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Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

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Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#161

Post by swayvil »

ciphol wrote: post #156
swayvil wrote: post #25

Could covid not actually be just a disease? Maybe it's a disease + chronic unhealth. Due to age, pollution, obesity, bad diet, sitting on yr butt too much and/or etc

Nearly all diseases are worse if you're in bad health to begin with. That doesn't make them "not just diseases".

Well if they have no symptoms then they aren't really diseases, right?

And there are a thousand species of varmint that inhabit our body without helping or hurting anyway.

So yes, massive unhealth can definitely spell the difference there.

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#162

Post by mlyle »

nradov wrote: post #60
SOLAR_FIELDS wrote: post #56

Earlier quoted context omitted.

One of my more bizarre long COVID symptoms was blood vessel leakage on my feet. One day a month or so after getting over COVID my feet started noticeably swelling. I was worried I had a clot in my leg so I went to the ER but sonogram came out fine. Turns out I had worn too-tight shoes the day before and the vessels in my feet had swelled/leaked. This was my same pair of shoes I had always worn at same tightness (they…

Why do you know it had to be COVID related? Many conditions can cause swollen feet.

It's reasonable to wonder if the illness you just recovered from is causing some ongoing symptoms, especially when many other people are experiencing ongoing morbidity from that illness.

In the end, when it comes to individual cases of anything (even conditions we have a very strong understanding of), all we can rely upon is guesswork. (e.g. even if we know A causes significantly increased rates of B in study populations based on RCT evidence, it still doesn't tell us for any given person with A & B that their A caused B).

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#163

Post by SketchySeaBeast »

swayvil wrote: post #161
ciphol wrote: post #156

Earlier quoted context omitted.

Nearly all diseases are worse if you're in bad health to begin with. That doesn't make them "not just diseases".

Well if they have no symptoms then they aren't really diseases, right? And there are a thousand species of varmint that inhabit our body without helping or hurting anyway. So yes, massive unhealth can definitely spell the difference there.

I'm not following. For some people a cold can have basically no symptoms and can even spread asymptomatically, and for most people it's just an irritation, but for the especially vulnerable it can kill. Would you argue that the common cold is also not a disease?

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#164

Post by _3u10 »

johncearls wrote: post #108
merpnderp wrote: post #64

Earlier quoted context omitted.

Placebo effect accounts for changes in their blood markers for micro clots? I'm a big believer in the power of the mind, but this seems a stretch.

It could also simply be time. To me this is obviously a small study that should be followed up (quickly) with a double blind, randomized trial. Until then, I'd be hesitant to put a bunch of ppl on anticoagulants.

My advice, don't prescribe people anticoagulants until you're satisfied it's safe for your patients.

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#165

Post by jonathan-adly »

favorited wrote: post #123
allturtles wrote: post #85

Earlier quoted context omitted.

To be clear in case it's not clear to others, the PPI is not the 'regime' that creates the risk of bleeding, it's the thing you take to provide some stomach protection against the damage/potential damage from the other drugs.

Right. PPIs are available without prescriptions in the US, and are considered very low risk medications.

Using PPIs for a short duration is safe, using PPIs chronically is not safe and the risks have to be weighted very carefully. It's by far the most intervened on medications by clinical pharmacists (usually discontinuing for inappropriate use)

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#166

Post by _3u10 »

iamthepieman wrote: post #76
merpnderp wrote: post #64

Earlier quoted context omitted.

Placebo effect accounts for changes in their blood markers for micro clots? I'm a big believer in the power of the mind, but this seems a stretch.

The point is that without a control group there's no way to know.

Even with a control group, there's no way to know.

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#167

Post by texasbigdata »

iamthepieman wrote: post #76
merpnderp wrote: post #64

Earlier quoted context omitted.

Placebo effect accounts for changes in their blood markers for micro clots? I'm a big believer in the power of the mind, but this seems a stretch.

The point is that without a control group there's no way to know.

I drove to Germany to see the machines. Spoke to the doc admistering it. It's a potentially painful almost full day procedure. We discussed the placebo thing. I'm not an expert on medical ethics but personally I would not want to be intubated (potentially wrong word) into that thing for hours and not get treatment.

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#168

Post by texasbigdata »

aarongray wrote: post #55
jokethrowaway wrote: post #37

Sounds exactly like chronic fatigue syndrome, I don't know why we keep calling it Long COVID while we have a name for it. https://www.nhs.uk/conditions/chronic-fatigue-syndrome-cfs/ > Suggested causes or triggers for ME/CFS include: > viral infections, such as glandular fever > bacterial infections, such as pneumonia > problems with the immune system > a hormone imbalance > your genes – ME/CFS seems to be more common…

Tell your friend to look into dysautonomia. There are some cutting edge treatments for chronic fatigue syndrome, they just haven't become mainstream knowledge yet. The two most effective approaches are using neuroplasticity exercises to retrain the limbic system (cheap, but time consuming - an hour a day for 6 months): https://ansrewire.com/ https://retrainingthebrain.com/ Or doing microcurrent neurofeedback (costs ~…

God bless you for this. Seriously.

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#169

Post by jonathan-adly »

I was rounding in the ICU when COVID hit, we knew this 2 weeks in - so not new information at all. All my patients got a higher dose of Lovenox (anticoagulant) as soon as they hit the unit.

The trick is balancing risk vs. benefits. Anticoagulants and antiplatelet will kill a 30 yo healthy person who slips on ice and hit his head. Your mild concussions are now massive brain bleeds.

Re: Antiplatelet and anticoagulant therapy resolves long covid in 24 patients

#170

Post by texasbigdata »

mikeyouse wrote: post #121
swader999 wrote: post #117

Earlier quoted context omitted.

What specifically in the linked protocol do you disagree with?

I don't need to do a line-by-line rebuttal of a Covid protocol my HVAC technician wrote -- though he likely did more to help the pandemic by changing out HEPA air filters than the Front Link covid quacks did with their awful advice and martyr complex. If someone is catastrophically and unapologetically wrong on problem 1a, you don't really need to pay attention to their solution to problem 1b.

Super not helpful. Also, some of your points could be debated (fluvoxamine recently, statins in trials, vitamin C, etc). But overall the tone makes it hard to have a civil discussion.
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