anecdote: I've experimented with this stuff extensively in various settings and have known many other people who did, and in my experience it's unequivocally bullshit. Here's what happens. First, any given trip alleviates depression for about a month or two. That makes sense to me in a sense that the word "trip" isn't a coincidence-- a really fun intense vacation in a foreign country also alleviates depressio…

IME, my various neuroses are correlated with my productivity. Sure, I can eat shrooms and feel better, but I'm too happy and mellow to get anything done. Soon, the stress from not keeping up builds and I'm back on the wheel again. I did have some luck using mild amounts to combat the negative cognitive effects of smoking too much pot(mostly verbal deficiencies), but in the end it was better to just stop smoking pot.…

> Sure, I can eat shrooms and feel better, but I'm too happy and mellow to get anything done.

That should tell you about the true nature of your motivation.

If you are only productive when you are unhappy, it likely means that you are trying to motivate yourself with negative thoughts and judging and compulsive feelings, it means you do productive things while using a stick to constantly keep yourself in fear of hitting yourself with it if you're not productive. If anything, this is the message the mushrooms are trying to tell you. But it is still up to you to change your patterns in response to that message.