This article provides no meaningful references (but some useless ones). This is a really interesting question, but essentially left unaddressed.
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Medications that change who we are
161–170 of 289 posts
Re: Medications that change who we are
#162Let's also consider the other direction -- how fresh vegetables and fruit, plus whole grains, beans, nuts, seeds, and herbs improve mood, behavior, resilience. Throw in some vigorous exercise, and for most people, drugs can't do better, without the drugs' side effects and cost. For many people, switching from a standard American diet to largely those ingredients would register as changing who they are. I just finishe…
Let's also consider the other direction -- how fresh vegetables and fruit, plus whole grains, beans, nuts, seeds, and herbs improve mood, behavior, resilience. Throw in some vigorous exercise, and for most people, drugs can't do better, without the drugs' side effects and cost. If you look at health outcomes, this is sort of obviously not true. I don't mean the health benefits of the things you mention, I mean the "f…
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Re: Medications that change who we are
#163Let's also consider the other direction -- how fresh vegetables and fruit, plus whole grains, beans, nuts, seeds, and herbs improve mood, behavior, resilience. Throw in some vigorous exercise, and for most people, drugs can't do better, without the drugs' side effects and cost. For many people, switching from a standard American diet to largely those ingredients would register as changing who they are. I just finishe…
Let's also consider the other direction -- how fresh vegetables and fruit, plus whole grains, beans, nuts, seeds, and herbs improve mood, behavior, resilience. Throw in some vigorous exercise, and for most people, drugs can't do better, without the drugs' side effects and cost. If you look at health outcomes, this is sort of obviously not true. I don't mean the health benefits of the things you mention, I mean the "f…
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Re: Medications that change who we are
#164Let's also consider the other direction -- how fresh vegetables and fruit, plus whole grains, beans, nuts, seeds, and herbs improve mood, behavior, resilience. Throw in some vigorous exercise, and for most people, drugs can't do better, without the drugs' side effects and cost. For many people, switching from a standard American diet to largely those ingredients would register as changing who they are. I just finishe…
Let's also consider the other direction -- how fresh vegetables and fruit, plus whole grains, beans, nuts, seeds, and herbs improve mood, behavior, resilience. Throw in some vigorous exercise, and for most people, drugs can't do better, without the drugs' side effects and cost. If you look at health outcomes, this is sort of obviously not true. I don't mean the health benefits of the things you mention, I mean the "f…
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Re: Medications that change who we are
#165Let's also consider the other direction -- how fresh vegetables and fruit, plus whole grains, beans, nuts, seeds, and herbs improve mood, behavior, resilience. Throw in some vigorous exercise, and for most people, drugs can't do better, without the drugs' side effects and cost. For many people, switching from a standard American diet to largely those ingredients would register as changing who they are. I just finishe…
Let's also consider the other direction -- how fresh vegetables and fruit, plus whole grains, beans, nuts, seeds, and herbs improve mood, behavior, resilience. Throw in some vigorous exercise, and for most people, drugs can't do better, without the drugs' side effects and cost. If you look at health outcomes, this is sort of obviously not true. I don't mean the health benefits of the things you mention, I mean the "f…
Are you really trying to say that promoting a nutritious diet supported by physical activity doesn't work for "most people"? You call that engaged advocacy?
What he claimed is true and backed by multiple studies. Doing a healthy dose of physical activity with a healthy diet can only be beneficial, no downside whatsoever. It's quite underrated I guess. Too many humans wish for a magic pill, they delude themselves into thinking that it must be better than healthy living habits, since it's more modern. People are looking for the lazy fix.
Re: Medications that change who we are
#166I take gabapentin for a spinal issue (nerve damage in my spine) and it has a drastic and noticeable effect, I'm naturally quiet and introverted but when I take the higher prescribed dose that changes radically, I become outgoing and talkative, I have more confidence and I seem to be more creative (though that could just be the reduction in pain). It definitely alters my mood and I can feel it happen.
That's essentially what MDMA does too.
It is quite different than MDMA in practice though I think and even despite its name it does not bind to GABA I would still more liken it to the positive/social feelings of alcohol than mdma (don't mix alcohol and gabapentin though, it can be dangerous).
Re: Medications that change who we are
#167Let's also consider the other direction -- how fresh vegetables and fruit, plus whole grains, beans, nuts, seeds, and herbs improve mood, behavior, resilience. Throw in some vigorous exercise, and for most people, drugs can't do better, without the drugs' side effects and cost. For many people, switching from a standard American diet to largely those ingredients would register as changing who they are. I just finishe…
Let's also consider the other direction -- how fresh vegetables and fruit, plus whole grains, beans, nuts, seeds, and herbs improve mood, behavior, resilience. Throw in some vigorous exercise, and for most people, drugs can't do better, without the drugs' side effects and cost. If you look at health outcomes, this is sort of obviously not true. I don't mean the health benefits of the things you mention, I mean the "f…
> this is sort of obviously not true... I mean the "for most people" part.
> I think it probably isn't good advocacy
That's pretty strong, can you at least explain why you think that?
Re: Medications that change who we are
#168Let's also consider the other direction -- how fresh vegetables and fruit, plus whole grains, beans, nuts, seeds, and herbs improve mood, behavior, resilience. Throw in some vigorous exercise, and for most people, drugs can't do better, without the drugs' side effects and cost. For many people, switching from a standard American diet to largely those ingredients would register as changing who they are. I just finishe…
This sounds more like diet marketing. People have such varying success with different diets that one set of foods simply cannot fit all. Exercise is a different story. The most likely to bring about the improvements you describe.
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Re: Medications that change who we are
#169Let's also consider the other direction -- how fresh vegetables and fruit, plus whole grains, beans, nuts, seeds, and herbs improve mood, behavior, resilience. Throw in some vigorous exercise, and for most people, drugs can't do better, without the drugs' side effects and cost. For many people, switching from a standard American diet to largely those ingredients would register as changing who they are. I just finishe…
This sounds more like diet marketing. People have such varying success with different diets that one set of foods simply cannot fit all. Exercise is a different story. The most likely to bring about the improvements you describe.
It's hard to believe you made such a comment without including more doubts in your claim. I will leave one link, I hope it changes your mind and people mind if they agree with your comment. But there's more science supporting that a good nutrition help the brain: https://www.health.harvard.edu/blog/nutritional-psychiatry-y...
Re: Medications that change who we are
#170This article provides no meaningful references (but some useless ones). This is a really interesting question, but essentially left unaddressed.
You're a cardiology fellow, so you're likely much better versed in this than me, but take a look at the paper cited here:
Sure looks like they were doing multiple comparisons until they found a happenstance significant subgroup. : |
"Several studies have supported a potential link between irritability and statins, including a randomised controlled trial – the gold-standard of scientific research – that Golomb led, involving more than 1,000 people. It found that the drug increased aggression in post-menopausal women though, oddly, not in men."
https://journals.plos.org/plosone/article?id=10.1371/journal...
They adjusted for multiple comparisons, and after that even the post menopausal group wasn't significant. The bit about how that doesn't matter because testosterone mechanisms and independent chance seems very hand-wavey to me.
(Moved my broader comment on this from a reply here to it's own reply to the thread.)