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Endonuclease fingerprint indicates a synthetic origin of SARS-CoV-2?

biorxiv.org

161–170 of 250 posts

Re: Endonuclease fingerprint indicates a synthetic origin of SARS-CoV-2?

#161
post #66

I've seen several papers with the opposite conclusion. Why do we only see the lab leak hypothesis front paged on HN?

I have trouble understanding your point. Do you mean that HN front page should only show articles which are in line with the most common papers?

Re: Endonuclease fingerprint indicates a synthetic origin of SARS-CoV-2?

#163
post #43

I Honestly thought it was common belief that corona come from that lab in china. But now after reading this, I searched a bit and read up on it and I guess it is still a somewhat honest debate on the topic. Even if it was lab made, it would be sort of stupid to dig in to it, due to the political nature of the matter. What happened happened, most likely the release would have been accidental, so why play blame games.

If it was released from a lab, no matter whether or not it was accidental, Covid would be the mother of all torts. The entire planet can show harm and will be very interested in recovering their losses from the entity that mis-handled a lethal virus.

Yup, I think that's the real worry of CCP officials and other world leaders, that not only will China lose face, lose influence, but also the world will demand reperation. That might cause a collapse of the already unstable Chinese system with ripple effects all over the world.

Re: Endonuclease fingerprint indicates a synthetic origin of SARS-CoV-2?

#165
post #72
post #71

Earlier quoted context omitted.

A drug addict with a $14T GDP. With ~7M deaths and a ~$1-10M value of human life [1], that's $7-70T in losses in lives alone, before lost productivity and economic value. [1] https://en.wikipedia.org/wiki/Value_of_life#:~:text=In%20Wes... .

Only if liability transfers to the state. Even if state-owned, plenty of state-owned enterprises have limited liability.

Even if that state has nukes?

Re: Endonuclease fingerprint indicates a synthetic origin of SARS-CoV-2?

#166

Genuinely surprises me that there are people out there who think or have been persuaded the virus is of natural origin. The lab right next to the market was literally studying and experimenting with the exact same type of virus. How can a someone think that that's just a coincidence? Add that to the fact that the funding for that research lab was approved by the same guy who become the de facto thought leader on the…

Exactly this. I'm completely stunned how everybody seems to be ignoring the fact that the closest relatives of the Covid virus are in Yunnan, which is 1500 km away from Wuhan, or even further, in Laos. So a zoonotic origin of the outbreak which started in the Wuhan market would have involved animals transported to the market over 1500km or more. Doesn't anybody ask themselves, why Wuhan? Why was there no outbreak in any other city in China that was closer to Yunnan? Or even some in some market in Yunnan itself?

Re: Endonuclease fingerprint indicates a synthetic origin of SARS-CoV-2?

#167
post #134
post #110

Earlier quoted context omitted.

> It makes the pandemic deterministic (bad lab security means an outbreak) instead of stochastic "Bad lab security means an outbreak" is also stochastic though?

Not in the same way - it is admittedly still stochastic, but the product of conscious though, decisions, etc. that have very obvious bad actors and process improvements. So semi-deterministic might be a fairer way to put it. But at the very least, "Stochastic with a much, much smaller threat surface".

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Re: Endonuclease fingerprint indicates a synthetic origin of SARS-CoV-2?

#168

Genuinely surprises me that there are people out there who think or have been persuaded the virus is of natural origin. The lab right next to the market was literally studying and experimenting with the exact same type of virus. How can a someone think that that's just a coincidence? Add that to the fact that the funding for that research lab was approved by the same guy who become the de facto thought leader on the…

My Occam's razor says that every other virus has a natural origin, why wouldnt this one too? Maybe your razor needs sharpening?

You seem to think a natural origin virus can't be A) examined in a lab, and leaked; B) cultured in a lab, and leaked; C) tweaked in a lab, and leaked.

All three of these are possible. And all are compatible with your Occam's razor (and mine).

My bet is with option C.

Lab leak of a natural-origin, but tweaked, virus.

Yes, it can be both natural origin and tweaked. When you tweak something, you have to start with a something, and that something can have a natural origin.

The evidence against the lab leak appears cooked up based on data provided by interested authorities in China, and was assembled and presented by compromised people (people in the field with an active interest in protecting their own field) who actively promoted the false claim that they had no conflict of interest.

Re: Endonuclease fingerprint indicates a synthetic origin of SARS-CoV-2?

#169
post #100

Earlier quoted context omitted.

>Thirdly, this paper emphasizes the strong impact of the COVID pandemic and asserts that understanding the origins of the virus would necessarily aid in preventing future pandemics. This does not clearly follow. Especially if the virus had natural selection origins there is no clear and obvious way of systematically reducing risk. Simply living or traveling where host populations like bats live could be enough to gen…

> first purposeful extinction Smallpox? And extinction of Guinea worm is in process.

Fair point

Re: Endonuclease fingerprint indicates a synthetic origin of SARS-CoV-2?

#170

Genuinely surprises me that there are people out there who think or have been persuaded the virus is of natural origin. The lab right next to the market was literally studying and experimenting with the exact same type of virus. How can a someone think that that's just a coincidence? Add that to the fact that the funding for that research lab was approved by the same guy who become the de facto thought leader on the…

My Occam's razor says that every other virus has a natural origin, why wouldnt this one too? Maybe your razor needs sharpening?

What do you think "gain of function" research is even doing? Starting with natural origin viruses, and tweaking them.
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