From the viewpoint of a space colony food is a renewable resource as after humans “consume” the food the food is now CO2 and other waste products. Martians may vent CO2 but I’d think asteroid colonists would seek to recycle every bit of volatile that they can.
A standard mechanical vacuum pump can reach 1/1000th of an atmosphere, so in theory this scheme should be able to reduce leak rates to only 1/1000th that of an equivalent single-hull design.