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Tinnitus Treatment from Neuromod

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Re: Tinnitus Treatment from Neuromod

#161
post #19

I've been following tinnitus research and the most promising treatment is FX-322 [1]. It's a drug that will treat hearing loss, but it could also help diminish tinnitus. It's currently in phase 2a [2] and results come out next year [3]. [1] https://hear2tell.com/2020/09/29/frequency-therapeutics-fx-3... [2] https://clinicaltrials.gov/ct2/show/NCT04120116 [3] https://www.hearinglosstreatmentreport.com/estimated-fx-322…

Thanks for the resources. I'm usually following https://www.tinnitustreatmentreport.com/ for all things tinnitus and that's where I saw the FX-322

Re: Tinnitus Treatment from Neuromod

#162
post #138

Earlier quoted context omitted.

can you link the videos that worked for you?

Might be the bob and brad physio videos. Not op, but was looking at this recently and they have some of the most prominent ones.

Yea those are really good ones.

For most topics I recommend dr Jo as a starting point Bob and Brad if they want to step up the game.

Re: Tinnitus Treatment from Neuromod

#163

Earlier quoted context omitted.

Drops seem safer to me. I've had good success with Debrox, but there are a variety of brands. https://www.debrox.com/products/debrox-earwax-removal-kit

The drops have not been shown to be any more effective than plain water. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD... I dislike flushing my ear with a syringe or squeeze bulb as it is uncomfortably loud and it seems possible to damage the eardrum with overpressure. It is also difficult to tell if it is working or how long you should continue doing it to ensure a clean ear, especially if the ear is…

I'd not seen that Cochrane study, that's interesting, thanks for sharing.

Sticking something pointy in your ear seems to carry its own risks. How do you ensure you don't puncture your eardrum?

Re: Tinnitus Treatment from Neuromod

#164
post #85

I've often wondered why sometimes it's worse than others. It's always there. I always hear the ringing, but most times I can ignore it, but there are other times it just seems so much louder. I would like to know what all those triggers are so I can try to avoid them. Some are obvious - real loud noises, heavy exercise, etc, but others not so much.

I've been dealing with it for nearly 20 years now. I'm apparently fairly adept at putting it to the background these days, because I mostly don't notice it except for when it's particularly quiet, or something specifically triggers my awareness of it. Certain sounds in certain frequency ranges trigger it off too. My youngest kid had a playful shriek thing she did that would palpably hurt me and cause it to kick off.…

It's the same for me too, but stress triggers mine as well or at least doesn't let me ignore it. I'm considering flying to Ireland to try this as soon as we're allowed. I'd be on a flight right now if I could. I just want to experience silence again, at least for an hour or two.

Re: Tinnitus Treatment from Neuromod

#165

Earlier quoted context omitted.

Are you using cotton swaps in your ears? What might be happening is that you shove wax in, clogging your ears and giving you tinnitus. That used to happen to me - the ear wax wasn't the problem, trying to clean it was.

To clean your ears yourself you need something like this: https://www.japantrendshop.com/coden-ear-scope-13000-standar... I thought it was ridiculous when I first saw it but I took a chance on it and it is actually a great product. You can clearly see everything and clean without damaging your ear. If you've ever had to go to the doctor to clear a blocked ear, you need one of these. With occasional use (~once/month)…

Its absolutely ridiculous and stupid to spend that much money.

You can get a spray bottle with a special tip from amazon and the whole kit is about $20 and will do just as good of a job and clean your ear perfectly. I have one of the amazon cleaning kits and its great. Doctor told me to get it when my hearing was muffled in one ear

Re: Tinnitus Treatment from Neuromod

#166
post #115

I’m a neuroscientist and just read their “phase 2b protocol” paper. As far as I can tell, there are no actual control groups. Registering a trial with clinicaltrials.gov is a nice step, but they don’t compare at all to patient improvements in people that don’t receive treatment let alone a sham. Thus, the study does not appear designed to prove efficacy even though they will surely claim it.

Bingo.

Re: Tinnitus Treatment from Neuromod

#167
post #19

I've been following tinnitus research and the most promising treatment is FX-322 [1]. It's a drug that will treat hearing loss, but it could also help diminish tinnitus. It's currently in phase 2a [2] and results come out next year [3]. [1] https://hear2tell.com/2020/09/29/frequency-therapeutics-fx-3... [2] https://clinicaltrials.gov/ct2/show/NCT04120116 [3] https://www.hearinglosstreatmentreport.com/estimated-fx-322…

Thanks for the resources. I'm usually following https://www.tinnitustreatmentreport.com/ for all things tinnitus and that's where I saw the FX-322

Tinnitus Treatment Report creator here. Glad you find the site useful and thank you for sharing the link. Appreciated.

Re: Tinnitus Treatment from Neuromod

#168
post #19

I've been following tinnitus research and the most promising treatment is FX-322 [1]. It's a drug that will treat hearing loss, but it could also help diminish tinnitus. It's currently in phase 2a [2] and results come out next year [3]. [1] https://hear2tell.com/2020/09/29/frequency-therapeutics-fx-3... [2] https://clinicaltrials.gov/ct2/show/NCT04120116 [3] https://www.hearinglosstreatmentreport.com/estimated-fx-322…

Hearing Loss Treatment Report creator here. Thank you for referencing the site, I appreciate it.

Re: Tinnitus Treatment from Neuromod

#169

Earlier quoted context omitted.

The drops have not been shown to be any more effective than plain water. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD... I dislike flushing my ear with a syringe or squeeze bulb as it is uncomfortably loud and it seems possible to damage the eardrum with overpressure. It is also difficult to tell if it is working or how long you should continue doing it to ensure a clean ear, especially if the ear is…

I'd not seen that Cochrane study, that's interesting, thanks for sharing. Sticking something pointy in your ear seems to carry its own risks. How do you ensure you don't puncture your eardrum?

Same way you don't cut yourself when using a knife, by watching and being careful. The endoscope makes it possible to see.

Re: Tinnitus Treatment from Neuromod

#170

Earlier quoted context omitted.

I find Amazon reviews fairly useless these days. Most good ratings are just because of fake or paid reviewers or other scams like switching the product while keeping the reviews, combining two products in one listing, and probably others I don't know about. Amazon seems powerless to fix it, or maybe they just don't think they need to care. I haven't tried any of the phone based endoscopes but I expect the latency and…

How would a camera to smartphone connector add appreciable latency?

I don't know, but I am constantly amazed at the ingenuity of the people who manage to add latency to pretty much all modern hardware and software.
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