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Fentanyl vaccine tested in rats

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Re: Fentanyl vaccine tested in rats

#161

Post by cstejerean »

shaunxcode wrote: post #109

The real issue here that people don't seem to want to face is the WHY. Why do so many people want to check out of life completely by abusing medicine? If we don't address that nothing is going to stop the drug abuse let alone the relapse and overdose. I'm not talking about "more 12 step" here but more of a Frommian psychoanalytic approach. You are broken because society is broken. You have the ability to change yours…

I think quite a lot of people ended up addicted to opioids against their will, by starting with being over prescribed highly addictive pain medication which then ended up making them addicted to opioids, and then later on ended up trying to feed that habit from the streets once the easy access to pain meds dried up.

https://www.doj.nh.gov/news/2022/20220303-settlement-purdue-...

Personally I've been avoiding oxycontin like the plague for that reason. I had two surgeries where the doctors wanted to give me oxy to manage the pain afterwards and I refused to take them. It turned out in both cases the pain was manageable with less addictive options, so I'm not clear why they reached straight for prescribing opioids in the first place.

Re: Fentanyl vaccine tested in rats

#163

Post by newsclues »

fasthands9 wrote: post #112
shaunxcode wrote: post #109

The real issue here that people don't seem to want to face is the WHY. Why do so many people want to check out of life completely by abusing medicine? If we don't address that nothing is going to stop the drug abuse let alone the relapse and overdose. I'm not talking about "more 12 step" here but more of a Frommian psychoanalytic approach. You are broken because society is broken. You have the ability to change yours…

I guess I'm a bit torn on this. Even if we had an extremely fair and equitable society with growth I imagine there'd still be plenty of people who feel rejected or lonesome at times. Or just like the feeling that these drugs give them above normal drugs. I drink alcohol a couple times a week and do edibles once a month. I'm sure some would argue I'm not fulfilled but I think the easier explanation is that a lot of ti…

That sounds like a healthy amount of drugs. For people with self control like that, I think it would be healthy to trip once or twice a year and use stimulants (cocaine) for a party once a year.

A heroin vacation to an opium den on occasion sounds wonderful.

I certainly have used drugs socially (LSD in clubs or concerts can be fun), but also use them cannabis alone frequently.

Re: Fentanyl vaccine tested in rats

#165

Post by kstrauser »

LarryMullins wrote: post #154
kstrauser wrote: post #121

Earlier quoted context omitted.

If I fall off a ladder and break my leg, I want the good stuff. I’ve found old bottles of expired Vicodin and such around that I was prescribed but never finished. I have zero interest in recreationally using opiates. I also have zero interest in bravely tolerating agonizing pain if I don’t have to.

It's easy to say this when you already know that you, personally, can resist the temptation of abusing drugs like Vicodin. Personally, I refuse all pain killers except OTC and local anesthetics like novocaine. I rather risk biting through my tongue than getting addicted to that shit.

I get that, but that doesn't mean there's no room for powerful painkillers for the situations that call for them. If someone dying from cancer wants to be stoned out of their minds to avoid the pain, I'm all for letting them. You and I don't want that because our current circumstances don't call for it. Someday, they might. If that day comes, I wouldn't want to live in a world without access to strong analgesics.

Re: Fentanyl vaccine tested in rats

#166

Post by cantSpellSober »

Izkata wrote: post #146
cantSpellSober wrote: post #131

Earlier quoted context omitted.

No, I think it still meant something that reduces the spread infectious diseases. Like the COVID and Flu vaccines, the Polio vaccine does not provide 100% immunity to 100% of recipients. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974751/

> something that reduces the spread infectious diseases. Like the COVID That one doesn't do that though.

don't forget the microchips amirite?!

Re: Fentanyl vaccine tested in rats

#167

Post by buzzert »

t433 wrote: post #139
kstrauser wrote: post #118

Earlier quoted context omitted.

They’re adding Fentanyl to everything now. I have Burning Man-adjacent friends who take ecstasy once a year at festivals, and they’re terrified of getting a tainted dose. This affects many more people than just those addicted to opiates.

Legalize everything and produce it pharmaceutically, and this problems pretty much disappears.

A better way to frame the drug legalization issue is, "should pharmaceutical companies be allowed to profit from incredibly addictive drugs?"

Does that framing change your mind at all? Sure, small-time drug dealers are currently allowed to profit from it. Once they get big enough though, they're usually stopped by the DEA.

The idea of giving this enormous profit incentive to multi-million dollar corporations with huge advertising budgets is absolutely terrifying to me.

Re: Fentanyl vaccine tested in rats

#168

Post by cmyr »

SpeedilyDamage wrote: post #150
hasmolo wrote: post #145

Earlier quoted context omitted.

can you elaborate?

“ Illegal drugs increase crime, partly because some users turn to crime to pay for their habits and partly because some users are stimulated by certain drugs to act more violently. Legalization, however, will not affect addiction and its effects on the propensity to violence. Instead of legalizing drugs, better treatment, education, and research are needed to curb dependency on drugs and the adverse health and social…

'illegal drugs' is a pretty broad brush, and treating opiods and psychedelics equivalently is silly. Surely treatment, education and research would all be far easier alongside decriminalization?

Re: Fentanyl vaccine tested in rats

#169

Post by cwkoss »

wswope wrote: post #133
wdhilliard wrote: post #75

Does this prevent death or just the perceived effects of the drug? This could be very dangerous for users who relapse. There is a known pattern of users who get off opioids then relapse and die because their bodies can no longer tolerate the doses that they were used to taking before they quit. This could have a similar effect where users take the drug, don't feel it, and then increase their dose to lethal levels hop…

Can you elaborate on your point of confusion? The mechanism of action was explained in the article.

If the vaccine only suppresses opioid euphoria, users would continue dosing assuming they needed a higher dose to feel the effects leading to overdose and have possible respiratory failure.

Re: Fentanyl vaccine tested in rats

#170

Post by htag »

calibas wrote: post #53

Oh boy, the pharmaceutical companies can sell a new product to help solve the mess that one of their previous products created. An opioid that's more potent, more addictive, and more deadly than heroin should never have gone to market in the first place. It speaks of enormous corruption and a complete lack of ethics when regulators didn't see an issue with fentanyl and let it move forward. The "but people are in pain…

> It speaks of enormous corruption and a complete lack of ethics when regulators didn't see an issue with fentanyl and let it move forward.

Do you think there would be a meaningful difference in the volume of illicit fentanyl if it was never approved by the FDA?

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